Results 111 to 120 of about 113,369,369 (332)

Dysregulated Cholesterol Metabolism, Chronic Inflammation, and Disability in Severe Progressive Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Dysregulated lipid metabolism, which can affect remyelination and neural repair, has not been extensively investigated in progressive multiple sclerosis (PMS). The goal was to examine whether dysregulated cholesterol metabolism was associated with disability in PMS. Methods The study sample comprised 53 Severe PMS patients (Expanded
Taylor R. Wicks, Mujeeb Shittu, Anna Wolska, Diala Ghazal, Bianca Weinstock‐Guttman, Alexander Burnham, Alan T. Remaley, Robert Zivadinov, Murali Ramanathan   +8 more
wiley   +1 more source

Expression of insulin-like growth factor family genes in clear cell renal cell carcinoma

, 2016
Aim of the study : Despite significant progress in the pathology of clear cell renal cell carcinoma (ccRCC), diagnostic and predictive factors of major importance have not been discovered. Some hopes are associated with insulin-like growth factors.
Urszula Mazurek, Ryszard Braczkowski, Michał Białożyt, Marta Plato, Bogumiła Braczkowska   +4 more
core   +1 more source

IGF2BP1 (insulin-like growth factor 2 mRNA binding protein 1) [PDF]

, 2011
Review on IGF2BP1 (insulin-like growth factor 2 mRNA binding protein 1), with data on DNA, on the protein encoded, and where the gene is ...
Ioannidis, P, Trangas, T
core   +1 more source

The impact of exercise on growth factors in postmenopausal women: a systematic review and meta-analysis

BMC Women's Health
Background Aging results in many changes in health status, body composition, muscle strength, and, ultimately, functional capacity. These changes coincide with significant alterations in the endocrine system, such as insulin-like growth factor-1 (IGF-1 ...
Yasaman Nasir, Mohammad Reza Hoseinipouya, Hesam Eshaghi, Mohammad Hossein Rahimi   +3 more
doaj   +1 more source

Patients improve, patterns persist: longitudinal stability of RA joint involvement patterns

Arthritis Care &Research, Accepted Article.
Objective Rheumatoid arthritis is a heterogeneous disease. Data‐driven approaches, from synovial histology to joint involvement patterns (JIPs), have sought to define clinically meaningful subgroups. Whether these subgroups represent stable phenotypes or transient disease states remains unclear.
Tjardo Maarseveen, Yasuo Nagafuchi, Kristina Lend, Seyam Alemyar, Herman Kasper Glas, Gerdur Gröndal, Bjorn Gudbjornsson, Espen A. Haavardsholm, Kim Hørslev Petersen, Jon Lampa, Merete Lund Hetland, Dan Nordström, Mike Nurmohamed, Mikkel Østergaard, Anna Rudin, Marte Schrumpf Heiberg, Tuulikki Sokka‐Isler, Till Uhlig, Josien Veris‐van Dieren, Ronald van Vollenhoven, Tom Huizinga, Marcel JT Reinders, Sytske Anne Bergstra, Erik van den Akker, Rachel Knevel   +24 more
wiley   +1 more source

Causal associations between the insulin-like growth factor family and sarcopenia: a bidirectional Mendelian randomization study

Frontiers in Endocrinology
ObjectiveInsulin-like growth factor (IGF) is closely associated with sarcopenia, yet the causal relationship of this association remains unclear.
Jili Liu, Meng Chen, Xin Xia, Zhaolin Wang, Yanqin Wang, Ling Xi   +5 more
doaj   +1 more source

2D Skeletal Muscle Thin Film Actuators Enhance Efficiency of Biohybrid Robots

Advanced Functional Materials, EarlyView.
2D skeletal muscle thin film actuators generate millinewton‐scale forces and millimeter‐scale strokes while remaining functional for over 30 days. Their force density is 20‐fold higher than 3D skeletal muscle actuators, enabling multi‐fin robots with tunable speed and multidirectional steering.
Maheera Bawa, Arielle Berman, Laura Schwendeman, Ferdows Afghah, Seanbiron Johnson, Ritu Raman   +5 more
wiley   +1 more source

Evaluating Serum Insulin-Like Growth Factor 1 and Insulin-Like Growth Factor Binding Protein 3 as Markers in Prostate Cancer Diagnosis

The International Journal of Biological Markers, 2016
Background Prostate-specific antigen (PSA) lacks specificity and sensitivity in discriminating prostate cancer (PCa) from benign prostatic hyperplasia (BPH) when the total PSA (tPSA) level is between 4 and 10 ng/mL.
Giulia Rainato, Aline S.C. Fabricio, Matelda Zancan, Lucia Peloso, Ruggero Dittadi, Mario Barichello, Andrea Fandella, Vincenzo Scattoni, Massimo Gion   +8 more
doaj   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

Advanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez, Ruth Tarpey, Benjamin Brennan, Bryan D. Boyle, Amir M. Alsharabasy, Abhik Mallick, Gabriella Bellavia, Abhay Pandit, Garry P. Duffy, Ruth E. Levey   +9 more
wiley   +1 more source

Astrocytic Insulin-Like Growth Factor-1 Protects Neurons Against Excitotoxicity

Frontiers in Cellular Neuroscience, 2019
BackgroundExogenous insulin like growth factor-1 (IGF-1) is known to be neuroprotective in animal models with brain insults, while it can also cause hyperexcitability in rodents.
Wei Chen, Bin He, Wusong Tong, Jinsong Zeng, Ping Zheng   +4 more
doaj   +1 more source