Results 11 to 20 of about 134,602 (231)

Insulin dysregulation in horses with induced obesity [PDF]

Pesquisa Veterinária Brasileira, 2020
: Insulin deregulation (ID) is a central player in the pathophysiology of equine metabolic syndrome (EMS), which is associated with generalized and/or regional obesity.
Rodrigo M. Ribeiro, Debora S.F. Ribeiro, Cahuê Francisco R. Paz, Alexandre A.O. Gobesso, Rafael R. Faleiros   +4 more
doaj   +5 more sources

Obesity-Related Metabolic Dysfunction in Dairy Cows and Horses: Comparison to Human Metabolic Syndrome

Life, 2021
Obesity has become a serious health problem with frequent occurrence both in human and animal populations. It is estimated that it may affect over 85% of the human population and 70–80% of horses and cows by 2030.
Zsofia Daradics, Cristian M. Crecan, Mirela A. Rus, Iancu A. Morar, Mircea V. Mircean, Adriana Florinela Cătoi, Andra Diana Cecan, Cornel Cătoi   +7 more
doaj   +1 more source

Oligosaccharide feed supplementation reduces plasma insulin in geldings with Equine Metabolic Syndrome

Frontiers in Microbiomes, 2023
BackgroundThe prevalence of Equine Metabolic Syndrome and insulin dysregulation is increasing in the horse population. Insulin dysregulation is a risk factor for laminitis, which has significant welfare consequences for the horse.
Alexandra von Münchow, Alexandra von Münchow, Sarah Torp Yttergren, Rasmus Riemer Jakobsen, Nanna Luthersson, Axel Kornerup Hansen, Frederikke Lindenberg   +6 more
doaj   +1 more source

Effects of pasture consumption and obesity on insulin dysregulation and adiponectin concentrations in UK native-breed ponies [PDF]

Equine Veterinary Journal
Nicola Menzies-Gow, Jonathan Elliott, Marine A Barnabe   +2 more
exaly   +2 more sources

ATGL links insulin dysregulation to insulin resistance in adolescents with obesity and hepatosteatosis. [PDF]

J Clin Invest
BACKGROUND This study examined the underlying cellular mechanisms associated with insulin resistance (IR) and metabolic disease risk within subcutaneous adipose tissue (SAT) in youth with obesity and IR compared with those without IR. METHODS
Slusher AL, Santoro N, Vash-Margita A, Galderisi A, Hu P, Tokoglu F, Li Z, Tarabra E, Strober J, Vatner DF, Shulman GI, Caprio S.   +11 more
europepmc   +4 more sources

Changes Associated with the Peri-Ovulatory Period, Age and Pregnancy in ACTH, Cortisol, Glucose and Insulin Concentrations in Mares

Animals, 2021
Although there are many hormonal changes associated with reproduction, the effects of ovulation and early pregnancy on adrenocorticotropic hormone (ACTH) and insulin concentrations are poorly described.
Gemma R. Hicks, Natalie S. Fraser, François-René Bertin   +2 more
doaj   +1 more source

Associations of plasma sphingolipid profiles with insulin response during oral glucose testing in Icelandic horses

Journal of Veterinary Internal Medicine, 2021
Background Sphingolipids modulate insulin sensitivity in mammals. Increased synthesis of ceramides is linked to decreased insulin sensitivity of tissues.
Yue Hei Leung, Ákos Kenéz, Anne Julia Grob, Karsten Feige, Tobias Warnken   +4 more
doaj   +1 more source

Case report: Pylorus-preserving pancreatoduodenectomy for focal congenital hyperinsulinism in a 5-month-old baby

Frontiers in Surgery, 2023
BackgroundIn focal congenital hyperinsulinism (CHI), surgery is the gold standard of treatment, even for lesions localized in the head of the pancreas.
Gionata Spagnoletti, Zoe Larghi Laureiro, Alberto Maria Fratti, Arianna Maiorana, Maria Carmen Garganese, Milena Pizzoferro, Carlo Dionisi-Vici, Marco Spada   +7 more
doaj   +1 more source

Interplay Between Insulin Resistance and Immune Dysregulation in Type 2 Diabetes Mellitus: Implications for Therapeutic Interventions

ImmunoTargets and Therapy
Afiat Berbudi,1– 3 Shafia Khairani,4 Adi Imam Tjahjadi2,3,5 1Department of Biomedical Sciences, Parasitology Division, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; 2Research Center for Care and Control of Infectious Diseases (RC3ID),
Berbudi A, Khairani S, Tjahjadi AI
doaj   +2 more sources

Effect of sirolimus on insulin dynamics in horses

Journal of Veterinary Internal Medicine, 2023
Background Sirolimus, a mechanistic target of rapamycin inhibitor, suppresses insulin production in other species and has therapeutic potential for hyperinsulinemia in horses.
Demia J. deTonnerre, Carlos E. Medina Torres, Darko Stefanovski, Mary A. Robinson, Kate L. Kemp, François‐René Bertin, Andrew W. vanEps   +6 more
doaj   +1 more source