Results 101 to 110 of about 269,490 (301)

A case of type B insulin resistance syndrome treated with low-dose glucocorticoids

Endocrinology, Diabetes & Metabolism Case Reports, 2019
Type B insulin resistance syndrome is characterized by the presence of autoantibodies to the insulin receptor. We present a 57-year-old male admitted to a hospital due to body weight loss of 16 kg and hyperglycemia of 13.6 mmol/L.
Masato Kotani, Naohisa Tamura, Tatsuhide Inoue, Issei Tanaka   +3 more
doaj   +1 more source

In vivo relationship between bound and free insulin in patients with diabetes having anti-insulin antibodies. [PDF]

Diabetol Int, 2023
Asaka H, Karashima S, Chujo D, Kometani M, Usukura M, Yagi K, Aiga K, Yoneda T.   +7 more
europepmc   +1 more source

Anti-Insulin Receptor Antibodies Improve Hyperglycemia in a Mouse Model of Human Insulin Receptoropathy.

, 2020
Loss-of-function mutations in both alleles of the human insulin receptor gene (INSR) cause extreme insulin resistance (IR) and usually death in childhood, with few effective therapeutic options.
Brierley, Gemma V., Grocott, Sarah, Siddle, Kenneth, Webber, Hannah, Rasijeff, Eerika, Semple, Robert K; id_orcid   +5 more
core   +1 more source

Extracellular Vesicles Modulation by an Adiponectin Receptor Agonist Provides Cardioprotection for Myocardial Ischemic Injury

Advanced Healthcare Materials, EarlyView.
This study demonstrates that ALY688, a drug mimicking the heart‐protective hormone adiponectin, reduces myocardial ischemia injury. ALY688 increases the production of extracellular vesicles, which carry protective cargo including adiponectin itself.
Jialing Tang, Wing Yan Chung, Serena M. Pulente, Yubin Lei, Khang Nguyen, Eddie Tam, Nadya M. Morrow, Ilka Lorenzen‐Schmidt, Fengxia Xiao, Augusto Zani, Dylan Burger, Hye Kyoung Sung, Erin E. Mulvihill, Gary Sweeney   +13 more
wiley   +1 more source

Anti-insulin antibodies in diabetic dogs before and after treatment with different insulin preparations.

, 2008
BACKGROUND: Anti-insulin antibodies (AIA) occur in diabetic dogs after insulin therapy, although their clinical significance is unclear. HYPOTHESIS: Treatment of diabetic dogs with heterologous insulin is more likely to stimulate production of AIA than ...
Herrtage, M E, B. Catchpole, Walding, B, Walding, B R, M.E. Herrtage, Davison, LJ, L.J. Davison, Catchpole, B, B. Walding, Cambridge, Herrtage, ME, Davison, L J   +11 more
core   +1 more source

Identification and characterization of insulin-like growth factor receptors on adult rat cardiac myocytes: linkage to inositol 1,4,5-trisphosphate formation. [PDF]

, 1992
Cultured cardiac myocytes from adult Sprague-Dawley rats express both insulin-like growth factor-I (IGF-I) receptors and insulin-like growth factor-II/mannose 6-phosphate (IGF-II/Man6P) receptors and respond to IGF-I with a dose-dependent accumulation of
Berg, Ingeborg, Guse, Andreas H., Kessler, Ulrike, Funk, Barbara, Gercken, Günther, A. H. Guse, Kiess, Wieland   +6 more
core   +1 more source

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

Prevalence of thyroid dysfunction in patients with Type 2 diabetes mellitus and its correlation with insulin resistance and serum markers for autoimmune thyroiditis

Asian Journal of Medical Sciences, 2015
Background: The term “THYROID DIABETES” was coined in early literature to depict the influence of thyroid hormone excess in deterioration of glucose control.
Sulagna Sahu
doaj   +1 more source

Insulinoma With Concomitant Insulin Antibodies. [PDF]

AACE Clin Case Rep, 2021
Iqbal A, Broome DT, Makin V, Yogi-Morren D.   +3 more
europepmc   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source