Results 191 to 200 of about 90,101 (333)
Advanced Science, EarlyView.This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu +10 more
wiley +1 more source
Mastoparan-Induced Insulin Secretion from Insulin-Secreting βTC3 and INS-1 Cells: Evidence for Its Regulation by Rho Subfamily of G Proteins [PDF]
, 2003 Rajesh Amin +6 more
openalex +1 more source
Advanced Science, EarlyView.The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye +16 more
wiley +1 more source
Oxidative Stress Is a Mediator of Glucose Toxicity in Insulin-secreting Pancreatic Islet Cell Lines [PDF]
, 2004 Lan Wu +6 more
openalex +1 more source
Advanced Science, EarlyView.Irisin is a crucial plasma biomarker and promising therapeutic target that reflects disease severity, pulmonary vascular remodeling status and clinical outcome in patients with pulmonary arterial hypertension (PAH). As a novel protective factor, irisin is downregulated in PAH. By ubiquitination, irisin promotes Enolase 1 degradation and suppresses cell
Na Sun +15 more
wiley +1 more source
Insulin-like growth factor binding protein-3 is a novel mediator of apoptosis in insulin-secreting cells [PDF]
, 2004 Melanie Shim +5 more
openalex +1 more source
Advanced Science, EarlyView.Elevated lactate in diabetes activates the GPR132‐Src pathway in macrophages, inducing macrophage senescence and further enhancing foam cell formation. This mechanism exacerbates atherosclerotic progression. Abstract Diabetes is widely acknowledged as a significant risk factor for atherosclerosis, facilitating plaque formation through various ...
Xiaofeng Ge +10 more
wiley +1 more source
Mechanisms of Dense Core Vesicle Recapture following “Kiss and Run” (“Cavicapture”) Exocytosis in Insulin-secreting Cells [PDF]
, 2004 Takashi Tsuboi +2 more
openalex +1 more source
Correction: Generation and selection of pluripotent stem cells for robust differentiation to insulin-secreting cells capable of reversing diabetes in rodents. [PDF]
PLoS One, 2019 Southard SM, Kotipatruni RP, Rust WL.
europepmc +1 more source