Results 81 to 90 of about 584,894 (281)

A case report and systematic literature review: insulin-induced type III hypersensitivity reaction

Frontiers in Allergy
Insulin-induced type III hypersensitivity reactions (HSRs) are exceedingly rare and pose complex diagnostic and management challenges. We describe a case of a 43-year-old woman with type 1 diabetes mellitus (DM), severe insulin resistance, and ...
Rebecca R. Meredith, Pooja Patel, Polly Huang, Chinelo Pamela Onyenekwu, Herleen Rai, Jody Tversky, Santiago Alvarez-Arango, Santiago Alvarez-Arango   +7 more
doaj   +1 more source

Type 1 Ig-E mediated allergy to human insulin, insulin analogues and beta-lactam antibiotics Hipersensibilidade imediata a insulina humana, análogos de insulina e a antibióticos beta-lactâmicos

Anais Brasileiros de Dermatologia, 2012
Insulin, a crucial therapeutic agent for diabetes mellitus, has been rarely associated with hypersensitivity events. We present a 69-year-old type-2 diabetic patient with urticariform lesions on the sites of subcutaneous injection of insulin. The patient
Pedro Andrade, Luísa Barros, Margarida Gonçalo   +2 more
doaj   +1 more source

Amino Acid and Biogenic Amine Profiles in Sausages Reformulated With Processed, Fermented Oyster Mushrooms

ChemFoodChem, EarlyView.
This research showed that sausage reformulation preserves high essential amino acid and branched‐chain amino acid content, as well as increasing free amino acids (FAA) related to umami flavor and health‐promoting components such as GABA in the products.
Albert Gashi, György Kenesei, Meltem Boylu Kovács, Zsuzsanna Mednyánszky, Livia Simon Sarkadi   +4 more
wiley   +1 more source

Antimicrobial Peptides and Peptidomimetics in Foods – A Synthetic Foray

ChemFoodChem, EarlyView.
This Review discusses AMPs in foods and their syntheses. It espouses facile methods to make them accessible and suggests their utility in the mitigation and eradication of the burgeoning maladies of antimicrobial and multidrug resistance (AMR and MDR).
Josephat U. Izunobi, Adejoke D. Osinubi, Abosede A. Badeji   +2 more
wiley   +1 more source

Chitinase 3-Like 1 Contributes to Food Allergy via M2 Macrophage Polarization [PDF]

, 2020
Purpose: Food allergy is a hypersensitive immune response to specific food proteins. Chitinase 3-like 1 (CHI3L1, also known as YKL-40 in humans or BRP-39 in mice) is associated with various chronic diseases, such as cancer, rheumatoid arthritis, and ...
김경원, 손명현, 김미나, 홍정연, 김수연, Chun Geun Lee, Kyung Won Kim, Jack A. Elias, Soo Yeon Kim, Eun Gyul Kim, Jung Yeon Hong, Tae Won Song, Myung Hyun Sohn, Jae Woo Lee, Mi Na Kim   +14 more
core   +1 more source

Enhancing Evidence Generation by Linking Randomized Clinical Trials to Real‐World Data: The INVESTED‐Medicare Linkage Study

Clinical Pharmacology &Therapeutics, EarlyView.
Real‐world evidence (RWE) derived from real‐world data (RWD) can complement randomized controlled trials (RCTs), yet the validity of RWD relative to RCT data remains insufficiently characterized. We obtained post hoc consent and linked individual participant data from the US‐based INVESTED trial (2016–2019) with Medicare fee‐for‐service claims (2012 ...
Hanseul Cho, HoJin Shin, Mehdi Najafzadeh, Brian Claggett, Janinne Ortega‐Montiel, Jun Liu, Julie M. Paik, Narlina F. Lalani, Marie C. Bradley, John Concato, Scott D. Solomon, Orly Vardeny, Elisabetta Patorno   +12 more
wiley   +1 more source

Successful Modified Desensitization Therapy with Analog Insulin in an Individual with Severe Allergy to Multiple Insulin Preparations: A Case Report

Journal of the ASEAN Federation of Endocrine Societies, 2018
We present a case of a 27-year-old lady with T2 DM who developed allergic reactions after commencement of insulin therapy. Trial with different types of insulin resulted in a series of allergic reactions ranging from urticarial rash to development of ...
Wan Juani Wan Seman, Azraai Bahari Nasruddin, Nurain Mohd Noor   +2 more
doaj  

Human insulin allergy: four case reports

, 2010
International audienceInsulin allergy was not uncommon in the past, but has lowered with the introduction of human recombinant insulin. Human recombinant insulin allergy is a rare condition, now reported in less than 1% of treated patients.
Sabino Garro, L, Kase Tanno, Luciana, Ensina, Luis, Teixeira Rodrigues, A, Motta, Antonio Abilio, Giavina-Bianchi, Pedro   +5 more
core  

Developments in the field of allergy in 2017 through the eyes of Clinical and Experimental Allergy [PDF]

, 2018
In this article, we described the development in the field of allergy as described by Clinical and Experimental Allergy in 2017. Experimental models of allergic disease, basic mechanisms, clinical mechanisms, allergens, asthma and rhinitis and clinical ...
Hogan, S. P., Crane, J., Saglani, S., Roberts, G., Woodfolk, J. A., Almqvist, C., Boyle, R., Marsland, B., Boyle, R, Almqvist, C, Saglani, S, Woodfolk, JA, Marsland, B, Hogan, SP, Roberts, G, Crane, J   +15 more
core   +1 more source

Considerations for the Integration of Clinical Trials and Real‐World Data

Clinical Pharmacology &Therapeutics, EarlyView.
As clinical decision‐making increasingly moves toward individualized and context‐specific treatment recommendations, reliance on any single evidence source, randomized or observational, may be insufficient. Principled integration of randomized controlled trials and real‐world data, grounded in explicit causal frameworks, offers a path toward evidence ...
Sky Qiu, Charles E. Barr, Lauren Dang, Larry Han, Kajsa Kvist, Hana Lee, Andrew Mertens, Nerissa Nance, Lei Nie, Kara Rudolph, Xu Shi, Jens Tarp, Salina P. Waddy, Kenneth Wiley, Andy Wilson, Margot Lisa Jing Yann, Zhiwei Zhang, Tianyue Zhou, Maya Petersen, Mark van der Laan   +19 more
wiley   +1 more source