Results 291 to 300 of about 590,806 (400)

Physiological Roles of Pituitary Insulin-Like Growth Factor I -Intrapituitary Regulatory System- [PDF]

, 2003
Honda, Junichi, Manabe, Yoshie, Matsumura, Ryusei, Takahashi, Sumio, Takeuchi, Sakae   +4 more
core  

Gut Microbiota Modulates Obesity‐Associated Skeletal Deterioration Through Macrophage Aging and Grancalcin Secretion

Advanced Science, EarlyView.
Obese gut‐microbiota derived lipopolysaccharides (LPS) induce bone marrow macrophage senescence and GCA secretion via activating TLR4/NF‐κB/MAPKs pathway. Clinically, obese patients are associated with higher serum GCA levels. Mice with depletion of GCA gene show resistance to skeletal deterioration caused by obesity and LPS‐induced chronic ...
Min Huang, Mei Huang, Ling Liu, Fang Yang, Chen He, Yu‐Chen Sun, Yu‐Rui Jiao, Xiang Tang, Jing Hou, Kai‐Xuan Chen, Wen‐Zhen He, Jie Wei, Hui‐Ling Chen, Xia Li, Chao Zeng, Guang‐Hua Lei, Chang‐Jun Li   +16 more
wiley   +1 more source

Endoplasmic reticulum stress PERK-ATF4-CHOP pathway is involved in non-alcoholic fatty liver disease in type 1 diabetic rats: The rescue effect of treatment exercise and insulin-like growth factor I. [PDF]

Heliyon
Mohammadpour-Asl S, Roshan-Milani B, Roshan-Milani S, Saboory E, Ghobadian B, Chodari L.   +5 more
europepmc   +1 more source

Effect of a null mutation of the insulin-like growth factor I receptor gene on growth and transformation of mouse embryo fibroblasts

Molecular and Cellular Biology, 1994
C. Sell, G. Duménil, C. Deveaud, M. Miura, D. Coppola, T. Deangelis, R. Rubin, A. Efstratiadis, R. Baserga   +8 more
semanticscholar   +1 more source

Parvalbumin Interneuron‐Dependent Hippocampal Neurogenesis Evoked by Prolonged Rhythmic Light Flicker

Advanced Science, EarlyView.
This study demonstrates that prolonged rhythmic 40 Hz light flicker enhances spatial learning by stimulating PV interneuron‐dependent neurogenesis. The light flicker selectively activates PV interneurons, which enhances GABAergic support for the integration of immature neurons in the adult dentate gyrus.
Hai Yan, Yunxuan Wang, Xufan Deng, Shiyu Wu, Yifan Pan, Jun Du, Mei Yu, Bo Liu, Huimei Wang, Zhengyu Zhang, Jinghong Chen, Shuifa Chen, Yizheng Wang, Tara Walker, Perry Bartlett, Jun Ju, Sheng‐Tao Hou   +16 more
wiley   +1 more source

Delirium, insulin-like growth factor I, growth hormone in older inpatients. [PDF]

World J Psychiatry, 2020
Adamis D, Coada I, Eikelenboom P, Chu CS, Finn K, Melvin V, Williams J, Meagher DJ, McCarthy G.   +8 more
europepmc   +1 more source

Role of insulin-like growth factors and the type I insulin-like growth factor receptor in the estrogen-stimulated proliferation of human breast cancer cells.

, 1990
Alistair Stewart, Michael D. Johnson, Felicity E. B. May, B R Westley   +3 more
openalex   +1 more source

Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer

Advanced Science, EarlyView.
Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska, Paula Allepuz‐Fuster, Chloé Maurizy, Alexandre Hego, Sandra Ormenese, Quentin Lion, Arnaud Blomme, Pierre Close, Arnaud Lavergne, Latifa Karim, Marc Thiry, Ivan Nemazanyy, Roopesh Krishnankutty, Jair Marques Jr, Alex von Kriegsheim, Nathaniel F. Henneman, Ganna Panasyuk, Kateryna Shostak, Alain Chariot   +18 more
wiley   +1 more source

The cysteine-rich domains of the insulin and insulin-like growth factor I receptors are primary determinants of hormone binding specificity. Evidence from receptor chimeras.

, 1990
Thomas A. Gustafson, William J. Rutter
openalex   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

Advanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai, Yuxin Zhao, Zilong Li, Liping Xiao, Yifan Wu, Shiya Wang, Qian Liu, Yida Ye, Yuxuan Guo, Donghui Zhang   +9 more
wiley   +1 more source