Results 111 to 120 of about 4,252,621 (405)
Analysis of Association between Vitamin D Deficiency and Insulin Resistance
Nutrients, 2019 Recent evidence revealed extra skeleton activity of vitamin D, including prevention from cardiometabolic diseases and cancer development as well as anti-inflammatory properties.
Izabela Szymczak-Pajor, A. Śliwińska
semanticscholar +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Journal of Diabetes Research, 2017 Aim. Smoking is a major risk factor for diabetes mellitus, mainly due to decreased insulin secretion and increased insulin resistance. However, there has been little research on the effects of smoking cessation period on changes in insulin resistance. In
Ko-Woon Kim +5 more
doaj +1 more source
The Role of Insulin Resistance in Diabetic Patients with Chronic Liver Disease [PDF]
, 2008 Background: The association between diabetes and chronic liver disease has been well documented. However, the mechanism remains unknown. The aim of this study was to investigate the insulin resistance in chronic liver disease and normal liver in diabetic
Bayupurnama, P. (Putut) +3 more
core +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Arthritis Care &Research, EarlyView.Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry +2 more
wiley +1 more source
Determinants of Maternal Insulin Resistance during Pregnancy: An Updated Overview
Journal of Diabetes Research, 2019 Insulin resistance changes over time during pregnancy, and in the last half of the pregnancy, insulin resistance increases considerably and can become severe, especially in women with gestational diabetes and type 2 diabetes.
U. Kampmann +3 more
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun +8 more
wiley +1 more source
Prolonged exposure to insulin might cause epigenetic alteration leading to insulin resistance
FEBS Open BioGlucose homeostasis is maintained by insulin. Insulin resistance is caused by multiple factors including hereditary factors and diet. The molecular mechanism underlying insulin resistance (IR) is not completely understood. Hyperinsulinemia often precedes
Shehnaz Bano +6 more
doaj +1 more source
Changes in insulin and insulin signaling in Alzheimer\u27s disease: Cause or consequence? [PDF]
, 2016 Individuals with type 2 diabetes have an increased risk for developing Alzheimer’s disease (AD), although the causal relationship remains poorly understood. Alterations in insulin signaling (IS) are reported in the AD brain.
Holtzman, David M +2 more
core +2 more sources
The Role of Ceramides in Insulin Resistance
Frontiers in Endocrinology, 2019 Resistance to insulin is a pathophysiological state related to the decreased response of peripheral tissues to the insulin action, hyperinsulinemia and raised blood glucose levels caused by increased hepatic glucose outflow.
E. Sokołowska, A. Błachnio-Zabielska
semanticscholar +1 more source