Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus. [PDF]
Orville Kolterman+6 more
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An Ultrapotent, Ultraeconomical, Antifreeze Polypeptide
Simple and inexpensive polypeptides composed of random copolymers of alanine and glutamic acid are effective antifreezes for applications in foods and biomedicine. The polypeptides, inspired by natural extremophile proteins, inhibit the growth of large ice crystals and prevent damage to sensitive biologics.
Thomas J. McPartlon+5 more
wiley +1 more source
Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemia. [PDF]
Boris Draznin+5 more
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A schematic illustration of how noble metals can be used to create nanoparticles (NPs) or nanoclusters (NCs). Noble metal NPs, due to their plasmonic properties, enable photothermal therapy and surface‐enhanced Raman scattering (SERS). In contrast, NCs, which lack a plasmonic resonance band, exhibit fluorescence, making them ideal for bioimaging ...
David Esporrín‐Ubieto+3 more
wiley +1 more source
Studies on the mechanism of insulin resistance in the liver from humans with noninsulin-dependent diabetes. Insulin action and binding in isolated hepatocytes, insulin receptor structure, and kinase activity. [PDF]
J F+9 more
openalex +1 more source
Implantable Light‐Powered Human Designer Cells for Electrical Energy Generation
Inspired by the eel's electric organ, a miniature implantable biohybrid device is developed to generate electricity under light activation. The device utilizes a light‐dependent ion gradient formation that induced by genetically engineered human designer cells that express light‐sensitive membrane ion channels and proton pumps, working in synergy with ...
Shuai Xue+5 more
wiley +1 more source
Nanostructured Protein Surfaces Inspired by Spider Silk
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley +1 more source
Reversal of insulin resistance in type I diabetes after treatment with continuous subcutaneous insulin infusion. [PDF]
I. Lager+3 more
openalex +1 more source
Characterization of insulin receptors in patients with the syndromes of insulin resistance and acanthosis nigricans [PDF]
Robert S. Bar+4 more
openalex +1 more source