Results 31 to 40 of about 15,083 (188)

Case Report: Diazoxide-induced diabetic ketoacidosis in a patient with insulinoma

Frontiers in Endocrinology
Definitive management of insulinoma is challenging as curative surgery is associated with a considerable risk of morbidity and mortality. The successful long-term use of diazoxide for patients diagnosed with insulinoma has been described, but rarely, the
Run Ting Chin, Jolene Jiayu Kiew, Khek Yu Ho, Doddabele S. Deepak   +3 more
doaj   +1 more source

Glucose Management during Insulinoma Resection Using Real-Time Subcutaneous Continuous Glucose Monitoring

Case Reports in Anesthesiology, 2018
Insulinoma is a rare neuroendocrine tumor that causes hypoglycemia due to unregulated insulin secretion. Blood glucose management during insulinoma resection is therefore challenging.
Yuki Sugiyama, Chiaki Kiuchi, Maiko Suzuki, Yuki Maruyama, Ryo Wakabayashi, Yasunari Ohno, Shugo Takahata, Takumi Shibazaki, Mikito Kawamata   +8 more
doaj   +1 more source

The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John, Nur Damia Iwani Zulkiflee, Siti Raihanah Shafie, Ramlah George, Melonney Patrick   +4 more
wiley   +1 more source

Accidental exposure to glimepiride from adulterated medication resulting in severe hypoglycaemia

Endocrinology, Diabetes & Metabolism Case Reports, 2022
Sulphonylureas are insulinotropic and are not only useful in patients with diabetes but also act in non-diabetic individuals where hypoglycaemia and hyperinsulinism mimic insulinoma.
Annabelle G Hayes, Mahesh M Umapathysivam, David J Torpy   +2 more
doaj   +1 more source

Clinicopathological and immunohistochemical features of insulinoma in an adult mixed breed dog

Brazilian Journal of Veterinary Pathology, 2023
Canine insulinoma is a common non-specific neoplasm with high metastasizing ability. Its epidemiology, diagnosis, and treatment are well described. However, its long-term prognosis is considered poor.
Isabeli Joaquim Contel, Pedro Pol Ximenes, Fernando Carmona Dinau, Fernanda Barthelson Carvalho de Moura, Giovanna Gati de Souza, Iolanda Simões Braga, Isadora Fernanda Pelaquim, Rafael Torres Neto, Noeme Sousa Rocha   +8 more
doaj   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Cortisol Response to Hypoglycemia in Insulinoma: Clinical and Biochemical Correlates

Endocrinology Research and Practice
Objective: Insulinoma is the most frequent cause of endogenous hyperinsulinemic hypoglycemia. Recurrent hypoglycemia may impair the hypothalamic–pituitary–adrenal axis.
Yusuf Öztürk, Mustafa Kulaksızoğlu
doaj   +1 more source

Pancreatic insulinoma causing hypoglycemic episodes

Journal of Pediatric Surgery Case Reports, 2020
Background: Insulinoma typically has non-specific neuroglycopenic symptoms. It is a neuroendocrine tumor of the pancreas, and leads to recurring hypoglycemic attacks stemming from insulin hypersecretion.
Moaffaq Mahdi, Bassel Almehman, Safi Nassan, Soliman Binyahib   +3 more
doaj   +1 more source

Developmental and Behavioral Effects of Arsenobetaine in Zebrafish (Danio rerio)

Journal of Applied Toxicology, EarlyView.
ABSTRACT Arsenobetaine (AsB) is a prevalent organoarsenical in aquatic environments and is generally regarded as nontoxic. Despite its widespread occurrence, the developmental and neurobehavioral toxicity of AsB has not been systematically investigated.
Sravan Kumar Putnala, Prerita Sharma, Prannav Jain, Samira Leila Baldin, Owen Luo, A. K. M. Munzurul Hasan, Md Helal Uddin, Mahesh Rachamalla, Som Niyogi   +8 more
wiley   +1 more source

Genomic Evolution and Immune Contexture With Therapeutic Relevance in Pancreatic Neuroendocrine Neoplasms

Cancer Science, EarlyView.
Lineage‐dependent immunogenomic landscapes and biologically informed therapy in pancreatic neuroendocrine neoplasms. Pancreatic neuroendocrine neoplasms display lineage‐dependent immunogenomic landscapes, in which genomic alterations, epigenetic states, antigen‐presentation status, immune‐cell infiltration, and suppressive microenvironments co‐evolve ...
Yohei Tabe, Eito Nakagawa, Daisuke Asano, Eriko Katsuta, Daisuke Ban, Shogo Kumagai   +5 more
wiley   +1 more source