Results 31 to 40 of about 134,602 (231)

Infection and Immunometabolism in the Central Nervous System: A Possible Mechanistic Link Between Metabolic Imbalance and Dementia

Frontiers in Cellular Neuroscience, 2021
Metabolic syndromes are frequently associated with dementia, suggesting that the dysregulation of energy metabolism can increase the risk of neurodegeneration and cognitive impairment.
Noriko Shinjyo, Noriko Shinjyo, Kiyoshi Kita, Kiyoshi Kita   +3 more
doaj   +1 more source

Haptoglobin, Magnesium, Adiponectin, and Leptin as Biomarkers for Obesity and Insulin Dysregulation in Horses

International Journal of Equine Science, 2022
The aim of this project was to identify blood analytes which are associated with obesity and/or insulin dysregulation (ID) in horses. For this study, 57 horses were selected.
Guillaume Counotte, Andy Durham, Veerle Vandendriessche, Linda Wollenberg, van den   +3 more
doaj  

THE METABOLIC-MICROVASCULAR DYSREGULATION SYNDROME

Artery Research, 2017
Microvascular and metabolic physiology are inextricably linked. Thus, metabolic dysfunction impairs microvascular function and microvascular dysfunction impairs normal metabolism.
Coen D.A. Stehouwer
doaj   +1 more source

Comparison of Feed Digestibility between Ponies, Standardbreds and Andalusian Horses Fed Three Different Diets

Veterinary Sciences, 2021
Ponies and some horse breeds such as Andalusians exhibit an ‘easy keeper’ phenotype and tend to become obese more readily than other breeds such as Standardbreds.
Samantha J. Potter, Nicholas J. Bamford, Courtnay L. Baskerville, Patricia A. Harris, Simon R. Bailey   +4 more
doaj   +1 more source

Regulation of cardiac expression of the diabetic marker microRNA miR-29.

PLoS ONE, 2014
Diabetes mellitus (DM) is an independent risk factor for heart disease and its underlying mechanisms are unclear. Increased expression of diabetic marker miR-29 family miRNAs (miR-29a, b and c) that suppress the pro-survival protein Myeloid Cell Leukemia
Nicholas Arnold, Purushotham Reddy Koppula, Rukhsana Gul, Christian Luck, Lakshmi Pulakat   +4 more
doaj   +1 more source

The sodium-glucose co-transporter 2 inhibitor velagliflozin reduces hyperinsulinemia and prevents laminitis in insulin-dysregulated ponies. [PDF]

PLoS ONE, 2018
There are no registered veterinary drugs for treating insulin dysregulation and preventing insulin-associated laminitis in horses. Velagliflozin is a sodium-glucose co-transport 2 inhibitor that reduces renal glucose reabsorption, promotes glucosuria ...
Alexandra Meier, Dania Reiche, Melody de Laat, Christopher Pollitt, Donald Walsh, Martin Sillence   +5 more
doaj   +1 more source

Development of a Web App to Convert Blood Insulin Concentrations among Various Immunoassays Used in Horses

Animals, 2023
The measurement of the blood insulin concentration, and comparison to cut-offs, is essential in diagnosing insulin dysregulation, a common equine endocrinopathy. However, different insulin assays provide disparate results.
Julien Delarocque, Karsten Feige, Harry B. Carslake, Andy E. Durham, Kerstin Fey, Tobias Warnken   +5 more
doaj   +1 more source

Erratum for "Effect of phenylbutazone on insulin secretion in horses with insulin dysregulation". [PDF]

J Vet Intern Med
europepmc   +2 more sources

An Anti-Inflammatory Sterol Decreases Obesity-Related Inflammation-Induced Insulin Resistance and Metabolic Dysregulation

Mediators of Inflammation, 2013
Obesity-related inflammation-induced insulin resistance and metabolic dysregulation were investigated in retrospective analysis of placebo hematologic and metabolic laboratory data from trials associated with increasing chronic low-grade inflammation and
Chris L. Reading, Jaime Flores-Riveros, Dwight R. Stickney, James M. Frincke   +3 more
doaj   +1 more source

Role of Protein Kinase C in Insulin Resistance and Metabolic Syndrome

Kinases and Phosphatases
One mechanism contributing to insulin resistance is the serine/threonine phosphorylation of critical proteins involved in insulin signaling, particularly the insulin receptor, its downstream substrates, and the activation of protein tyrosine phosphatases.
Daphne E. Cruz-Villarreal, Karla D. Hernandez-Gonzalez, J. Alberto Olivares-Reyes   +2 more
doaj   +1 more source