Results 11 to 20 of about 115,305 (240)
Insulin dysregulation in horses with systemic inflammatory response syndrome. [PDF]
BackgroundSystemic inflammation is a cause of insulin dysregulation in many species, but the insulin and glucose dynamics in adult horses diagnosed with systemic inflammatory response syndrome (SIRS) are poorly documented.Hypothesis/ObjectivesIn SIRS in horses, insulin and glucose dynamics will be altered and associated with survival.AnimalsAdult ...
Bertin FR, Ruffin-Taylor D, Stewart AJ.
europepmc +5 more sources
Effects of the Sodium‐Glucose Cotransporter‐2 Inhibitor Velagliflozin on Insulin Concentrations in Horses With Insulin Dysregulation [PDF]
Background Sodium‐glucose cotransporter‐2 inhibitors (SGLT2i) are promising treatments to manage hyperinsulinemia in horses with insulin dysregulation (ID). Hypothesis The SGLT2i velagliflozin decreases insulin concentration in horses with ID.
Kristen Thane +5 more
doaj +2 more sources
Blood Glucose and Insulin Concentrations after Octreotide Administration in Horses With Insulin Dysregulation. [PDF]
BackgroundOctreotide is a somatostatin analog that suppresses insulin secretion.HypothesisWe hypothesized that octreotide would suppress insulin concentrations in horses and that normal (N) horses and those with insulin dysregulation (ID) would differ significantly in their plasma glucose and insulin responses to administration of octreotide ...
Frank N +5 more
europepmc +3 more sources
Obesity has become a serious health problem with frequent occurrence both in human and animal populations. It is estimated that it may affect over 85% of the human population and 70–80% of horses and cows by 2030.
Zsofia Daradics +7 more
doaj +1 more source
BackgroundThe prevalence of Equine Metabolic Syndrome and insulin dysregulation is increasing in the horse population. Insulin dysregulation is a risk factor for laminitis, which has significant welfare consequences for the horse.
Alexandra von Münchow +6 more
doaj +1 more source
Although there are many hormonal changes associated with reproduction, the effects of ovulation and early pregnancy on adrenocorticotropic hormone (ACTH) and insulin concentrations are poorly described.
Gemma R. Hicks +2 more
doaj +1 more source
Background Sphingolipids modulate insulin sensitivity in mammals. Increased synthesis of ceramides is linked to decreased insulin sensitivity of tissues.
Yue Hei Leung +4 more
doaj +1 more source
BackgroundIn focal congenital hyperinsulinism (CHI), surgery is the gold standard of treatment, even for lesions localized in the head of the pancreas.
Gionata Spagnoletti +7 more
doaj +1 more source
The diagnosis of equine insulin dysregulation [PDF]
Summary Insulin dysregulation is the hallmark of equine metabolic syndrome and has received attention because of its direct association with laminitis. In the absence of an adequate treatment for laminitis, a focus on prophylaxis is needed, making early detection of individuals at risk of developing laminitis one of the main ...
F. R. Bertin, M. A. de Laat
openaire +3 more sources
Effect of sirolimus on insulin dynamics in horses
Background Sirolimus, a mechanistic target of rapamycin inhibitor, suppresses insulin production in other species and has therapeutic potential for hyperinsulinemia in horses.
Demia J. deTonnerre +6 more
doaj +1 more source

