Results 251 to 260 of about 39,607,185 (297)

Growth Hormone and Insulin-Like Growth Factor-1

2016
Human growth hormone (GH) was first isolated from the human pituitary gland in 1945 and found to promote the growth of children with hypopituitarism. Since the formation of the World Anti-Doping Association, human GH has appeared on the list of forbidden substances.
Nicholls, A.R., Holt, Richard
openaire   +3 more sources

Insulin-like growth factor-1 and insulin-like growth factor binding protein-1 in early human pregnancy

Early Human Development, 1992
Insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-1 (IGFBP-1) were measured in amniotic fluid, extraembryonic coelomic fluid and maternal serum from 23 women with apparently normal first trimester pregnancies prior to termination. The levels of IGF-1 and IGFBP-1 were significantly higher in coelomic fluid than amniotic
N C, Wathen   +4 more
openaire   +2 more sources

Abundance of insulin-like growth factors 1 and 2, and type 1 insulin-like growth factor receptor in placentas of dogs

Animal Reproduction Science, 2020
Insulin-like growth factors (IGFs) are among the primary compounds regulating placental development. In bitches, relative abundance of IGF1, IGF2 and IGFR1 mRNA transcripts have been studied in the pre-implantation uterus and early endotheliochorial placentas.
Hernández, Rocío   +5 more
openaire   +3 more sources

Elevated insulin‐like growth factor‐1 in Cushing’s disease [PDF]

open access: possibleClinical Endocrinology, 2019
SummaryObjectiveTo determine if patients with untreated Cushing's disease have higher serum insulin‐like growth factor‐1 (IGF‐1) compared to matched controls, and if IGF‐1 decreases following remission of Cushing's disease.DesignRetrospective case‐control study matching Cushing's disease cases to control patients for adenoma size, age, sex, diabetic ...
Katherine English   +3 more
openaire   +4 more sources

Signaling by insulin-like growth factor 1 in brain

European Journal of Pharmacology, 2004
The homologous insulin and insulin-like growth factor (IGF) receptors are both expressed in the brain, in overlapping but distinct neuroanatomical patterns. In contrast to insulin, IGF1 is also highly expressed within the brain and is essential for normal brain development.
Carolyn A, Bondy, Clara M, Cheng
openaire   +2 more sources

Expression of insulin‐like growth factor 1 in sarcomas

Histopathology, 1990
The expression of insulin‐like growth factor‐1 (IGF‐1) was studied in normal tissues, in eight benign lesions and in 50 sarcomas. In palmar fibromatosis the spindle cells in cell‐dense areas exhibited a strong immunoreactivity. IGF‐1 was variably found in leiomyosarcomas (7/8), malignant schwannomas (7/9), synovial sarcomas (2/3), liposarcomas (3/6 ...
P J, Roholl   +5 more
openaire   +2 more sources

The role of insulin-like growth factor-1 in lactation

Gene
Generally, Insulin-like growth factor 1 (IGF-1) is believed to regulate lactation activity by promoting cell proliferation and differentiation. With the advancement of research, IGF-1 has been discovered to play an important role in different stages of lactation.
Shuo, Zheng   +8 more
openaire   +2 more sources

Expression of insulin-like growth factor-1 and insulin-like growth factor-1 receptors in EL4 lymphoma cells overexpressing growth hormone

Cellular Immunology, 2005
Almost all of the previous studies with growth hormone (GH) have been done with exogenously supplied GH and, therefore, involve actions of the hormone through its receptor. However, the actions of endogenous or lymphocyte GH are still unclear. In a previous study, we showed that overexpression of GH (GHo) in a lymphoid cell line resulted in protection ...
Douglas A, Weigent, Robyn E, Arnold
openaire   +2 more sources

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