Results 41 to 50 of about 1,441,623 (217)

The Relationship Between Insulin Resistance Neutrophil to Lymphocyte Ratio [PDF]

open access: yesarXiv, 2022
Aim: There is increasing interest in the role of chronic inflammation on pathogenesis of various disease, and one of its markers, high NLR is associated with various mortality and morbidity risk. Insulin resistance (IR) might be one potential associate factors, as suggested in preclinical studies.
arxiv  

Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability

open access: yesJournal of Diabetes Research, 2018
Variability in the effect of subcutaneously administered insulin represents a major challenge in insulin therapy where precise dosing is required in order to achieve targeted glucose levels.
A. K. J. Gradel   +6 more
doaj   +1 more source

Mouse Spexin: (III) Differential Regulation by Glucose and Insulin in Glandular Stomach and Functional Implication in Feeding Control

open access: yesFrontiers in Endocrinology, 2021
Spexin (SPX), a neuropeptide with diverse functions, is a novel satiety factor in fish models and its role in feeding control has been recently confirmed in mammals.
Yuan Chen   +7 more
doaj   +1 more source

Intermittent Control for Safe Long-Acting Insulin Intensification for Type 2 Diabetes: In-Silico Experiment [PDF]

open access: yesarXiv, 2023
Around a third of type 2 diabetes patients (T2D) are escalated to basal insulin injections. Basal insulin dose is titrated to achieve a tight glycemic target without undue hypoglycemic risk. In the standard of care (SoC), titration is based on intermittent fasting blood glucose (FBG) measurements.
arxiv  

Umbilical Cord Blood Leptin and IL-6 in the Presence of Maternal Diabetes or Chorioamnionitis

open access: yesFrontiers in Endocrinology, 2022
Diabetes during pregnancy is associated with elevated maternal insulin, leptin and IL-6. Within the placenta, IL-6 can further stimulate leptin production. Despite structural similarities and shared roles in inflammation, leptin and IL-6 have contrasting
Lauren K. Vasilakos   +6 more
doaj   +1 more source

Insulin Signaling and Insulin Resistance [PDF]

open access: yesJournal of Investigative Medicine, 2013
Insulin resistance or its sequelae may be the common etiology of maladies associated with metabolic syndrome (eg, hypertension, type 2 diabetes, atherosclerosis, heart attack, stroke, and kidney failure). It is thus important to understand those factors that affect insulin sensitivity.
openaire   +3 more sources

Golgi-associated retrograde protein (GARP) complex-dependent endosomes to trans Golgi network retrograde trafficking is controlled by Rab4b

open access: yesCellular & Molecular Biology Letters
Background The trafficking of cargoes from endosomes to the trans-Golgi network requires numerous sequential and coordinated steps. Cargoes are sorted into endosomal-derived carriers that are transported, tethered, and fused to the trans-Golgi network ...
Jérôme Gilleron   +4 more
doaj   +1 more source

Cinnamic Acid Derivatives as Antidiabetics Agents

open access: yesIndonesian Journal of Chemistry, 2017
Diabetes mellitus is a metabolic disorder of carbohydrate metabolism. Treatment of type II diabetes is usually done by prescribing diet and exercise for the patient however it can also be treated with antidiabetic drugs.
Teni Ernawati   +4 more
doaj   +1 more source

Insulin resistance and the polycystic ovary syndrome: mechanism and implications for pathogenesis.

open access: yesEndocrine reviews, 1997
It is now clear that PCOS is often associated with profound insulin resistance as well as with defects in insulin secretion. These abnormalities, together with obesity, explain the substantially increased prevalence of glucose intolerance in PCOS ...
A. Dunaif
semanticscholar   +1 more source

A Multicenter Survey of Type I Diabetes Mellitus in Chinese Children

open access: yesFrontiers in Endocrinology, 2021
PurposeTo investigate the features and treatment status of children with type 1 diabetes mellitus (T1DM) in China.MethodsWe recruited patients <14 years of age with T1DM from 33 medical centers in 25 major cities of China between January 2012 and ...
Ling Hou   +34 more
doaj   +1 more source

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