Results 141 to 150 of about 269,490 (301)

Specificities of rabbit anti-human insulin receptor antibodies

open access: yes, 1979
Human insulin receptors obtained from normal human placentae were highly purified by affinity chromatography and used to immunize rabbits. The immunological response was evaluated in order to reveal the presence of antibodies blocking the binding of ...
Musiani, P.   +7 more
core  

Electroacupuncture Improves the Learning and Memory by Modulating Hippocampal Glucose Metabolism through IGF1/IGF1R Signaling in Alzheimer's Disease

open access: yesAdvanced Science, EarlyView.
Electroacupuncture (EA) ameliorates learning and memory function in 5×FAD mice by regulating the brain glucose metabolic network. This neuroprotective effect is closely related to enhancing neuronal energy utilization via the IGF1/IGF1R signaling pathway.
Shengxiang Liang   +12 more
wiley   +1 more source

Antibodies and distortion of insulin and C-peptide results in patients with hypoglycaemia of unknown origin

open access: yesClinical Medicine
Two types of antibody could confuse the differential diagnosis of hypoglycaemia. One is insulin-binding autoantibodies (IAA), a double hit causing hypoglycaemia of insulin autoimmune syndrome (IAS, also known as Hirata’s disease) as well as distorting ...
Adel A.A. Ismail
doaj   +1 more source

[Preparation of 125I-labelled monoclonal antibodies of the insulin receptor]

open access: yes, 1988
Three monoclonal anti-insulin receptor antibodies have been labelled with 125I according to various methods (Cloramine T, Lactoperoxidase and IODO-GEN). The effect of labelling on antibody structure and function has been characterized using the following
Monaco, F   +15 more
core  

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

Insulin-, glucagon- and somatostatin-positive cells in pancreatic islets during aging in C57BL/6 mice.

open access: yes, 2016
(A) Beta cells in pancreatic islets from different ages (4, 8, 12, and 20 months) of mice were examined by immunohistochemical staining with an antibody against insulin. Representative images are shown at × 200 magnification.
Yoon Sin Oh (345480)   +6 more
core   +1 more source

A 3D In Vitro Model of the Human Hepatobiliary Junction

open access: yesAdvanced Science, EarlyView.
A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield   +13 more
wiley   +1 more source

Exogenous Insulin Antibody Syndrome: An Overlooked Cause of Severe Hypoglycemia and Insulin Resistance in a Patient With Type 2 Diabetes Treated With Insulin

open access: yesJournal of General and Family Medicine
We report an 80‐year‐old man with type 2 diabetes who presented with life‐threatening hypoglycemia (36 mg/dL) and coma, requiring high‐dose insulin (74 units/day).
Kazuki Miyaue, Hiroki Isono
doaj   +1 more source

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