Results 221 to 230 of about 98,089 (330)

β-Cells are not uniform after all-Novel insights into molecular heterogeneity of insulin-secreting cells. [PDF]

Diabetes Obes Metab, 2017
Avrahami D, Wang YJ, Klochendler A, Dor Y, Glaser B, Kaestner KH.   +5 more
europepmc   +1 more source

Amantadine and sparteine inhibit ATP‐regulated K‐currents in the insulin‐secreting β‐cell line, HIT‐T15 [PDF]

, 1991
Frances M. Ashcroft, Amanda Kerr, John S. Gibson, Beatrice A. Williams   +3 more
openalex   +1 more source

IL‐4/STAT6‐signaling Influences Local Inflammation and Regeneration Processes During Acute Pancreatitis and Promotes Fibrosis by a Direct Activation of Pancreatic Fibroblasts During Chronic Pancreatitis

Advanced Science, EarlyView.
IL‐4/IL‐13/STAT6 signaling plays a crucial for the suppression of pro‐inflammation during acute pancreatitis and supports acinar cell regeneration but has only minor impact on fibrogenesis during chronic form of the disease. IL‐4/IL‐13 induce the expression of certain collagens directly in pancreatic fibroblasts via STAT6 activation, whereas ...
ElSheikh H, Salvers A, Piesker J, Buchholz S, Lange R, Ameling S, Steil L, Hammer E, Homuth G, Völker U, Bröker BM, Weiss FU, Sendler M, Glaubitz J   +13 more
wiley   +1 more source

Overexpression of sphingosine-1-phosphate lyase protects insulin-secreting cells against cytokine toxicity. [PDF]

J Biol Chem, 2017
Hahn C, Tyka K, Saba JD, Lenzen S, Gurgul-Convey E.   +4 more
europepmc   +1 more source

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Reinterpretation of the localization of the ATP binding cassette transporter ABCG1 in insulin-secreting cells and insights regarding its trafficking and function. [PDF]

PLoS One, 2018
Harris MT, Hussain SS, Inouye CM, Castle AM, Castle JD.   +4 more
europepmc   +1 more source

Activity-Dependent Cav1.2 Cluster Surface Expression in Insulin-Secreting Cells [PDF]

, 2010
Enming Zhang, Paweł Buda, Taman Mahdi, Thomas Reinbothe, Jörg Striessnig, Erik Renström   +5 more
openalex   +1 more source

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

Manufacturing of Insulin-Secreting Spheroids with the RIN-5F Cell Line Using a Shaking Culture Method

, 2010
Dong Jin Joo, J.Y. Kim, J.I. Lee, Jae‐Hee Jeong, Y. Cho, Man Ki Ju, Kyu Ha Huh, Myoung Soo Kim, Yu Seun Kim   +8 more
openalex   +2 more sources

Effects of Glucose and Amino Acids on Free ADP in βHC9 Insulin-Secreting Cells [PDF]

, 2001
Peter Ronner, C. Maik Naumann, Edward Friel   +2 more
openalex   +1 more source