Results 131 to 140 of about 22,902,059 (175)

Biological role and clinical significance of insulin-like peptide 3

Current Opinion in Endocrinology, Diabetes & Obesity, 2011
Insulin-like peptide 3 (INSL3) is the subject of a fast expanding literature reflecting increasing clinical application, particularly as a diagnostic parameter. This review summarizes the recent INSL3 literature published within the last 12-18 months.Significant inroads have been made to understand how INSL3 is working in testicular descent.
Ivell, R., Anand Ivell, R.
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In Vitro Degradation of Insulin-like Peptide 3 by Insulin-degrading Enzyme

The Protein Journal, 2010
Insulin-like peptide 3 (INSL3) is an insulin superfamily peptide hormone, primarily expressed in the testes and playing a key role in the fetus testes descent and suppression of male germ cell apoptosis. Insulin-degrading enzyme (IDE) is a zinc-metalloprotease, responsible for in vivo degradation of insulin, Abeta, and other peptide hormones.
Wei-Jie, Zhang, Xiao, Luo, Zhan-Yun, Guo
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Correlation between insulin‐like peptide 3 and appendix testis length in congenital cryptorchidism

Journal of Paediatrics and Child Health, 2020
AimThe appendix testis (AT) is a vestigial remnant of Müller's paramesonephric duct. Insulin‐like 3 hormone (INSL3) is produced in the Leydig cells of the testis. We investigated the possible correlation between AT length and plasma INSL3 concentrations in patients with congenital cryptorchidism (CCO) and patients with hydrocele, who served as controls.
Antonios Panagidis, Eirini Kostopoulou, Andrea Paola Rojas Gil, Xenophon Sinopidis, Helen Kourea, Spyros Skiadopoulos, George Georgiou, Bessie E Spiliotis   +7 more
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Insulin-Like Peptide 3 in Leydig Cells

2007
Richard Ivell and Ross A.D.
Ivell, R., Bathgate, R.
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Longitudinal assessment of circulating insulin-like peptide 3 levels in healthy peripubertal girls

Fertility and Sterility, 2015
To elucidate the natural course of circulating insulin-like peptide 3 (INSL3) levels according to puberty as well as its relation to other reproductive hormones.Population-based cohort study.Not applicable.Healthy peripubertal girls (n = 10) examined every 6 months; total number of examinations was 84; median (range) per girl: 9 (4-10), including ...
Hagen, Casper P, Mieritz, Mikkel G, Nielsen, John E, Anand-Ivell, Ravinder, Ivell, Richard, Juul, Anders   +5 more
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Synthesis, conformation, receptor binding and biological activities of monobiotinylated human insulin‐like peptide 3*

The Journal of Peptide Research, 2004
Abstract:  Biotin‐avidin immobilization has been routinely used as a tool to study peptide–receptor and peptide–antibody interactions. Biotinylated peptides can also be employed to localize cells that express the peptides’ receptor, and to analyse ligand‐receptor binding.
P, Fu, S, Layfield, T, Ferraro, H, Tomiyama, J, Hutson, L, Otvos, G W, Tregear, R A D, Bathgate, J D, Wade   +8 more
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Immunohistochemical Localization of Relaxin‐Like Factor/Insulin‐Like Peptide‐3 in the Bovine Corpus Luteum

Annals of the New York Academy of Sciences, 2005
Abstract: Relaxin‐like factor/insulin‐like peptide (INSL)‐3 is highly expressed in the bovine corpus luteum throughout the estrous cycle and pregnancy. Demonstration of translation of the relaxin‐like factor message was previously shown for the follicle but not the corpus luteum.
Nichols, N., Binta, H., Fields, P., Drost, M., Chang, S., Ivell, R., Fields, M.   +6 more
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