Results 11 to 20 of about 15,083 (188)
Orvosi Hetilap, 2011 Authors present the history of a 56-year-old man who was evaluated for recurrent epigastrial pain. Clinical investigation revealed a 4-cm tumor in the head of the pancreas and a solitary liver metastasis. Pathological examination of the surgically excised pancreatic tumor indicated a moderately differentiated neuroendocrine carcinoma and Ki-67 ...
Miklós, Tóth +5 more
openaire +2 more sources
Clinical characteristics of malignant insulinomas and benign insulinomas [PDF]
Jichu yixue yu linchuangObjective To analyze the differences in clinical indicators between malignant insulinoma and benign insulinoma, in order to provide diagnostic and therapeutic insights for the early detection and diagnosis of malignant insulinoma. Methods A retrospective
LIU Yan, YU Jie, LIU Yiwen, PING Fan, ZHANG Huabing, XU Lingling, LI Yuxiu
doaj +1 more source
BMC Cancer, 2019 Background Insulinoma represents hypoglycemia as a predominant symptom; the autonomic symptoms may be resolved by chronically recurrent hypoglycemia resulting in the persistence of non-specific symptoms alone.
Keiichi Torimoto +10 more
doaj +1 more source
Periodic limb movement disorder: A novel presentation of insulinoma
Annals of Movement Disorders, 2018 Hypoglycemia because of insulinoma can mimic many neurological disorders including movement disorders during sleep. We present a 54-year-old woman who presented with features typical of periodic limb movement disorder and on detailed evaluation was found
Deepa Dash +2 more
doaj +1 more source
Endocrine Connections, 2017 Objective: In adults with hyperinsulinaemic hypoglycaemia (HH), in particular those with insulinoma, the optimal diagnostic and management strategies remain uncertain.
Benjamin G Challis +14 more
doaj +1 more source
Insulinoma: presentación neuro psiquiátrica, caso clínico y revisión de la literatura
Revista Médica Clínica Las Condes, 2022 Resumen: Antecedentes: el insulinoma es un tumor infrecuente que desencadena cuadros de hipoglicemia manifestados por los clásicos síntomas vegetativos y neuroglucopénicos.
Luis Ángel Rodríguez +1 more
doaj +1 more source
Distinctive detection of insulinoma using [18F]FB(ePEG12)12-exendin-4 PET/CT
Scientific Reports, 2021 Specifying the exact localization of insulinoma remains challenging due to the lack of insulinoma-specific imaging methods. Recently, glucagon-like peptide-1 receptor (GLP-1R)-targeted imaging, especially positron emission tomography (PET), has emerged ...
Takaaki Murakami +11 more
doaj +1 more source
A novel diagnostic model for insulinoma
Discover Oncology, 2022 The aim is to describe a simple and feasible model for the diagnosis of insulinoma. This retrospective study enrolled 37 patients with insulinoma and 44 patients with hypoglycemia not due to insulinoma at the First Affiliated Hospital of Guangxi Medical ...
Feng Wang +5 more
doaj +1 more source
Neurofibromatosis and insulinoma [PDF]
Postgraduate Medical Journal, 1995 AbstractA 45-year-old man with neurofibromatosis presented with recurrent seizures due to hypoglycaemia caused by an insulinoma. The attacks were abolished after the successful removal of the insulinoma. This probably represents another example of the association between neurofibromatosis and a tumour consisting of cells with amine-precursor-uptake and
Fung, JWK, Lam, KSL
openaire +3 more sources
Multicomponent Stapling of Glucagon‐Like Peptide‐1 Enables Receptor‐Guided PROTAC Delivery
Angewandte Chemie, EarlyView.We report a stapled glucagon‐like peptide‐1 (GLP‐1) analogue created via multicomponent tryptophan‐mediated Petasis reaction (TMPR). This strategy yields a stabilised peptide with superior helicity and improved potency. Conjugation to a bromodomain‐containing protein 4 (BRD4) degrader creates the first GLP‐1‐guided targeted protein degrader (PROTAC ...
Jan L. Venne +5 more
wiley +2 more sources