Results 31 to 40 of about 115,305 (240)

THE METABOLIC-MICROVASCULAR DYSREGULATION SYNDROME

Artery Research, 2017
Microvascular and metabolic physiology are inextricably linked. Thus, metabolic dysfunction impairs microvascular function and microvascular dysfunction impairs normal metabolism.
Coen D.A. Stehouwer
doaj   +1 more source

Clinical evaluation of the Immulite® 1000 chemiluminescent immunoassay for measurement of equine serum insulin

Frontiers in Veterinary Science, 2023
IntroductionAccurate quantitative analysis of equine insulin in blood samples is critical for assessing hyperinsulinemia in horses. Although there are various laboratory methods for evaluating equine serum insulin, different immunoassays show significant
Yun Young Go, Nicole W. Hazard, Udeni B. R. Balasuriya, Anna M. Chapman, Nanette S. Fitton, Ákos Kenéz, Frank M. Andrews   +6 more
doaj   +1 more source

Haptoglobin, Magnesium, Adiponectin, and Leptin as Biomarkers for Obesity and Insulin Dysregulation in Horses

International Journal of Equine Science, 2022
The aim of this project was to identify blood analytes which are associated with obesity and/or insulin dysregulation (ID) in horses. For this study, 57 horses were selected.
Guillaume Counotte, Andy Durham, Veerle Vandendriessche, Linda Wollenberg, van den   +3 more
doaj  

Multiple micronutrient deficiencies alter energy metabolism in host and gut microbiome in an early-life murine model

Frontiers in Nutrition, 2023
IntroductionMicronutrients perform a wide range of physiological functions essential for growth and development. However, most people still need to meet the estimated average requirement worldwide.
Paula T. Littlejohn, Paula T. Littlejohn, Haggai Bar-Yoseph, Karlie Edwards, Hong Li, Cynthia Y. Ramirez-Contreras, Ravi Holani, Avril Metcalfe-Roach, Avril Metcalfe-Roach, Yiyun M. Fan, Tom Min-Shih Yang, Nina Radisavljevic, Nina Radisavljevic, Xiaoke Hu, James D. Johnson, B. Brett Finlay, B. Brett Finlay, B. Brett Finlay   +17 more
doaj   +1 more source

Overfeeding Extends the Period of Annual Cyclicity but Increases the Risk of Early Embryonic Death in Shetland Pony Mares

Animals, 2021
Obesity has been associated with altered reproductive activity in mares, and may negatively affect fertility. To examine the influence of long-term high-energy (HE) feeding on fertility, Shetland pony mares were fed a diet containing 200% of net energy ...
Nicky M. M. D’Fonseca, Charlotte M. E. Gibson, Iris Hummel, David A. van Doorn, Ellen Roelfsema, Tom A. E. Stout, Jan van den Broek, Marta de Ruijter-Villani   +7 more
doaj   +1 more source

Regulation of cardiac expression of the diabetic marker microRNA miR-29.

PLoS ONE, 2014
Diabetes mellitus (DM) is an independent risk factor for heart disease and its underlying mechanisms are unclear. Increased expression of diabetic marker miR-29 family miRNAs (miR-29a, b and c) that suppress the pro-survival protein Myeloid Cell Leukemia
Nicholas Arnold, Purushotham Reddy Koppula, Rukhsana Gul, Christian Luck, Lakshmi Pulakat   +4 more
doaj   +1 more source

Adiponectin Dysregulation and Insulin Resistance in Type 1 Diabetes [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2012
Type 1 diabetes (T1D) is associated with insulin resistance despite elevated levels of the insulin-sensitizing protein adiponectin. Whether the expected positive correlation between adiponectin and insulin sensitivity is preserved in a T1D population is unknown.We measured the correlation between total and high-molecular-weight (HMW) adiponectin and ...
Rocio I, Pereira, Janet K, Snell-Bergeon, Christopher, Erickson, Irene E, Schauer, Bryan C, Bergman, Marian, Rewers, David M, Maahs   +6 more
openaire   +2 more sources

Infection and Immunometabolism in the Central Nervous System: A Possible Mechanistic Link Between Metabolic Imbalance and Dementia

Frontiers in Cellular Neuroscience, 2021
Metabolic syndromes are frequently associated with dementia, suggesting that the dysregulation of energy metabolism can increase the risk of neurodegeneration and cognitive impairment.
Noriko Shinjyo, Noriko Shinjyo, Kiyoshi Kita, Kiyoshi Kita   +3 more
doaj   +1 more source

An Anti-Inflammatory Sterol Decreases Obesity-Related Inflammation-Induced Insulin Resistance and Metabolic Dysregulation

Mediators of Inflammation, 2013
Obesity-related inflammation-induced insulin resistance and metabolic dysregulation were investigated in retrospective analysis of placebo hematologic and metabolic laboratory data from trials associated with increasing chronic low-grade inflammation and
Chris L. Reading, Jaime Flores-Riveros, Dwight R. Stickney, James M. Frincke   +3 more
doaj   +1 more source

Dysregulation of insulin-sensitive glucose transporters during insulin resistance-induced atrial fibrillation

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2018
Diabetes has been identified as major risk factor for atrial fibrillation (AF). Although glucose and insulin disturbances during diabetes may affect atrial function, little is known about the potential pathogenic role of glucose metabolism during AF. Glucose transport into the cell via glucose transporters (GLUTs) is the rate-limiting step of glucose ...
Zahra, Maria, Allison R, Campolo, Benjamin J, Scherlag, Jerry W, Ritchey, Véronique A, Lacombe   +4 more
openaire   +2 more sources