Inflammation and insulin resistance. [PDF]
Diabetes Care, 2003This Is the second of two articles describing a symposium on the relationship between inflammation and insulin resistance that was held in Niagra Falls, NY, 20–21 September 2002.
Z. Bloomgarden
semanticscholar +6 more sources
Use of the SGLT2 inhibitor canagliflozin for control of refractory equine hyperinsulinemia and laminitis [PDF]
Open Veterinary Journal, 2022Background: Hyperinsulinemia associated with pituitary pars intermedia dysfunction (PPID) and/or equine metabolic syndrome (EMS) is well documented to put horses at high risk of laminitis.
Eleanor M. Kellon, Kathleen M. Gustafson
doaj +1 more source
Hypertriglyceridemia in equines with refractory hyperinsulinemia treated with SGLT2 inhibitors
Open Veterinary Journal, 2023Background: Sodium-Glucose CoTransporter-2 [SGLT2] inhibitors, the -flozin group of drugs, which block glucose reuptake in the renal proximal tubule, are being increasingly used off-label to treat horses with refractory hyperinsulinemia. After two years
Eleanor M. Kellon, Kathleen M. Gustafson
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Possible dysmetabolic hyperferritinemia in hyperinsulinemic horses [PDF]
Open Veterinary Journal, 2019Background: Hyperinsulinemia associated with equine metabolic syndrome (EMS) and pituitary pars intermedia dysfunction (PPID) is a risk factor for laminitis.
Eleanor M. Kellon, Kathleen M. Gustafson
doaj +1 more source
Insulin resistance in children [PDF]
Current Opinion in Pediatrics, 2019Purpose of review Insulin resistance (IR) is a clinical condition due to the decline in the efficiency of insulin promoting glucose uptake and utilization. The aim of this review is to provide an overview of the current knowledge on IR in children, focusing on its physiopathology, the most appropriate methods of measurement of ...
Tagi V. M., Giannini C., Chiarelli F.
openaire +6 more sources
Insulin Resistance: From Mechanisms to Therapeutic Strategies
Diabetes & Metabolism Journal, 2021Insulin resistance is the pivotal pathogenic component of many metabolic diseases, including type 2 diabetes mellitus, and is defined as a state of reduced responsiveness of insulin-targeting tissues to physiological levels of insulin.
Shin-Hae Lee, Shi-Young Park, C. Choi
semanticscholar +1 more source
Clinical analysis of insulin resistance in liver cirrhosis patients
Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023Objective·To investigate the insulin resistance in liver cirrhosis patients.Methods·Patients with liver cirrhosis from Xinhua Hospital,Shanghai Jiao Tong University School of Medicine in 2013‒2017 were retrospectively assessed.
SHI Cuicui+4 more
doaj +1 more source
Obesity and Cardiovascular Risk: Variations in Visfatin Gene Can Modify the Obesity Associated Cardiovascular Risk. Results from the Segovia Population Based-Study. Spain. [PDF]
PLoS ONE, 2016OBJECTIVES:Our aim was to investigate if genetic variations in the visfatin gene (SNPs rs7789066/ rs11977021/rs4730153) could modify the cardiovascular-risk (CV-risk) despite the metabolic phenotype (obesity and glucose tolerance).
María Teresa Martínez Larrad+6 more
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DMRT2 Interacts With FXR and Improves Insulin Resistance in Adipocytes and a Mouse Model
Frontiers in Endocrinology, 2022Insulin resistance (IR) plays a critical role in cardiovascular diseases and metabolic diseases. In this study, we identified the downregulation of DMRT2 in adipose tissues from insulin-resistant subjects through bioinformatics analysis and in an insulin-
Jing Tao+11 more
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