Results 31 to 40 of about 14,458,916 (288)

Investigation of insulin-like growth factors/insulin-like growth factor binding proteins regulation in metabolic syndrome patients

BMC Research Notes, 2019
Objective The insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are thought to play a significant role in metabolic pathways and glucose metabolism.
Somayeh Pouriamehr, Haleh Barmaki, Mozhdeh Rastegary, Farzaneh Lotfi, Mohsen Nabi Afjadi   +4 more
doaj   +1 more source

Analysis of Insulin-like Growth Factors and Insulin-like Growth Factor I Receptor Expression in Renal Cell Carcinoma [PDF]

American Journal of Clinical Pathology, 2004
The expression of insulin-like growth factors I (IGF-I) and II (IGF-II) and insulin-like growth factor-I receptor (IGF-IR) was studied in 137 clear cell, 23 chromophobe, and 20 papillary renal cell carcinomas (RCCs) using a tissue microarray technique. IGF-I immunoreactivity was detected in 110 (82.1%) of 134 clear cell, 8 (36%) of 22 chromophobe, and ...
Schips, Luigi, Zigeuner, R, Ratschek, M, Rehak, P, Ruschoff, J, Langner, C   +5 more
openaire   +2 more sources

Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland [PDF]

, 2005
We have demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) production by mammary epithelial cells increases dramatically during forced involution of the mammary gland in rats, mice and pigs.
Beattie, J, Whitelaw C. B. A., ACCORSI, PIER ATTILIO, Hurley, W, Boutinaud, M, Kolb A., Allan G. A., Tonner, E, Wilde, C J, Boutinaud M., Wilde C. J., Beattie J., Accorsi, P A, Flint, D J, Flint D. J., Tonner E., Whitelaw, C B A, Hurley W., Kolb, A F, Allan, G J   +19 more
core   +1 more source

Molecular evolution and functional characterization of Drosophila insulin-like peptides [PDF]

, 2010
Multicellular animals match costly activities, such as growth and reproduction, to the environment through nutrient-sensing pathways. The insulin/IGF signaling (IIS) pathway plays key roles in growth, metabolism, stress resistance, reproduction, and ...
Andrews, T Daniel, Partridge, Linda, Grönke, Sebastian, Broughton, Susan, Clarke, David-Francis   +4 more
core   +5 more sources

MiR-205 serves as a prognostic factor and suppresses proliferation and invasion by targeting insulin-like growth factor receptor 1 in human cervical cancer

Tumor Biology, 2017
MicroRNAs are a kind of small and non-coding RNAs, which have been demonstrated to play an important role in the progression of human cervical cancer.
Hui Pang, Xiuying Yue
doaj   +1 more source

Cloning and expression of full-length human insulin-like growth factor binding protein 3 (IGFBP3) in the Escherichia coli

Advanced Biomedical Research, 2015
Background: The effect of the growth hormone on target cells is mediated by the insulin-like growth factor 1 (IGF-1). IGF-1 binds to the insulin-like growth factor binding proteins (IGFBPs) in blood and biological fluids.
Emad Khodadadi, Mojtaba Panjepour, Mahdi Abbasian, Zahra Khalili Broujeni, Mohammad Reza Mofid   +4 more
doaj   +1 more source

Insulin-like growth factor-II: new roles for an old actor

Frontiers in Endocrinology, 2012
IGF-II, traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator.
Stefano eCianfarani
doaj   +1 more source

The contradictions of the insulin-like growth factor 1 receptor [PDF]

Oncogene, 2000
In recent years, the type 1 insulin-like growth factor receptor (IGF-IR) has emerged as a receptor that plays a very important role in the growth of cells, both in vivo and in vitro. The ability of the IGF-IR to induce mitogenesis and to promote survival of cells against a variety of apoptotic agents is well documented.
openaire   +2 more sources

IGF2R (insulin-like growth factor 2 receptor) [PDF]

, 2004
Review on IGF2R (insulin-like growth factor 2 receptor), with data on DNA, on the protein encoded, and where the gene is ...
Killian, JK
core   +1 more source

IGF1R (insulin-like growth factor 1 receptor) [PDF]

, 2009
Review on IGF1R (insulin-like growth factor 1 receptor), with data on DNA, on the protein encoded, and where the gene is ...
Bentov, Y, Werner, H
core   +1 more source