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Insulin-dependent regulation of the insulin-sensitivity of adipocytes

Nature, 1978
THE responsiveness of a target organ to insulin is evidently subject to regulation. This phenomenon is best demonstrated by the presence in man and animals of insulin-resistant states1–4. Since these states are usually accompanied by elevations in plasma insulin levels, a role for insulin in the modulation of insulin-sensitivity of target organs has ...
J N, Livingston   +2 more
openaire   +2 more sources

Vitamin D, glucose, insulin, and insulin sensitivity

Nutrition, 2008
This review examines available evidence of links between abnormalities of glucose and insulin metabolism and vitamin D deficiency. Possible mechanisms of action of vitamin D include stimulation of insulin secretion and effects on insulin sensitivity.
Tai, K.   +3 more
openaire   +3 more sources

Influence of exercise on insulin sensitivity

Journal of Cardiovascular Risk, 1995
An important determinant of insulin sensitivity in humans, the insulin-induced glucose uptake in skeletal muscle (directed into glycogen synthesis), has been found to be markedly enhanced in endurance-trained individuals compared with sedentary controls.
openaire   +2 more sources

Insulin sensitivity and premenstrual syndrome

Current Diabetes Reports, 2004
Maintaining normal blood glucose levels is a constant challenge for women with diabetes. Anecdotal reports reveal that many women question if menstrual cycle phases may affect their blood glucose levels. However, results from studies investigating the effect of the menstrual cycle on insulin sensitivity in diabetic women have been conflicting.
Kimberly K, Trout, Karen L, Teff
openaire   +2 more sources

Exercise and Insulin Sensitivity: A Review

International Journal of Sports Medicine, 2000
Physical activity has a beneficial effect on insulin sensitivity in normal as well as insulin resistant populations. A distinction should be made between the acute effects of exercise and genuine training effects. Up to two hours after exercise, glucose uptake is in part elevated due to insulin independent mechanisms, probably involving a contraction ...
L B, Borghouts, H A, Keizer
openaire   +2 more sources

[Insulin sensitizers].

Revue medicale de Liege, 2005
Insulin resistance has a genetic background and its phenotypic expression is triggered by fat diet, lack of physical activity and obesity. It provokes a stress on B cells, tends to increase blood glucose levels, is intimately associated with the metabolic syndrome and represents a major cardiovascular risk factor.
A J, Scheen, N, Paquot
openaire   +1 more source

Fatty acids and insulin sensitivity

Current Opinion in Clinical Nutrition and Metabolic Care, 2008
Given the pathophysiological importance of insulin resistance, the potential impact of dietary fatty acids is highly relevant. The effects of different types of dietary fatty acids on insulin sensitivity in humans are discussed, with focus on recent controlled studies.Observational studies assessing fatty acid composition in serum or tissues suggest ...
openaire   +2 more sources

The aetiology and molecular landscape of insulin resistance

Nature Reviews Molecular Cell Biology, 2021
David E James   +2 more
exaly  

The many actions of insulin in skeletal muscle, the paramount tissue determining glycemia

Cell Metabolism, 2021
Lykke Sylow   +2 more
exaly  

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