Results 191 to 200 of about 1,879,389 (356)

Human gut microbes impact host serum metabolome and insulin sensitivity

Nature, 2016
H. Pedersen, Valborg Gudmundsdottir, H. Nielsen, Tuulia Hyotylainen, T. Nielsen, B. Jensen, K. Forslund, F. Hildebrand, Edi Prifti, G. Falony, E. Chatelier, F. Levenez, J. Doré, I. Mattila, D. Plichta, Päivi Pöhö, L. Hellgren, Manimozhiyan Arumugam, S. Sunagawa, S. Vieira-Silva, T. Jørgensen, J. Holm, K. Trošt, MetaHIT consortium, K. Kristiansen, S. Brix, J. Raes, Jun Wang, T. Hansen, P. Bork, S. Brunak, M. Orešič, S. Ehrlich, O. Pedersen   +33 more
semanticscholar   +1 more source

Research Progress in Wearable Microneedle Sensors for Health Analysis

Advanced Sensor Research, EarlyView.
Wearable biosensors are transforming personal healthcare by enabling minimally invasive, molecular‐level monitoring. Emerging electrochemical microneedle sensors can detect analytes in interstitial fluid, enabling painless extraction and real‐time tracking.
Adnan Zameer, Yang Guo, Hongda Wang, Qiang Zhang   +3 more
wiley   +1 more source

Exogenous insulin autoimmune syndrome: a case report and literature review. [PDF]

Front Endocrinol (Lausanne)
Gao Y, Wang N, Huang Z, Bai N.
europepmc   +1 more source

Ileal interposition surgery-induced improvement of hyperglycemia and insulin resistance in Goto-Kakizaki rats by upregulation of TCF7L2 expression

, 2013
Xu Sun, Mao‐Min Song, Rixing Bai, Shi Cheng, Ying Xing, Huisheng Yuan, Pilin Wang, Lisa Zhou   +7 more
openalex   +2 more sources

Phase‐Separation of YAP Mediates AJUBA Super Enhancer Activation to Promote Aberrant Mitosis in Breast Cancer

Advanced Science, EarlyView.
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang, Qingwen Huang, Zhuo Chen, Weijian Meng, Hongliang Dong, Zhihong Qi, Liang Liu, Jie Shen, Daxing Xie   +8 more
wiley   +1 more source

Intensive insulin therapy and pentastarch resuscitation in severe sepsis.

New England Journal of Medicine, 2008
F. Brunkhorst, C. Engel, F. Bloos, A. Meier‑Hellmann, M. Ragaller, N. Weiler, O. Moerer, M. Gruendling, M. Oppert, S. Grond, D. Olthoff, U. Jaschinski, S. John, R. Rossaint, T. Welte, M. Schaefer, P. Kern, E. Kuhnt, M. Kiehntopf, C. Hartog, C. Natanson, M. Loeffler, K. Reinhart   +22 more
semanticscholar   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

The Gut Microbiota-Insulin Resistance Axis: Mechanisms, Clinical Implications, and Therapeutic Potential. [PDF]

FASEB Bioadv
Al Qassab M, Chaarani N, Hamou A, Harb R, Jradi A, Zeineddine M, Ghadieh HE, Khattar ZA, Azar S, Kanaan A, Harb F.   +10 more
europepmc   +1 more source

Role of Insulin-Like Growth Factor Binding Protein-2 and Its Limited Proteolysis in Neuroblastoma Cell Proliferation: Modulation by Transforming Growth Factor-  and Retinoic Acid [PDF]

, 1997
M. Menouny
openalex   +1 more source

Identification of PKN2 and MOB4 as Coordinators of Collective Cell Migration

Advanced Science, EarlyView.
Through a genetic screen, PKN2 and MOB4 are identified as two proteins regulating the healing of an epithelial model wound. PKN2 promotes collective cell migration by maintaining the cohesion of cell monolayers from their lateral junctions, whereas MOB4 restrains collective cell migration and provides a lamellipodial cue for front‐rear polarity in ...
Artem I. Fokin, Yueying Lin, Dmitry Y. Guschin, Hsiang‐Ying Chen, John James, Jie Yan, Pascal Silberzan, Alexis M. Gautreau   +7 more
wiley   +1 more source