Results 221 to 230 of about 189,129 (283)

Inconsistent Transcriptomic Responses to Hexabromocyclododecane in Japanese Quail: A Comparative Analysis of Results From Four Different Study Designs

Environmental Toxicology and Chemistry, EarlyView.
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers, Elena Legrand, Emily Boulanger, Niladri Basu, Jessica D. Ewald, Paula Henry, Markus Hecker, Jianguo Xia, Natalie Karouna‐Renier, Doug Crump, Jessica Head   +10 more
wiley   +1 more source

Bioengineered Isoflavone–Probiotic Functional Foods for Sustainable Modulation of Metabolic and Reproductive Health in PCOS

Food Bioengineering, EarlyView.
Synergistic isoflavone‐probiotic action modulated metabolic, microbial and ovarian pathway ABSTRACT Polycystic ovary syndrome (PCOS) is a prevalent metabolic–endocrine disorder characterized by insulin resistance, hyperandrogenism, chronic inflammation, oxidative stress, and ovarian dysfunction, with growing evidence implicating gut microbiota ...
Jeyavelkumaran Renukadevi, Panneerselvam Sneha, Dhanapal Saravanan Mridula, Keerthivasan Nimithasree, Valliappan Sanjay   +4 more
wiley   +1 more source

A Nutritional Paradigm to Impede Cataract Initiation: A Narrative Review of Emerging Perspective on Nutraceuticals

Future Postharvest and Food, EarlyView.
By lowering oxidative stress and lens protein aggregation, nutraceuticals enriched with antioxidants may reduce the development of senile cataracts, demonstrating their potential as supplemental, non‐pharmacological cataract preventive methods. ABSTRACT This review explores the emerging evidence to accommodate the developing requirement of non ...
Moubani Dutta, Sankhajyoti Saha, Agnihiya Bosu   +2 more
wiley   +1 more source

Phytochemicals and Health Benefits of American Ginseng (Panax quinquefolius L.): Current Knowledge and Future Perspectives

Food Safety and Health, EarlyView.
This review summarizes the chemical constituents and functional characteristics of American ginseng, aiming to provide references for its development and application. ABSTRACT American ginseng, a perennial herbaceous plant, is recognized for its significant medicinal properties and has attracted considerable attention due to its diverse phytochemical ...
Wei Geng, Ning Zhou, Jinqian Yu, Yanling Geng, Xiao Wang, Yannan Chen   +5 more
wiley   +1 more source

Genetically reducing mTOR signaling rescues central insulin dysregulation in a mouse model of Alzheimer's disease.

Neurobiol Aging, 2018
Caccamo A, Belfiore R, Oddo S.
europepmc   +1 more source

The Depth‐Specific Effects of Acupuncture for Post‐Stroke Gastroparesis: Protocol for a Randomized Controlled Trial of Deep Versus Superficial Needling

Gut Medicine, EarlyView.
ABSTRACT Background Post‐stroke gastroparesis (GP) is a debilitating complication that severely impairs quality of life. Although abdominal acupuncture is widely used, robust evidence regarding its efficacy, particularly concerning the critical parameter of the needling depth, is still lacking.
Xiangcheng Wei, Can Wang, Yuan Qin, Lanping Li, Shiqing Zhao, Yee Hwee Cheong, Yang Guo, Lingyong Xiao, Xiaoyu Dai   +8 more
wiley   +1 more source

Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

Gut Medicine, EarlyView.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei, Xin‐Wei Sun, Hao‐Jie Huang, Yu‐Zhi Zhao, Shuang‐Jiang Liu, Chang Liu   +5 more
wiley   +1 more source

The effect of body mass index change on breast and uterine cancer risk in middle‐ and older‐aged adults

International Journal of Cancer, EarlyView.
What's New? While baseline body mass index (BMI) is known to affect cancer risk, the impact of BMI change over time remains unclear. This large cohort study evaluated the association between longitudinal BMI change and the risk of breast and uterine corpus cancers in Korean women, with stratification by menopausal and smoking status.
Su Youn Nam, Junwoo Jo
wiley   +1 more source

Role of Inflammatory Cytokines and Endocrine Dysregulation in Pain-Related Cardiovascular and Metabolic Dysfunction: A Narrative Review. [PDF]

Cureus
Azeez OM, Olaniyi H, Oyovwi JO, Oyovwi MI, Okafor CP, Folasole A, Okeoma OI, Olaniyi AO.   +7 more
europepmc   +1 more source

Long‐term association of physical activity with survival by primary cancer treatment in endometrial cancer: The Alberta Endometrial Cancer Cohort Study

International Journal of Cancer, EarlyView.
What's New? Accumulating evidence suggests a beneficial role of physical activity in cancer. However, it is unclear whether associations between physical activity and cancer outcomes vary by cancer treatment. Based on more than 16 years of follow‐up data from a cohort of endometrial cancer survivors, this study reveals that associations between ...
Minsuk Oh, Ki‐Yong An, Dong Hoon Lee, Renée L. Kokts‐Porietis, Linda S. Cook, Christine M. Friedenreich, Justin Y. Jeon, Kerry S. Courneya   +7 more
wiley   +1 more source