Results 261 to 270 of about 207,610 (292)

Insulin-like growth factors sustain insulin-like growth factor-binding protein-5 expression in osteoblasts

American Journal of Physiology-Endocrinology and Metabolism, 1998
Insulin-like growth factors (IGFs) I and II are considered to be autocrine regulators of bone cell function. Recently, we demonstrated that IGF-I induces IGF-binding protein-5 (IGFBP-5) expression in cultures of osteoblast-enriched cells from 22-day fetal rat calvariae (Ob cells).
B, Gabbitas, E, Canalis
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Insulin-like growth factor-I and insulin-like growth factor-binding protein in the toad, Bufo woodhousei

General and Comparative Endocrinology, 1990
Molecular weight characteristics and plasma concentrations of insulin-like growth factor-I (IGF-I) and its binding protein (IGF-BP) were investigated in the toad, Bufo woodhousei. IGF-I and IGF-BP were measured by radioimmunoassay (RIA, Kd = 0.37 +/- 0.04 ng/ml) and charcoal-separated ligand binding assay, respectively, in male toad plasma and adult ...
M K, Pancak-Roessler, P D, Lee
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The Expression of Insulin-like Growth Factor and Insulin-like Growth Factor Binding Protein mRNAs in Mouse Placenta

Placenta, 2006
Insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs) are paracrine regulators of tissue growth and development, and are expressed at the sites of biological action. To study the role of the IGFs and IGFBPs in mouse placental development, we determined the temporal and spatial expression patterns of the mRNAs at embryonic days 10.5 to 18.
Carter, Anthony M.; id_orcid 0000-0002-8359-2085, Nygard, K., Mazzuca, D.M., Han, V.K.M.   +3 more
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Insulin-like growth factor 2 and insulin-like growth factor binding protein 2 expression in hepatoblastoma

Human Pathology, 1995
The expression of insulin-like growth factor 2 (IGF2) and insulin-like growth factor binding protein 2 (IGFBP2) in 11 cases of hepatoblastoma was studied by means of in situ mRNA hybridization using digoxigenin (DIG)-labeled riboprobes. The results showed that both IGF2 and IGFBP2 transcripts are present in hepatoblastoma and that their expression is ...
S N, Akmal, K, Yun, J, MacLay, Y, Higami, T, Ikeda   +4 more
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Glycosaminoglycan binding characteristics of the insulin-like growth factor-binding proteins

Journal of Molecular Endocrinology, 1994
Interactions between the IGF-binding proteins (IGFBPs) and glycosaminoglycans (GAGs) such as heparin may be involved in the regulatory control of IGF exerted by the IGFBPs at the level of the extracellular matrix and capillary endothelium, although the precise mechanisms of this remain uncertain.
S C, Hodgkinson, J R, Napier, G S, Spencer, J J, Bass   +3 more
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Insulin-like growth factors, insulin-like growth factor-binding proteins, insulin-like growth factor-binding protein-3 protease, and growth hormone-binding protein in lipodystrophic Human Immunodeficiency Virus-infected patients

Metabolism, 2004
Human immunodeficiency virus (HIV)-lipodystrophy is associated with impaired growth hormone (GH) secretion. It remains to be elucidated whether insulin-like growth factors (IGFs), IGF-binding proteins (IGFBPs), IGFBP-3 protease, and GH-binding protein (GHBP) are abnormal in HIV-lipodystrophy.
Steen B, Haugaard, Ove, Andersen, Birgitte R, Hansen, Hans, Orskov, Ulrik B, Andersen, Sten, Madsbad, Johan, Iversen, Allan, Flyvbjerg   +7 more
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Role of Growth-Hormone and Insulin-Like Growth-Factor-Binding Proteins

Hormone Research, 2008
Some peptide hormones are associated with specific, high-affinity plasma proteins. The major binding protein (BP) for growth hormone (GH) in humans is a circulating fragment of the GH membrane receptor, consisting of the hydrophilic, extracellular portion of that transmembrane glycoportein.
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Insulin‐like growth factor binding proteins and their regulation

Acta Paediatrica, 1994
R G, Rosenfeld, H, Pham, P, Cohen, P, Fielder, S E, Gargosky, H, Muller, L, Nonoshita, Y, Oh   +7 more
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The insulin-like growth factor-binding protein superfamily

Growth Hormone & IGF Research, 2000
R G, Rosenfeld, V, Hwa, E, Wilson, S R, Plymate, Y, Oh   +4 more
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Cellular Actions of the Insulin-Like Growth Factor Binding Proteins

Endocrine Reviews, 2002
Sue M Firth, Robert C Baxter, Firth Sue M   +2 more
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