Comparative analysis of fetomaternal outcome in women with gestational diabetes mellitus managed on different modalities [PDF]
Objectives: To compare fetomaternal outcome in women of gestational diabetes mellitus (GDM) managed on different modalities. Methods: A retrospective observational study was conducted in department of obstetrics and gynaecology at Vardhman Mahavir ...
Sumedha Gupta+4 more
doaj +1 more source
Biosimilar Insulin and Insulin Antibodies [PDF]
The introduction of biosimilar insulins in regulated markets is anticipated to happen in the next few years.1,2 However, biosimilar insulins are already on the market in a number of countries with little or no guidelines for approval of biosimilars and where approval is relatively easy to obtain.
David R. Owens, Lutz Heinemann
openaire +2 more sources
A proanthocyanidin from cinnamomum zeylanicum stimulates phosphorylation of insulin receptor in 3t3-l1 adipocytes [PDF]
Non-insulin-dependent diabetes mellitus is due to in large part to insulin resistance, a state where the target cells are no longer responding to ordinary levels of circulating insulin.
Abdul Majid, Fadzilah Adibah+2 more
core +1 more source
Hyperosmolar hyperglycemic state as the first manifestation of type 1 diabetes mellitus in an adolescent male: a case report [PDF]
A hyperosmolar hyperglycemic state (HHS) is a life-threatening complication rarely seen in children and adolescents with type 1 diabetes mellitus (T1DM).
Sang Hoon Chun+2 more
doaj +1 more source
The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver [PDF]
Secreted frizzled-related protein (sFRP) 4 is an adipokine with increased expression in white adipose tissue from obese subjects with type 2 diabetes and non-alcoholic fatty liver disease (NAFLD).
Al-Hasani, Hadi+12 more
core +1 more source
The prevalence of the metabolic syndrome in Portugal: the PORMETS study
Background The PORMETS study was designed to estimate the prevalence of metabolic syndrome and its determinants in the overall and administrative regions of the Portuguese mainland.
Luís Raposo+3 more
doaj +1 more source
Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. [PDF]
Defective hepatic insulin receptor (IR) signalling is a pathogenic manifestation of metabolic disorders including obesity and diabetes. The endo/lysosomal trafficking system may coordinate insulin action and nutrient homeostasis by endocytosis of IR and ...
Burnol, Anne-Françoise+7 more
core +1 more source
European lipodystrophy registry: background and structure
Background Lipodystrophy syndromes comprise a group of extremely rare and heterogeneous diseases characterized by a selective loss of adipose tissue in the absence of nutritional deprivation or catabolic state. Because of the rarity of each lipodystrophy
Julia von Schnurbein+24 more
doaj +1 more source
Effect of knocking down the insulin receptor on mouse rod responses. [PDF]
Previous experiments have shown that the insulin receptor (IR) is expressed in mammalian rods and contributes to the protection of photoreceptors during bright-light exposure.
Fain, Gordon L+3 more
core +3 more sources