Results 31 to 40 of about 1,795,545 (198)

The Impact of a Pure Protein Load on the Glucose Levels in Type 1 Diabetes Patients Treated with Insulin Pumps

International Journal of Endocrinology, 2015
We aimed to estimate the impact of ingestion of a pure protein load on the glucose levels in T1DM patients treated with insulin pumps. We examined 10 T1DM patients (6 females, mean age—32.3 years, mean HbA1c—6.8%) treated with insulin pumps equipped with
Tomasz Klupa, Teresa Benbenek-Klupa, Bartlomiej Matejko, Sandra Mrozinska, Maciej T. Malecki   +4 more
doaj   +1 more source

Deformable Nanovesicle-Loaded Gel for Buccal Insulin Delivery

Pharmaceutics, 2022
Deformable nanovesicles (DNVs) have been widely used in oral mucosal delivery studies of biomolecular drugs. However, their development for oral mucosal preparations has been limited by their physical and chemical instability, the need for small oral volumes, and the complexity of the oral microenvironment.
Yiyue Guo, Yuqi Yang, You Xu, Yingying Meng, Jun Ye, Xuejun Xia, Yuling Liu   +6 more
openaire   +3 more sources

Insulin-Loaded Barium Salt Particles Facilitate Oral Delivery of Insulin in Diabetic Rats [PDF]

Pharmaceutics, 2020
Oral delivery is considered as the most preferred and yet most challenging mode of drug administration; especially a fragile and sensitive peptide like insulin that shows extremely low bioavailability through the gastro-intestinal (GIT) route. To address this problem, we have designed a novel drug delivery system (DDS) using precipitation-induced ...
Rahela Zaman, Md. Emranul Karim, Iekhsan Othman, Anuar Zaini, Ezharul Hoque Chowdhury   +4 more
openaire   +3 more sources

Gene expression patterns of insulin-like growth factor 1, insulin-like growth factor 2 and insulin-like growth factor binding protein 3 in human placenta from pregnancies with intrauterine growth restriction [PDF]

, 2011
Introduction: In this study, we compared insulin-like growth factor (IGF)-gene expression patterns and characteristics of glucose and insulin metabolism in human placenta from pregnancies with or without intrauterine growth restriction (IUGR).
Tóth, Katalin, Börzsönyi Balázs, Demendi Csaba, Balázs Börzsönyi, Börzsönyi, Balázs, Tóth Katalin, János Rigó Jr, Pajor, Attila, Rigó, János, Joó József, Gábor, Zsolt Nagy, Csaba Demendi, Rigó János, Pajor Attila, Mónika Csanád, Katalin Tóth, Demendi, Csaba, Csanád, Mónika, Nagy, Zsolt, Attila Pajor, József Gábor Joó, Nagy Zsolt, Csanád Mónika, Joó József Gábor   +23 more
core   +1 more source

Effect of low glycemic load diet with and without wheat bran on glucose control in gestational diabetes mellitus: A randomized trial

Indian Journal of Endocrinology and Metabolism, 2013
Background: A low-glycemic index diet is effective in blood glucose control of diabetic subjects, reduces insulin requirement in women with gestation diabetes mellitus (GDM) and improves pregnancy outcomes when used from beginning of the second trimester.
Ahmad Afaghi, Laleh Ghanei, Amir Ziaee
doaj   +1 more source

Hypothesis: ‘Vasocrine’ signalling from perivascular fat - a mechanism linking insulin resistance and vascular disease [PDF]

, 2005
Adipose tissue expresses cytokines which inhibit insulin signalling pathways in liver and muscle. Obesity also results in impairment of endothelium-dependent vasodilatation to insulin. We propose a vasoregulatory role for local deposits of fat around the
Eringa, E., Stehouwer, C.D.A.; id_orcid, Stehouwer, Coen D.A., Yudkin, J.S., Yudkin, John S.   +4 more
core   +1 more source

The Carnivore Connection Hypothesis: Revisited

Journal of Obesity, 2012
The “Carnivore Connection” hypothesizes that, during human evolution, a scarcity of dietary carbohydrate in diets with low plant : animal subsistence ratios led to insulin resistance providing a survival and reproductive advantage with selection of genes
Jennie C. Brand-Miller, Hayley J. Griffin, Stephen Colagiuri   +2 more
doaj   +1 more source

Impaired early‐phase suppression of glucagon secretion after glucose load is associated with insulin requirement during pregnancy in gestational diabetes

Journal of Diabetes Investigation, 2020
Aims/Introduction The role of glucagon abnormality has recently been reported in type 2 diabetes; however, its role in gestational diabetes mellitus (GDM) is still unknown.
Ichiro Horie, Ai Haraguchi, Ayako Ito, Aya Nozaki, Shoko Natsuda, Satoru Akazawa, Yoshitaka Mori, Takao Ando, Ai Higashijima, Yuri Hasegawa, Atsushi Yoshida, Kiyonori Miura, Hideaki Masuzaki, Atsushi Kawakami, Norio Abiru   +14 more
doaj   +1 more source

Effects 0f Aliskiren on the Absorption of Monosaccharides in Animal Model of Fructose-induced Metabolic Syndrome

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2018
The renin angiotensin system (RAS) was involved in various metabolic processes including insulin secretion, carbohydrate absorption and proliferation of adipose tissue. This study aims to evaluate the effects of aliskiren on the absorption of glucose in
Tavga Ahmed Aziz, Zheen Orahman Ahmed, Rbab Mohammed Utba, Saad Abdulrahman Hussain   +3 more
doaj   +1 more source

Swimming training potentiates the recovery of femoral neck strength in young diabetic rats under insulin therapy

Clinics, 2019
OBJECTIVE: To test whether swimming training benefits femoral neck strength in young diabetic rats under insulin therapy. METHODS: A total of 60 male Wistar rats (age: 40 days) were divided equally into the following six groups: control sedentary ...
Gilton de Jesus Gomes, Ricardo Junqueira Del Carlo, Márcia Ferreira da Silva, Daise Nunes Queiroz da Cunha, Edson da Silva, Karina Ana da Silva, Miguel Araújo Carneiro-Junior, Thales Nicolau Prímola-Gomes, Antônio José Natali   +8 more
doaj   +1 more source