Results 11 to 20 of about 416,432 (306)

Transferrin binds insulin‐like growth factors and affects binding properties of insulin‐like growth factor binding protein‐3 [PDF]

FEBS Letters, 2001
In the circulation, most of the insulin‐like growth factors (IGFs) are bound to a ternary 150 kDa complex with IGF‐binding protein (IGFBP)‐3 and the acid labile subunit. In the current study, we identify transferrin (Tf) by mass spectrometry, and immunoprecipitation as a component of a major IGF‐binding fraction separated from human plasma.
Storch, S., Kubler, B., Honing, S., Ackmann, M., Zapf, J., Blum, W., Braulke, Thomas   +6 more
openaire   +3 more sources

Cardiovascular disease risk markers in children under 10 years of age and their relationship with serum concentrations of IGF-1, IGFBP-1, IGFBP-2 and IGFBP-3

Revista de la Facultad de Medicina, 2020
Introduction: Any type of nutritional imbalance experienced during childhood will affect the health of an individual, both in their childhood and their adulthood.
Sorany Vera, Tatiana Figueroa, Luz Helena Aranzalez, Ismena Mockus   +3 more
doaj   +1 more source

Insulin-like growth factor binding protein 5: Diverse roles in cancer

Frontiers in Oncology, 2022
Insulin-like growth factor binding proteins (IGFBPs) and the associated signaling components in the insulin-like growth factor (IGF) pathway regulate cell differentiation, proliferation, apoptosis, and adhesion.
Jennifer A. Waters, Ixchel Urbano, Mikella Robinson, Carrie D. House, Carrie D. House   +4 more
doaj   +1 more source

Insulin-like growth factor binding protein-5 modulates muscle differentiation through an insulin-like growth factor-dependent mechanism. [PDF]

, 1996
The insulin-like growth factor binding proteins (IGFBPs) are a family of six secreted proteins which bind to and modulate the actions of insulin-like growth factors-I and -II (IGF-I and -II).
James, PL, Rotwein, P, Stewart, CE
core   +2 more sources

Kinetics of urinary cell cycle arrest markers for acute kidney injury following exposure to potential renal insults [PDF]

, 2018
Objectives: Urinary tissue inhibitor of metalloproteinase-2 and insulin-like growth factor binding protein 7 predict the development of acute kidney injury following renal insults of varied aetiology.
Aliaga, Bellomo, Bihorac, Bonventre, Charlton, Emlet, Goldstein, Gunnerson, Honore, Hoste, Hoste, Jia, Joannidis, Kane-Gill, Kashani, Kaufman, Kerr, Lewington, McDonald, Meersch, Mehta, Mehta, Murrary, Peng, Perazella, Uchino, Waring, Wu   +27 more
core   +1 more source

Insulin Like Growth Factor Binding Protein 7 as a Novel Diagnostic Marker in Sera of Iraqi Patients with Acromegaly

مجلة بغداد للعلوم, 2023
The purpose of this study was to measure serum levels of insulin-like growth factor-binding protein (IGFBP7), Insulin-like Growth Factor 1 (IGF-1), Growth Hormone (GH), Interleukin 6 (IL-6) and insulin in acromegaly patients and healthy controls.
Layla Othman Farhan, Baydaa Ahmed Abed, Kashtl Ghasaq J., Isam Noori Salman   +3 more
doaj   +1 more source

Estradiol, Progesterone, and Transforming Growth Factor α Regulate Insulin-Like Growth Factor Binding Protein-3 (IGFBP3) Expression in Mouse Endometrial Cells [PDF]

, 2009
Insulin-like growth factor 1 (IGF1) Is Involved in the proliferation of mouse and rat endometrial cells in a paracrine or autocrine manner. Insulin-like growth factor binding protein-3 (IGFBP3) modulates actions of IGFs directly or indirectly.
Hembree JR, Huynh H, Munetoshi Kanayama, Ohtsuki T, Ohtsuki T, Pierro E, Sakae Takeuchi, Shiraga M, Sumio Takahashi, Takaoka M, Tetsuya Maekawa   +10 more
core   +1 more source

Gene expression patterns of insulin-like growth factor 1, insulin-like growth factor 2 and insulin-like growth factor binding protein 3 in human placenta from pregnancies with intrauterine growth restriction [PDF]

, 2011
Introduction: In this study, we compared insulin-like growth factor (IGF)-gene expression patterns and characteristics of glucose and insulin metabolism in human placenta from pregnancies with or without intrauterine growth restriction (IUGR).
Börzsönyi, Balázs, Csanád, Mónika, Demendi, Csaba, Joó József, Gábor, Nagy, Zsolt, Pajor, Attila, Rigó, János, Tóth, Katalin   +7 more
core   +2 more sources

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits [PDF]

, 2016
The growth hormone/insulin-like growth factor (IGF) axis can be manipulated in animal models to promote longevity, and IGF-related proteins including IGF-I and IGF-binding protein-3 (IGFBP-3) have also been implicated in risk of human diseases including ...
Aschard, H. (Hugues), Bandinelli, S. (Stefania), Beekman, M. (Marian), Berndt, S.I. (Sonja), Bidlingmaier, M. (Martin), Broer, L. (Linda), Cappola, A.R. (Anne), Ceda, G.P. (Gian Paolo), Chanock, S.J. (Stephen), Chen, M.-H. (Ming-Huei), Chen, T.C. (Tai C.), Chen, Y.D. (Y.), Chung, J. (Jonathan), Del Greco Miglianico, F. (Fabiola), Duijn, C.M. (Cornelia) van, Eriksson, J. (Joel), Ferrucci, L. (Luigi), Friedrich, N. (Nele), Gnewuch, C. (Carsten), Goodarzi, M. (Mark), Grarup, N. (Niels), Guo, T. (Tingwei), Hammer, E. (Elke), Hayes, R.B. (Richard), Heemst, D. (Diana) van, Hicks, A.A. (Andrew), Hofman, A. (Albert), Houwing-Duistermaat, J.J. (Jeanine), Hu, F. (Frank), Hunter, D. (David), Husemoen, L.L.N. (Lise Lotte), Isaacs, A.J. (Aaron), Jacobs, K.B. (Kevin), Janssen, J.A.M.J.L. (Joop), Jansson, J.-O. (John-Olov), Jehmlich, N. (Nico), Johnson, S. (Simon), Juul, A. (Anders), Kaplan, R.C. (Robert), Karlsson, M. (Magnus), Kilpeläinen, T.O. (Tuomas), Kovacs, P. (Peter), Kraft, P. (Peter), Li, C. (Chao), Linneberg, A. (Allan), Liu, Y. (YongMei), Loos, R.J.F. (Ruth), Lorentzon, M. (Mattias), Lu, Y. (Yingchang), Maggio, M. (Marcello), Meigs, J.B. (James), Mellström, D. (Dan), Mägi, R. (Reedik), Nauck, M. (Matthias), Nethander, M. (Maria), Newman, A.B. (Anne B.), Ohlsson, C. (Claes), Pollak, M.N. (Michael), Pramstaller, P.P. (Peter Paul), Prokopenko, I. (Inga), Psaty, B.M. (Bruce), Qi, Q., Reincke, M. (Martin), Rimm, E.B. (Eric B.), Rotter, J.I. (Jerome I.), Saint Pierre, A. (Aude), Schurmann, C. (Claudia), Seshadri, S. (Sudha), Sjögren, K. (Klara), Slagboom, P.E. (Eline), Strickler, H.D. (Howard D.), Stumvoll, M. (Michael), Suh, Y. (Yousin), Sun, Q. (Qi), Svensson, J. (Johan), Tanaka, T. (Toshiko), Tare, A. (Archana), Teumer, A. (Alexander), Tönjes, A. (Anke), Uh, H.-W. (Hae-Won), Vandenput, L. (Liesbeth), Vasan, R.S. (Ramachandran Srini), Völker, U. (Uwe), Wallaschofski, H. (Henri), Willems, S.M. (Sara), Zhang, C. (Cuilin)   +85 more
core   +1 more source

Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington’s disease knock-in striatal cells [PDF]

, 2014
Akt, protein kinase B; ARE, antioxidant response element; Erk, extracellular signal-regulated kinase; CBP, CREB-binding protein; CREB, cAMP response-element (CRE) binding protein; CDK, cyclin-dependent kinase; DHE, dihydroethidium; Drp1, dynamin-related ...
Oliveira, Ana M., Oliveira, Catarina R., Rego, A. Cristina, Ribeiro, Márcio, Rosenstock, Tatiana R.   +4 more
core   +1 more source