Autoantibodies directed against insulin receptor during the course of Castleman disease: a new case reaffirming autoimmune hypoglycemia as a relapse warning signal [PDF]
This case study presents the case of a 54-year-old human immunodeficiency virus (HIV)-positive male who developed type B insulin resistance syndrome (TBIRS) in conjunction with a relapse of human herpesvirus 8 (HHV8)-positive multicentric Castleman ...
Xavier Jannot+6 more
doaj +2 more sources
Use of the SGLT2 inhibitor canagliflozin for control of refractory equine hyperinsulinemia and laminitis [PDF]
Background: Hyperinsulinemia associated with pituitary pars intermedia dysfunction (PPID) and/or equine metabolic syndrome (EMS) is well documented to put horses at high risk of laminitis.
Eleanor M. Kellon, Kathleen M. Gustafson
doaj +1 more source
Molecular and Cellular Bases of Lipodystrophy Syndromes
Lipodystrophy syndromes are rare diseases originating from a generalized or partial loss of adipose tissue. Adipose tissue dysfunction results from heterogeneous genetic or acquired causes, but leads to similar metabolic complications with insulin ...
Jamila Zammouri+20 more
doaj +1 more source
Hypertriglyceridemia in equines with refractory hyperinsulinemia treated with SGLT2 inhibitors
Background: Sodium-Glucose CoTransporter-2 [SGLT2] inhibitors, the -flozin group of drugs, which block glucose reuptake in the renal proximal tubule, are being increasingly used off-label to treat horses with refractory hyperinsulinemia. After two years
Eleanor M. Kellon, Kathleen M. Gustafson
doaj +1 more source
Heterozygous loss-of-function variants of the glucokinase (GCK) gene are responsible for a subtype of maturity-onset diabetes of the young (MODY). GCK-MODY is characterized by a mild hyperglycemia, mainly due to a higher blood glucose threshold for ...
José Timsit+14 more
doaj +1 more source
Possible dysmetabolic hyperferritinemia in hyperinsulinemic horses [PDF]
Background: Hyperinsulinemia associated with equine metabolic syndrome (EMS) and pituitary pars intermedia dysfunction (PPID) is a risk factor for laminitis.
Eleanor M. Kellon, Kathleen M. Gustafson
doaj +1 more source
Dunnigan syndrome, or Familial Partial Lipodystrophy type 2 (FPLD2; ORPHA 2348), is a rare autosomal dominant disorder due to pathogenic variants of the LMNA gene. The objective of the French National Diagnosis and Care Protocol (PNDS; Protocole National
H. Mosbah+36 more
doaj +1 more source
Background In humans and animal models, excessive intake of dietary fat, fructose and cholesterol has been linked to the development of non-alcoholic fatty liver disease (NAFLD). However, the individual roles of the dietary components remain unclear.
Victoria Svop Jensen+7 more
doaj +1 more source
Insulin infusion sets associated with adverse events: strategies for improved diabetes education
IntroductionInsulin Infusion Sets (IIS) play a crucial role in ensuring the safe delivery of insulin through a Continuous Subcutaneous Insulin Infusion (CSII) for individuals with Type 1 Diabetes (T1D). Recent advancements in therapy have highlighted the
Ana Lucia Domingues Neves+12 more
doaj +1 more source
Prevalence and Incidence of Insulin Dependent Diabetes Mellitus (IDDM) in Fars province in the South of Iran, 2016-17: An Insurance Archived-Prescription-based Study [PDF]
Background: Insulin-dependent diabetes mellitus (IDDM) or type 1 diabetes mellitus (T1DM) is known as a chronic autoimmune disease with an increasing prevalence and incidence.
Sanaz Amiri+3 more
doaj +1 more source