Results 121 to 130 of about 346,512 (160)

Expression of insulin‐like growth factor 1 in sarcomas

Histopathology, 1990
The expression of insulin‐like growth factor‐1 (IGF‐1) was studied in normal tissues, in eight benign lesions and in 50 sarcomas. In palmar fibromatosis the spindle cells in cell‐dense areas exhibited a strong immunoreactivity. IGF‐1 was variably found in leiomyosarcomas (7/8), malignant schwannomas (7/9), synovial sarcomas (2/3), liposarcomas (3/6 ...
P J, Roholl, A, Skottner, I, Prinsen, C J, Lips, W, Den Otter, J A, Van Unnik   +5 more
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Elevated insulin‐like growth factor‐1 in Cushing’s disease [PDF]

Clinical Endocrinology, 2019
SummaryObjectiveTo determine if patients with untreated Cushing's disease have higher serum insulin‐like growth factor‐1 (IGF‐1) compared to matched controls, and if IGF‐1 decreases following remission of Cushing's disease.DesignRetrospective case‐control study matching Cushing's disease cases to control patients for adenoma size, age, sex, diabetic ...
Katherine English, Viral Chikani, Goce Dimeski, Warrick J. Inder   +3 more
openaire   +4 more sources

Insulin-Like Growth Factor 1 in the Cardiovascular System

2018
Non-communicable diseases, such as cardiovascular diseases, are the leading cause of mortality worldwide. For this reason, a tremendous effort is being made worldwide to effectively circumvent these afflictions, where insulin-like growth factor 1 (IGF1) is being proposed both as a marker and as a central cornerstone in these diseases, making it an ...
Gabriel A, Aguirre, José Luis, González-Guerra, Luis, Espinosa, Inma, Castilla-Cortazar   +3 more
openaire   +2 more sources

Expression of insulin-like growth factor-1 and insulin-like growth factor-1 receptors in EL4 lymphoma cells overexpressing growth hormone

Cellular Immunology, 2005
Almost all of the previous studies with growth hormone (GH) have been done with exogenously supplied GH and, therefore, involve actions of the hormone through its receptor. However, the actions of endogenous or lymphocyte GH are still unclear. In a previous study, we showed that overexpression of GH (GHo) in a lymphoid cell line resulted in protection ...
Douglas A, Weigent, Robyn E, Arnold
openaire   +2 more sources

Insulin-Like Growth Factor 1 Expression in Thyroid Tumors

Applied Immunohistochemistry & Molecular Morphology, 2000
Insulin-like growth factor 1 (IGF-1) likely is involved in thyrocyte proliferation via autocrine mechanisms, but limited data are available on its in vivo expression in thyroid neoplasms. This prompted us to explore IGF-1 expression at the protein and mRNA levels and IGF-1 receptor (IGF-1rec) immunoreactivity in normal and neoplastic thyroids (50 ...
Maiorano E, Ciampolillo A, Viale G, Maisonneuve P, Ambrosi A, Triggiani V, Marra E, Perlino E   +7 more
openaire   +4 more sources

The role of insulin-like growth factor-1 in lactation

Gene
Generally, Insulin-like growth factor 1 (IGF-1) is believed to regulate lactation activity by promoting cell proliferation and differentiation. With the advancement of research, IGF-1 has been discovered to play an important role in different stages of lactation.
Shuo, Zheng, Xi, Chen, JiaY, Fang, Yi, Li, XingY, Xiao, XunM, Zhang, LiB, Zhang, YunY, Cheng, LinL, Hao   +8 more
openaire   +2 more sources

Insulin-like growth factor-1 and insulin-like growth factor-binding protein-3 in women with premenstrual syndrome

Fertility and Sterility, 1998
To determine whether women with premenstrual syndrome (PMS) have aberrations of the GH axis as has been demonstrated in individuals with depression.Prospective trial.Department of Obstetrics and Gynecology, University of California, Los Angeles.After prospective screening, 32 healthy women with PMS and 32 asymptomatic controls completed the study ...
A J, Rapkin, M, Cedars, M, Morgan, L, Goldman   +3 more
openaire   +2 more sources

Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3

Journal of the American Academy of Dermatology, 2000
A recent report suggested that men with vertex balding have higher levels of plasma insulin-like growth factor 1 (IGF-1). The association of its major carrier protein, insulin-like growth factor binding protein 3 (IGFBP-3), with male pattern hair loss has not been examined.We evaluated the relations of plasma concentrations of IGF-1 and IGFBP-3 with ...
E A, Platz, M N, Pollak, W C, Willett, E, Giovannucci   +3 more
openaire   +2 more sources

The role of insulin - like growth factor - 1 on steatohepatitis.

Acta gastro-enterologica Belgica, 2017
Recent studies have revealed that growth hormone and STAT5 were related to hepatosteatosis in mice. Loss of signal transducer and activator of transcription factor-5 leads to hepatosteatosis and impaired liver regeneration. We aimed to investigate the role of IGF-1 in steatosis with normal (SNLFT) and disturbed liver function tests (SDLFT) in humans.We
Ata, Naim, Karadag, Ibrahim, Beyan, Esin, Ertugrul, Derun Taner, Unsal, OKTAY, Bulur, Oktay, Dal, Kursat, Yeniova, Abdullah Ozgur, Baser, Salih, Karakaya, Serdar, Dagdeviren, Murat   +10 more
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Insulin‐Like Growth Factor‐1

Journal of the American Geriatrics Society, 2004
Colbert, L. H., Rosen, C., Goodpaster, B. H., Newman, A. B., Kritchevsky, S. B., Satterfield, S., Kanaya, A. M., Taaffe, D. R., Harris, T. B.   +8 more
openaire   +5 more sources