Results 121 to 130 of about 1,879,389 (356)

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Insulin receptor tyrosine kinase substrate links theE. coliO157:H7 actin assembly effectors Tir and EspF_Uduring pedestal formation

, 2009
Didier Vingadassalom, Arūnas Kazlauskas, Brian Skehan, Hui‐Chun Cheng, Loranne Magoun, Douglas R. Robbins, Michael K. Rosen, Kalle Saksela, John M. Leong   +8 more
openalex   +1 more source

Repletion of Atypical Protein Kinase C following RNA Interference-mediated Depletion Restores Insulin-stimulated Glucose Transport [PDF]

, 2006
Mini P. Sajan, José Rivas, Pengfei Li, Mary L. Standaert, Robert V. Farese   +4 more
openalex   +1 more source

Fibrillar Bundles as Fibrous Filler Materials for Attaining Cell Anisotropy in Bioprinting

Advanced Healthcare Materials, EarlyView.
Fibrillar bundles are introduced as a bioprintable additive that enables robust and scalable cellular alignment within 3D constructs through flow‐induced orientation during extrusion. These fibers support strong cell adhesion and polarization across various cell types and significantly enhance myotube alignment in Gelatine‐Methacryloyl (GelMA ...
Sven Heilig, Zan Lamberger, Lys Sprenger, Vivien Priebe, Camilla Mussoni, Denitsa Docheva, Kristina Andelovic, Jürgen Groll, Sahar Salehi, Gregor Lang, Matthias Ryma   +10 more
wiley   +1 more source

Safety of Insulin Lispro and a Biosimilar Insulin Lispro When Administered Through an Insulin Pump [PDF]

, 2018
James Thrasher, Howard K. Surks, Irene Nowotny, Suzanne Pierre, Baerbel Rotthaeuser, Karin Wernicke‐Panten, Satish K. Garg   +6 more
openalex   +1 more source

Evaluation of glycaemic profile variability as a basis for insulin therapy strategy in pregnant women with type 1 diabetes [PDF]

, 2020
A. V. Tiselko, Maria I. Yarmolinskaya, Elena V. Misharina, Yu. P. Milyutina   +3 more
openalex   +1 more source

TLR4 links innate immunity and fatty acid-induced insulin resistance.

Journal of Clinical Investigation, 2006
Hang Shi, M. Kokoeva, K. Inouye, Iphigenia Tzameli, Huali Yin, J. Flier   +5 more
semanticscholar   +1 more source

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Triazine‐Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Novel photo‐clickable triazine‐trione thermosets can be shaped and cured under mild conditions, including room and physiological temperatures. These materials are biocompatible and support osteogenic differentiation of bone marrow–derived mesenchymal stem cells on their surface.
Åshild Johansen, Shuntaro Yamada, Daniel J. Hutchinson, Mohammed A. Yassin, Samih Mohamed‐Ahmed, Cecilie Gjerde, Michael Malkoch, Kamal Mustafa   +7 more
wiley   +1 more source

Editorial: Cell Signaling in Tumors of Endocrine and Endocrine-Responsive Tissues

Frontiers in Endocrinology, 2019
Claire Perks, Angela Hague
doaj   +1 more source