Results 261 to 270 of about 794,012 (351)

Lentivirus-mediated downregulation of hypothalamic insulin receptor expression

, 2007
Claudia A. Grillo, Kellie L. Tamashiro, Gerardo G. Piroli, Susan J. Melhorn, Justin T. Gass, Ryan J. Newsom, Leah R. Reznikov, Amy C. Smith, Steven P. Wilson, R.R. Sakai, Lawrence P. Reagan   +10 more
openalex   +1 more source

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source

Activation of the Insulin Receptor by <i>Sarcopoterium spinosum</i> Extract and Identification of Sarcocyanidin A as a Novel Active Compound. [PDF]

ACS Omega
Wollman A, Hasib Afana R, Carmeli S, Rosenzweig T.   +3 more
europepmc   +1 more source

Insulin Receptor-Related Receptor [PDF]

, 2020
openaire   +1 more source

Serotonin Receptor 2C and Insulin Secretion

, 2013
Qiang Zhang, Yunxia Zhu, Wenbo Zhou, Lu Gao, Yuan Li, Xiao Han   +5 more
openalex   +2 more sources

FSTL1 Orchestrates Metabolic‐Epigenetic Crosstalk: Glycolysis‐Dependent H3K18 Lactylation Drives Cartilage Fibrosis in Osteoarthritis

Advanced Science, EarlyView.
FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu, Yunyuan Yu, Guangrong Yin, Huiqun Hu, Shishuo Li, Yuting Tang, Yimin Liu, Maoyuan Li, Liang liang Wang, Chao Xu, Gongyin Zhao, Baojun Zhou, Yuji Wang   +12 more
wiley   +1 more source

Impaired insulin receptor function alters psychiatric behaviors without affecting circadian rhythms in a mouse model of Alzheimer's disease. [PDF]

Geriatr Gerontol Int
Izuo N, Yokote K, Shimizu T.
europepmc   +1 more source

Activation of the Insulin Receptor by Sarcopoteriumspinosum Extract and Identificationof Sarcocyanidin A as a Novel Active Compound

Ayala Wollman (21027499), Rania Hasib Afana (21027502), Shmuel Carmeli (588039), Tovit Rosenzweig (5228105)   +3 more
openalex   +1 more source

Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors.

, 1991
Judith L. Treadway, B D Morrison, Maria A. Soos, Kenneth Siddle, Jerrold M. Olefsky, A. Ullrich, Donald A. McClain, Jeffrey E. Pessin   +7 more
openalex   +2 more sources

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source