Results 61 to 70 of about 222,467 (377)

EFFECTS OF INSULIN, GLUCAGON, AND INSULIN/GLUCAGON INFUSIONS ON LIVER MORPHOLOGY AND CELL DIVISION AFTER COMPLETE PORTACAVAL SHUNT IN DOGS [PDF]

, 1976
Insulin, glucagon, and insulin/glucagon mixtures have been infused for four days into the left portal vein of dogs after portacaval shunt. In the left but not the right liver lobes, insulin alone reduced atrophy, preserved hepatocyte ultrastructure, and ...
Blackard, Bollman, Bucher, Child, Eck, Felig, Felig, Field, Fisher, Fisher, Hahn, Holley, Izzo, Leffert, Loud, Madison, Mann, Marchioro, Marchioro, Marchioro, Meyer, Popper, Reaven, Rous, Rubin, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Tchobroutsky, Warren, Wembren, Younger   +36 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Insulin Allergy to Detemir Followed by Rapid Onset of Diabetic Ketoacidosis: A Case Report and Literature Review

Frontiers in Endocrinology, 2022
The management of diabetes mellitus in an insulin-dependent patient is challenging in the setting of concomitant antibody-mediated-insulin hypersensitivity.
Chong Boon Teo, Pek Yan Tan, Shan Xian Lee, Joan Khoo, Jun Guan Tan, Su Fen Ang, Sze Hwa Tan, Tunn Lin Tay, Eberta Tan, Su Chi Lim, Su Chi Lim, Bernhard O. Boehm, Bernhard O. Boehm, Bernhard O. Boehm, Wann Jia Loh   +14 more
doaj   +1 more source

COMPARISON OF DIABETES-RELATED QUALITY OF LIFE FOR LATE ADOLESCENTS WITH TYPE 1 DIABETES USING INSULIN PUMP THERAPY VS. MULTIPLE DAILY INJECTIONS [PDF]

, 2012
poster abstractTraditionally, multiple daily injections (MDI) have been used to manage insulin levels, while insulin pump therapy is rising as an option for treat-ment.
Hanna, Kathleen M., Woods, Jasmine
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Becoming Autonomous and Integrating Insulin Pump Therapy into Life: A Qualitative Analysis of Adolescent Experiences with Type 1 Diabetes Management

Diabetology
Objectives: This study explored perceptions, experiences, and outcomes associated with the choice of insulin therapies among pediatric patients with type 1 diabetes mellitus (T1D).
Eleni C. Tzavela, Lydia Kossiva, Irine-Ikbale Sakou, George Paltoglou, Adamantini Plarinou, Spyridon Karanasios, Kyriaki Karavanaki   +6 more
doaj   +1 more source

Continual Evolution: The Experience Over Three Semesters of a Librarian Embedded in an Online Evidence-Based Medicine Course for Physician Assistant Students [PDF]

, 2011
This column examines the experience, over three years, of a librarian embedded in an online Epidemiology and Evidence-based Medicine course, which is a requirement for students pursing a Master of Science in Physician Assistant Studies at Pace University.
Kealey, Shannon
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Insulin therapy and dietary adjustments to normalize glycemia and prevent nocturnal hypoglycemia after evening exercise in type 1 diabetes: a randomized controlled trial [PDF]

, 2014
Introduction Evening-time exercise is a frequent cause of severe hypoglycemia in type 1 diabetes, fear of which deters participation in regular exercise.
Campbell, Matthew, Walker, Mark, Bracken, Richard, Turner, David, Stevenson, Emma, Gonzalez, Javier, Shaw, James, West, Dan   +7 more
core   +4 more sources