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Biological Trace Element Research, 1992
Many studies have shown that zinc deficiency could decrease the response to insulin. In genetically diabetic animals, a low zinc status has been observed contrary to induced diabetic animals. The zinc status of human patients depends on the type of diabetes and the age.
P, Faure +5 more
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Many studies have shown that zinc deficiency could decrease the response to insulin. In genetically diabetic animals, a low zinc status has been observed contrary to induced diabetic animals. The zinc status of human patients depends on the type of diabetes and the age.
P, Faure +5 more
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Modulation of insulin signalling by insulin sensitizers
Biochemical Society Transactions, 2005Insulin resistance is a hallmark of Type II diabetes. It is well documented that insulin sensitizers such as peroxisome-proliferator-activated receptor γ agonists and aspirin improve insulin action in vivo. The detailed mechanisms by which the insulin sensitizers promote insulin signalling, however, are not completely understood and remain somewhat ...
G, Jiang, B B, Zhang
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Measures of Insulin Sensitivity
Clinics in Laboratory Medicine, 2006Many approaches may be taken in the assessment of insulin sensitivity in humans. The euglycemic hyperinsulinemic glucose clamp and measurement of steady-state plasma glucose are direct but time- and resource-intensive approaches. Alternative approaches, including calculations based on fasting plasma insulin and glucose levels or analyses of glucose and
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Caffeine and Insulin Sensitivity
Metabolic Syndrome and Related Disorders, 2005A number of reports have observed that acute caffeine ingestion decreases glucose tolerance and insulin sensitivity, and have raised the question whether its increased consumption throughout the world in the form of coffee and cola beverages might be of public health concern in the development of type 2 diabetes.
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Insulin-sensitive and insulin-resistant variants in NIDDM
Diabetes, 1989To define the sequence of events that is involved in the pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM), we studied 16 NIDDM individuals (15 of 16 Black patients) with a mean age of 44 yr who had been near normoglycemic for 2–91 mo while off of antidiabetic medicine.
M A, Banerji, H E, Lebovitz
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Insulin Sensitivity in Cystic Fibrosis
Diabetes, 1994Cystic fibrosis (CF) patients demonstrate a spectrum of pancreatic β-cell abnormalities. Those with no exocrine insufficiency (NEXO) have normal insulin secretion. Exocrine-insufficient CF patients with overt diabetes (EXO-IT) have impaired insulin secretion and fasting hyperglycemia.
A, Moran +6 more
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Insulin sensitivity in familial hypercholesterolemia
Metabolism, 1993Insulin resistance is found in association with obesity, non-insulin-dependent diabetes mellitus, and essential hypertension, which are all risk factors for atherosclerotic cardiovascular disease. Furthermore, hyperinsulinemia has been reported in familial combined hyperlipoproteinemia and endogenous hypertriglyceridemia. Finally, relatively high serum
GALVAN AQ +7 more
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Familial Clustering of Insulin Sensitivity
Diabetes, 1992This study's objective was to determine whether there is familial clustering of insulin sensitivity (SI) or insulin-independent glucose uptake (SG), which would be evidence that they are genetically determined traits. Outpatients had a 3-h intravenous glucose tolerance test.
Martin, Blaise C +5 more
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Exercise and sensitivity to insulin
Nursing Older People, 2009In type 2 diabetes, insulin is produced but there may be some resistance to it. Resistance is increased by obesity and lack of physical exercise, therefore lifestyle changes are important. The body is more sensitive to insulin for 24-72 hours after exercise.
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Metabolism, 1984
To analyze whether enhanced adiposity in females as compared with males is associated with a decreased sensitivity to insulin, a group of healthy normal weight females (n = 13, age 21 +/- 1 years) and males (n = 11, age 23 +/- 1 year, mean +/- SEM) was studied.
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To analyze whether enhanced adiposity in females as compared with males is associated with a decreased sensitivity to insulin, a group of healthy normal weight females (n = 13, age 21 +/- 1 years) and males (n = 11, age 23 +/- 1 year, mean +/- SEM) was studied.
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