Results 61 to 70 of about 269,490 (301)

Epidemiology and immunogenetic background of islet cell antibody - positive nondiabetic schoolchildren : Ulm-Frankfurt population study [PDF]

, 1991
Islet cell antibodies (ICAs) were determined in a large cohort of white nondiabetic schoolchildren (n = 4287) from a homogenous population in southern Germany.
Glück, Michael, Schöffling, Karl, Trucco, Massimo, Seißler, Jochen, Böhm, Bernhard Otto, Holzberger, G., Scherbaum, Werner A., Seidl, S., Manfras, Burkhard J., Kühnl, Peter   +9 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

REAGIN-SPECIFIC RESPONSE TO INSULIN LEVEL IN CARBOHYDRATE METABOLISM DISORDERS IS DEPENDENT ON THE BLOOD GROUP ABO ANTIGENIC DETERMINANTS

Медицинская иммунология, 2018
The paper presents evidence that the individuals with different blood groups and glucose levels exhibit individual IgE reagin responses to insulin. Thus, the persons with 0 (I) blood group showed the highest values of anti-insulin-specific IgE (124.83±67.
N. R. Telesmanich, M. A. Konovalchik, Z. I. Mikashinovich, E. G. Krivolapova   +3 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Clinical Studies on Insulin Antibodies Part II. Significance of Insulin Antibodies as Determinants of Diabetic Control in Insulin Treated Diabetics [PDF]

, 1981
The significance of insulin antibodies in determining diabetic control was examined in 56 patients treated with insulin. Diurnal changes in blood glucose, serum free insulin and bound insulin concentrations were measured.
Yagyu, Fumito
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Clinical Studies on Insulin Antibodies Part I. A New Method for Quantitative Determination of Insulin Antibodies [PDF]

, 1981
A new method is described for quantitative determination of insulin antibodies. In this method, the insulin binding, capacity of non-iodinated insulin is determined. Diluted serum containing insulin antibodies was saturated by native insulin.
Yagyu, Fumito
core  

Zinc transporter 8 antibodies complement GAD and IA-2 antibodies in the identification and characterization of adult-onset autoimmune diabetes: Non Insulin Requiring Autoimmune Diabetes (NIRAD) 4.

, 2009
OBJECTIVE: Zinc transporter 8 (ZnT8) is an islet beta-cell secretory granule membrane protein recently identified as an autoantibody antigen in type 1 diabetes.
S. Bonicchio, Emanuele Bosi, Sara Bonicchio, Songini M, Lampasona V, Sergio di Pietro, SPOLETINI, MARIA LUISA, Non Insulin Requiring Autoimmune Diabetes Study Group, GIORGINO, Francesco, F. Giorgino, Bonicchio S, Vito Lampasona, CAPIZZI, MARCO, Marco Songini, S. Di Pietro, E. Bosi, Francesco Giorgino, TIBERTI, Claudio, Marialuisa Spoletini, Bosi E, Bonifacio E, For The Nirad Study Group, Spoletini M, Antonio Petrone, Raffaella Buzzetti, Buzzetti R, M. Songini, Capizzi M, Petrone A, Marco Capizzi, di Pietro S, Ezio Bonifacio, V. Lampasona, Tiberti C, PETRONE, ANTONIO, E. Bonifacio, BUZZETTI, Raffaella, Claudio Tiberti   +37 more
core   +1 more source

Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland [PDF]

, 2005
We have demonstrated that insulin-like growth factor binding protein-5 (IGFBP-5) production by mammary epithelial cells increases dramatically during forced involution of the mammary gland in rats, mice and pigs.
Beattie, J, Whitelaw C. B. A., ACCORSI, PIER ATTILIO, Hurley, W, Boutinaud, M, Kolb A., Allan G. A., Tonner, E, Wilde, C J, Boutinaud M., Wilde C. J., Beattie J., Accorsi, P A, Flint, D J, Flint D. J., Tonner E., Whitelaw, C B A, Hurley W., Kolb, A F, Allan, G J   +19 more
core   +1 more source