Results 191 to 200 of about 2,129,772 (314)

Harnessing Advances in Bone Tissue Engineering for Design of Bone‐on‐Chip Systems

Advanced Healthcare Materials, EarlyView.
Bone‐on‐chip (BoC) systems demonstrate significant potential as next‐generation models to study human (patho)physiology and evaluate new therapies. However, progress toward functional, human‐like BoCs has been hindered by the structural and functional complexity of bone. This perspective discusses how insights from bone tissue engineering can guide BoC
Farhad Sanaei, Yannick Hajee, Gerry L. Koons, David T. Wu, Sander C.G. Leeuwenburgh, Jeroen J.J.P. van den Beucken, Mani Diba   +6 more
wiley   +1 more source

Insulin resistance spawns hypertriglyceridemia-induced acute pancreatitis and diabetic ketoacidosis: an evolving metabolic cascade. [PDF]

Cardiovasc Endocrinol Metab
Wu C, Tiwari A, Zlatopolsky M, Qaqish O, Harder WE, Blaceri S, Saad C, Kambhatla S, Kondur A.   +8 more
europepmc   +1 more source

The paradox of fatty-acid β-oxidation in muscle insulin resistance: Metabolic control and muscle heterogeneity

Marcel A. Vieira‐Lara, Barbara M. Bakker   +1 more
openalex   +1 more source

Association of metabolic score for insulin resistance with gestational diabetes mellitus: a multicenter cohort study [PDF]

Qiong Li, Ailing Chen, Chenyang Zhao, Ying Zhang, Meng Li, Ying Gu, Yajing Pang, Yu Ping, Chaoyan Yue   +8 more
openalex   +1 more source

Identification of an obesity quantitative trait locus on mouse chromosome 2 and evidence of linkage to body fat and insulin on the human homologous region 20q. [PDF]

, 1997
A. V. Lembertas, Louis Përusse, Y. C. Chagnon, Janis S. Fisler, Craig H. Warden, D A Purcell-Huynh, France T. Dionne, Jean Gagnon, André Nadeau, Aldons J. Lusis, Claude Bouchard   +10 more
openalex   +1 more source

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Towards insulin independence in type 1 diabetes: Prospects for prevention and cure. [PDF]

PLoS Med
Sydney GI, Perdigoto AL, Herold KC.
europepmc   +1 more source

Natural Sweetener Stevioside‐Based Dissolving Microneedles Solubilize Minoxidil for the Treatment of Androgenic Alopecia

Advanced Healthcare Materials, EarlyView.
This study addresses limitations of minoxidil (MXD) in treating androgenetic alopecia by using stevioside (STV) as a solubilizing agent and microneedle (MN) material. STV enhanced MXD's solubility and skin absorption, leading to improved drug delivery and significant hair regrowth in animal models, demonstrating strong potential for AGA treatment ...
Junying Zhang, Tianyu Shao, Hailiang Li, Luying Zhu, Lamyaa Albakr, Nial J. Wheate, Lifeng Kang, Chungyong Wu   +7 more
wiley   +1 more source

Comparative Evaluation of Responsiveness of Insulin Counter-Regulatory Hormones and Insulin Resistance to Hypoglycemia in Newly Diagnosed Type 1 Diabetes Mellitus Man. [PDF]

Diabetes Metab Syndr Obes
Zhou Y, Zhou J, Ma J, Yan R, Yuan L, Huang R, Shen Y, Ding B.   +7 more
europepmc   +1 more source

Hypoglycemia Beliefs, Impaired Hypoglycemia Awareness, and Severe Hypoglycemia in Insulin-Treated Type 2 Diabetes: Insights From CGM Users [PDF]

Yu Kuei Lin, Haoran Tang, Wen Ye, Alexandria Ratzki‐Leewing, Joyce M. Lee, Nicole de Zoysa, Stephanie A. Amiel, William H. Herman   +7 more
openalex   +1 more source