ObjectiveCognitive dysfunction is common in insulinoma patients, but the underlying neural mechanisms are less well understood. This study aimed to explore the alterations of intra- and inter-network connectivity patterns associated with patients with ...
Hui Nong +5 more
doaj +1 more source
Pancreatic tumors imaging: an update [PDF]
Currently, ultrasound (US), computed tomography (CT) and Magnetic Resonance imaging (MRI) represent the mainstay in the evaluation of pancreatic solid and cystic tumors affecting pancreas in 80-85% and 10-15% of the cases respectively. Integration of US,
Baccari, Paolo +8 more
core +1 more source
Effect of GTP and Ca2+ on inositol 1,4,5-trisphosphate induced Ca2+ release from permeabilized rat exocrine pancreatic acinar cells [PDF]
The effects of Ca2+ and GTP on the release of Ca2+ from the inositol 1,4,5-trisphosphate (IP3) sensitive Ca2+ compartment were investigated with digitonin permeabilized rat pancreatic acinar cells.
Ammann +30 more
core +1 more source
Accidental exposure to glimepiride from adulterated medication resulting in severe hypoglycaemia
Sulphonylureas are insulinotropic and are not only useful in patients with diabetes but also act in non-diabetic individuals where hypoglycaemia and hyperinsulinism mimic insulinoma.
Annabelle G Hayes +2 more
doaj +1 more source
Recurrent insulinoma in a 10-year-old boy with Down’s syndrome
An insulinoma is a rare tumour with an incidence of four cases per million per year in adults. The incidence in children is not established. There is limited literature available in children with insulinoma, and only one case is reported in association ...
Noman Ahmad +4 more
doaj +1 more source
Clinicopathological and immunohistochemical features of insulinoma in an adult mixed breed dog
Canine insulinoma is a common non-specific neoplasm with high metastasizing ability. Its epidemiology, diagnosis, and treatment are well described. However, its long-term prognosis is considered poor.
Isabeli Joaquim Contel +8 more
doaj +1 more source
The treatment of hyperinsulinemic hypoglycaemia in adults: an update [PDF]
Treatment of hyperinsulinemic hypoglycaemia (HH) is challenging due to the rarity of this condition and the difficulty of differential diagnosis.
A. Colao +6 more
core +1 more source
According to official statistics, malignant insulinomas account for a small fraction of gastroenteropathic endocrine neoplasms, the majority of insulinomas being essentially benign tumours. This paper reports a clinical case of malignant insulin-producing neuroendocrine tumour of the pancreas tail in a 28 year-old woman.
E A, Troshina +5 more
openaire +2 more sources
Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells. [PDF]
Work in our lab is supported by the Medical Research Council [New Investigator Research Grant G1100165 to CA] and Plymouth University [PhD studentship to JB] The final version of record is available at http://www.biochemj.org/bj/456/bj4560417.htmHigh ...
Affourtit, C, Barlow, J
core +2 more sources
Urocortin 3 marks mature human primary and embryonic stem cell-derived pancreatic alpha and beta cells. [PDF]
The peptide hormone Urocortin 3 (Ucn 3) is abundantly and exclusively expressed in mouse pancreatic beta cells where it regulates insulin secretion. Here we demonstrate that Ucn 3 first appears at embryonic day (E) 17.5 and, from approximately postnatal ...
Huising, Mark O +5 more
core +9 more sources

