Results 261 to 270 of about 3,853,066 (390)
Insulin resistance causes inflammation in adipose tissue
Mitsugu Shimobayashi+14 more
semanticscholar +1 more source
Gut Microbiota‐Butyrate‐PPARγ Axis Modulates Adipose Regulatory T Cell Population
This study identifies the indispensable role of gut microbiota in the maintenance of ST2+ adipose Treg cell population, and defines gut microbiota‐derived butyrate as an endogenous PPARγ agonist, modulating adipose Treg cell populations via promoting PPARγ activation. Butyrate or fiber supplementation restores the VAT ST2+ Treg population in obese mice
Banru Chen+16 more
wiley +1 more source
Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy
Guanghong Jia, V. DeMarco, J. Sowers
semanticscholar +1 more source
This study interrogated the single‐cell transcriptome of immune cells across multiple anatomical sites in ovarian cancer patients and identified a novel subset of macrophages that are enriched in ascites and overexpressed the lipid droplet protein PLIN2.
Hui Luo+20 more
wiley +1 more source
Local patterns of genetic sharing between neuropsychiatric and insulin resistance-related conditions. [PDF]
Fanelli G+27 more
europepmc +1 more source
Embelin cotargets SHP2 to disrupt the SHP2/GRB2/SOS complex, inhibiting cancer‐related signaling pathways such as MAPK, (PI3K)/AKT pathway, and XIAP to induce apoptosis signaling pathway, respectively, leading to synthetic lethality in KRAS‐mutant NSCLC cells both in vivo and in vitro.
Nai‐jie Fu+8 more
wiley +1 more source
Advanced glycation end-product intake predicts insulin resistance in a sex-dependent fashion. [PDF]
Sergi D+7 more
europepmc +1 more source
hESCs‐derived Organoids Achieve Liver Zonation Features through LSEC Modulation
This article addresses the absence of zonation features in current organoid models by co‐culturing human embryonic stem cell‐derived hepatocytes with liver sinusoidal endothelial cells exhibiting distinct zonal characteristics. It demonstrates that differential WNT2 signaling from endothelial cells modulates hepatocyte zonation and metabolic functions,
Yuying Zhang+13 more
wiley +1 more source
The association between thyroid function and insulin resistance as measured by the metabolic score for insulin resistance (METS-IR): insights from NHANES 2007-2012. [PDF]
Safari F, Nabavizadeh A, Vardanjani HM.
europepmc +1 more source