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Expression of insulin-like growth factor binding protein-3 in HELLP syndrome [PDF]

open access: yesBMC Pregnancy and Childbirth, 2023
Objective To investigate the expression of insulin-like growth factor binding protein-3(IGFBP-3) in HELLP syndrome and its possible role in the pathogenesis of this disease. Methods 1) 87 subjects were enrolled, including 29 patients with HELLP syndrome,
Li Wei, Zhou Liping, Kang Suya
doaj   +4 more sources

Insulin-like Growth Factor Binding Protein 3 Increases Mouse Preimplantation Embryo Cleavage Rate by Activation of IGF1R and EGFR Independent of IGF1 Signalling [PDF]

open access: goldCells, 2022
The viability of embryos cultured in vitro is poor compared to those that develop in vivo. The lack of maternally derived growth factors in vitro may contribute to this problem.
Charmaine J. Green   +4 more
doaj   +4 more sources

In silico interaction of insulin-like growth factor binding protein 3 with insulin-like growth factor 1 [PDF]

open access: yesResearch in Pharmaceutical Sciences, 2018
Insulin-like growth factor binding protein-3 (IGFBP-3) is a vital protein exist in circulation which interacts with high affinity to insulin-like growth factor (IGFs) altering their activities.
Elham Jafari   +6 more
doaj   +5 more sources

Correlation of tri-ponderal mass index with insulin-like growth factor-I and insulin-like growth factor binding protein-3 in children and adolescents [PDF]

open access: diamondAnnals of Pediatric Endocrinology & Metabolism
Purpose We aimed to investigate the relationship between the tri-ponderal mass index (TMI), a new indirect measure of fat mass, and insulin-like growth factor (IGF)-I/IGF binding protein (IGFBP)-3.
Iee Ho Choi, Sun-Young Kim, Minsun Kim
doaj   +4 more sources

Insulin-Like Growth Factor Binding Protein-3 Binds to Histone 3. [PDF]

open access: yesInt J Mol Sci, 2021
Insulin-like growth factor (IGF) binding protein-3 (IGFBP-3) is an essential protein that regulates cellular processes such as cell proliferation, apoptosis, and differentiation. It is known to bind with several proteins to carry out various cellular functions. In this study, we report for the first time that IGFBP-3 is a histone 3 (H3) binding protein.
Bhardwaj A   +3 more
europepmc   +4 more sources

Reference Ranges of Serum Insulin-Like Growth Factor-I and Insulin-Like Growth Factor Binding Protein-3: Results from a Multicenter Study in Healthy Korean Adults [PDF]

open access: yesEndocrinology and Metabolism, 2020
Insulin-like growth factor-I (IGF-I) plays a pivotal role in the diagnosis and treatment of growth hormone (GH) excess or deficiency. The GH study group of the Korean Endocrine Society aims to establish the Korean reference ranges of serum IGF-I and ...
In-Kyung Jeong   +6 more
doaj   +2 more sources

Relationship of Serum Total Insulin-Like Growth Factor Binding Protein-3 with Insulin-Like Growth Factor-I and Glucose Tolerance in Korean Children and Adolescents [PDF]

open access: yesInternational Journal of Endocrinology, 2021
Insulin is important in glucose metabolism. However, insulin-like growth factor binding protein (IGFBP) also plays an important role in glucose homeostasis, although the IGF-independent role of IGFBP-3 in the glucose intolerance state is poorly ...
Sun-Young Kim   +3 more
doaj   +2 more sources

Nuclear actions of insulin-like growth factor binding protein-3. [PDF]

open access: yesGene, 2015
In addition to its actions outside the cell, cellular uptake and nuclear import of insulin-like growth factor binding protein-3 (IGFBP-3) has been recognized for almost two decades, but knowledge of its nuclear actions has been slow to emerge. IGFBP-3 has a functional nuclear localization signal and interacts with the nuclear transport protein importin-
Baxter RC.
europepmc   +4 more sources

Expression and pathogenesis of insulin-like growth factor-1 and insulin-like growth factor binding protein 3 in a mouse model of ulcerative colitis [PDF]

open access: yesHeliyon
Background and aim: Insulin-like growth factor-1 may be involved in the epithelial-to-mesenchymal transition process. It can mitigate adverse effects when interacting with insulin-like growth factor binding protein 3.
Weihua Wang   +7 more
doaj   +2 more sources

Insulin-like-growth-factor-binding-protein-3 (IGFBP-3) contrasts melanoma progression in vitro and in vivo. [PDF]

open access: goldPLoS ONE, 2014
Insulin-like-factor-binding-protein 3 (IGFBP-3) is known to modulate the activity of insulin-like growth factors (IGFs) besides having a number of IGF-independent effects on cell growth and survival. IGFBP-3 has been reported to decrease significantly in
Antimo Naspi   +12 more
doaj   +3 more sources

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