Results 291 to 300 of about 339,703 (317)

Design, synthesis and pharmacological evaluation of cyclic mimetics of the insulin‐like peptide 3 (INSL3) B‐chain

Journal of Peptide Science, 2006
AbstractInsulin‐like peptide 3 (INSL3) is a peptide hormone belonging to the relaxin‐insulin superfamily of peptides that plays important roles in testes descent, oocyte maturation and the control of male germ cell apoptosis. These actions are mediated via a specific G‐protein coupled receptor, LGR8.
Fazel, Shabanpoor, Ross A D, Bathgate, Mohammed Akhter, Hossain, Eleni, Giannakis, John D, Wade, Richard A, Hughes   +5 more
openaire   +2 more sources

Role of the intra-A-chain disulfide bond of insulin-like peptide 3 in binding and activation of its receptor, RXFP2

Peptides, 2010
INSL3 is a member of the insulin-IGF-relaxin superfamily and plays a key role in male fetal development and in adult germ cell maturation. It is the cognate ligand for RXFP2, a leucine-rich repeat containing G-protein coupled receptor. To date, and in contrast to our current knowledge of the key structural features that are required for the binding of ...
Suode, Zhang, Richard A, Hughes, Ross A D, Bathgate, Fazel, Shabanpoor, M Akhter, Hossain, Feng, Lin, Bianca, van Lierop, Andrea J, Robinson, John D, Wade   +8 more
openaire   +2 more sources

Changes in plasma concentrations of insulin-like peptide 3 and testosterone from birth to pubertal age in beef bulls

Theriogenology, 2011
The objectives were to: (1) develop an enzyme immunoassay (EIA) for insulin-like peptide 3 (INSL3) or relaxin-like factor (RLF) in bovine plasma; (2) investigate changes of plasma INSL3 concentrations from birth to pubertal age of beef bulls; and (3) compare changes in plasma concentrations of INSL3, testosterone, and LH.
N, Kawate, A, Ohnari, I N, Pathirana, M, Sakase, E E, Büllesbach, M, Takahashi, T, Inaba, H, Tamada   +7 more
openaire   +2 more sources

Mouse Mutants of Relaxin, Insulin-Like 3 Peptide and their Receptors

Current Medicinal Chemistry-Immunology, Endocrine & Metabolic Agents, 2005
openaire   +1 more source

Insulin-Like Peptide 3 (INSL3)

2009
openaire   +1 more source

Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and β-cell function in type 2 diabetes: a parallel-group study

Lancet, The, 2002
Sten Madsbad, Jens J Holst Dmsci
exaly  

Involvement of the adenylyl cyclase signaling system in the action of insulin and mollusk insulin-like peptide

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, 1995
Alexander O Shpakov
exaly  

Reduced insulin clearance contributes to the increased insulin levels after administration of glucagon-like peptide 1 in mice

Diabetologia, 2005
Bo Ahrén, Karl Thomaseth
exaly  

Insulin Regulates Glucagon-Like Peptide-1 Secretion from the Enteroendocrine L Cell

Endocrinology, 2009
Gareth E Lim, Patricia Brubaker
exaly  

Secretion of the Incretin Hormones Glucagon-Like Peptide-1 and Gastric Inhibitory Polypeptide Correlates with Insulin Secretion in Normal Man Throughout the Day

Scandinavian Journal of Gastroenterology, 1996
Jens J Holst Dmsci
exaly