Physiological ReportsEndurance‐oriented exercise typically enhances insulin action in skeletal muscle; however, relatively little is known about the impact of resistance exercise. In the present study, insulin action was determined in primary human skeletal muscle stem cells
Polina Krassovskaia +18 more
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Prediagnostic markers of insulin resistance and prostate cancer risk and death: A pooled study [PDF]
, 2023 Sylvia H. J. Jochems +4 more
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The yield of early-pregnancy homeostasis of model assessment -insulin resistance (HOMA-IR) for predicting gestational diabetes mellitus in different body mass index and age groups [PDF]
, 2023 Sima Hashemipour +9 more
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The Effects of Engeletin on Insulin Resistance Induced in Human HepG2 Liver Cells
Current Issues in Molecular BiologyIn this study, we aimed to investigate the effect of Engeletin (ENG) on insulin resistance and the associated oxidative cell damage in human HepG2 liver cells. The cells were grown in a cell culture medium, and insulin resistance was induced.
Erdem Toktay +5 more
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Insulin resistance drives hepatic de novo lipogenesis in nonalcoholic fatty liver disease [PDF]
, 2019 Gordon I. Smith +13 more
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Insulin Resistance and Truncal Obesity as Important Determinants of the Greater Incidence of Diabetes in Indian Asians and African Caribbeans Compared With Europeans [PDF]
, 2012 Therese Tillin +8 more
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Journal of the American Heart Association: Cardiovascular and Cerebrovascular DiseaseBackground Insulin resistance as a significant vascular risk factor has been studied in relation to cerebral small vessel disease (SVD). Evidence suggests that insulin resistance might trigger high blood pressure (BP).
Mengyuan Zhou +13 more
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Role of obesity in development of insulin resistance: A review
مجلة جامعة الزيتونة, 2022 The relationship between obesity and insulin resistance is widely accepted. This relationship represents several major health hazards including morbid obesity and insulin resistance complications worldwide.
Fathi Hudoud
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Mechanism of Insulin Resistance.
Nippon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics, 1999 インスリン抵抗性の成因は遺伝素因, 肥満などの生活習慣, 高血糖それ自体に大別される. 肥満に伴うインスリン抵抗性は肥大した脂肪細胞から分泌されるTNF-αや遊離脂肪酸 (FFA) が関与している. インスリン抵抗性の分子レベルでの共通の特徴は, (1)インスリン受容体チロシンキナーゼ・P13キナーゼ活性の低下, (2)GLUT4トランスロケーションと糖取り込み低下, (3)グリコーゲン合成酵素活性低下である. インスリン抵抗性は, 膵β細胞のインスリン分泌能や増殖能に障害のある場合には, 2型糖尿病の強力な発症要因となる. 最近, 糖代謝に関するインスリン作用に加えて, 血管や腎でのインスリン作用が解明されつつある.
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Non-alcoholic fatty liver disease is associated with insulin resistance and lipid accumulation product in women with polycystic ovary syndrome [PDF]
, 2016 Djuro Μacut +7 more
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