Results 211 to 220 of about 794,012 (351)

Structure and activation of the Drosophila insulin receptor by three Drosophila insulin-like peptides. [PDF]

Nat Commun
Cai K, Ng M, Yamamoto RR, Hossain MA, Hall C, Wade JD, Tatar M, Choi E, Bai XC.   +8 more
europepmc   +1 more source

Isoproterenol modulates insulin activation of insulin receptor kinase in intact rat adipocytes [PDF]

, 1988
Klein, H. H., Matthaei, S., Scriba, Peter Christian   +2 more
core  

Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages

Advanced Science, EarlyView.
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu, Yiyu‐Li Tang, Zong‐Bo Zhang, Ya‐Hong Tan, Si‐Hui Lin, Ni‐Ya Wang, Jin‐Nan Li, Zhi‐Jie Pan, Jian‐Feng Li, Jing‐Fei Huang, Yu‐Qiang Ding, Chun‐Ming Guo, Lin Xu, Cheng Peng, Qi‐Xin Zhou   +14 more
wiley   +1 more source

Insulin binding and insulin-dependent phosphorylation of the insulin receptor solubilized from human erythrocytes.

, 1983
Florin Grigorescu, Morris F. White, C. Ronald Kahn   +2 more
openalex   +1 more source

Hepatocyte‐Derived Extracellular Vesicles Deliver miR‐328‐3p to Trigger PP2A‐B56δ–Mediated p‐NLRP3S295‐Dependent Metaflammation in Macrophages upon Microcystin‐LR Exposure

Advanced Science, EarlyView.
Hepatocyte‐derived extracellular vesicles deliver miR‐328‐3p to trigger PP2A‐B56δ–mediated p‐NLRP3S295‐dependent metaflammation in macrophages upon microcystin‐LR exposure. 2‐DG, 2‐deoxy‐D‐glucose. B56δ, protein phosphatase 2A‐B56δ. ER, endoplasmic reticulum. iHD‐EV, inducible hepatocyte‐derived extracellular vesicles. IP3R, inositol 1,4,5‐triphosphate
Jia‐Shen Wu, Xin‐Yu Zhang, Xin‐Yu Ma, Yue‐Yue Wei, Lei‐Lei Wang, Ze‐Bang Du, Xiao‐Gang Xia, Lin Che, Dong‐Bei Guo, Han‐Ying Zheng, You‐Liang Yao, Wen‐Gang Li, Yu‐Chun Lin, Zhong‐Ning Lin   +13 more
wiley   +1 more source

Modeling cell line-specific recruitment of signaling proteins to the insulin-like growth factor 1 receptor

, 2018
Keesha E. Erickson, Oleksii S. Rukhlenko, M. Shahinuzzaman, Kalina P. Slavkova, Yen Ting Lin, Edward C. Stites, Marian Anghel, Richard G. Posner, Dipak Barua, Boris Ν. Kholodenko, William S. Hlavacek   +10 more
openalex   +2 more sources

PD‐1 Inhibits CD4+ TRM‐Mediated cDC1 Mobilization via Suppressing JAML in Human NSCLC

Advanced Science, EarlyView.
CD4+ tissue‐resident memory T cells (TRMs) in non‐small cell lung cancer recruit conventional type 1 dendritic cells via XCL1‐XCR1 signaling, orchestrating antitumor immunity. The costimulatory molecule JAML is essential for this process. PD‐1 blockade restores JAML expression and cDC1 mobilization, while JAML agonists synergize with anti‐PD‐1 therapy,
Zheyu Shao, Qinyuan Liu, Zhongwei Xin, Zhiyao Zhou, Mingjie Lin, Di Chen, Zhixing Hao, Yongyuan Chen, Wenxuan Wu, Shuyang Zhang, Xiaoke Chen, Xia Xu, Jinfan Li, Wei Lin, Yuhao Lu, Dang Wu, Pin Wu   +16 more
wiley   +1 more source

Structural mechanism of insulin receptor activation by a dimeric aptamer agonist. [PDF]

Exp Mol Med
Kim J, Na H, Choi SY, Oh EJ, Lee H, Ryu SH, Yunn NO, Cho Y.   +7 more
europepmc   +1 more source

Increased galanin-galanin receptor 1 signaling, inflammation, and insulin resistance are associated with affective symptoms and chronic fatigue syndrome due to Long COVID [PDF]

Wasim Talib Mahdi Al Masoodi, Sami Waheed Radhi, Habiba Khdair Abdalsada, Mutian Niu, Hussein Kadhem Al‐Hakeim, Michaël Maes   +5 more
openalex   +1 more source

Osteoblast-specific Knockout of the Insulin-like Growth Factor (IGF) Receptor Gene Reveals an Essential Role of IGF Signaling in Bone Matrix Mineralization [PDF]

, 2002
Mei Zhang, Shouhong Xuan, Mary Bouxsein, D. von Stechow, Nagako Akeno, M.-C. Faugere, Hartmut H. Malluche, Guisheng Zhao, Clifford J. Rosen, Argiris Efstratiadis, Thomas L. Clemens   +10 more
openalex   +1 more source