Results 51 to 60 of about 18,902 (216)
Incidence and risk factors for insulinoma diagnosed in dogs under primary veterinary care in the UK
Scientific ReportsInsulinoma is the most common pancreatic tumor diagnosed in dogs. This study aimed to report incidence risk, breed predispositions and other demographic risk factors for insulinoma diagnosed in dogs under primary veterinary care in the UK. The VetCompass
Kasper Kraai +5 more
doaj +1 more source
Case Report: Diazoxide-induced diabetic ketoacidosis in a patient with insulinoma
Frontiers in EndocrinologyDefinitive management of insulinoma is challenging as curative surgery is associated with a considerable risk of morbidity and mortality. The successful long-term use of diazoxide for patients diagnosed with insulinoma has been described, but rarely, the
Run Ting Chin +3 more
doaj +1 more source
QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study
Advanced Science, EarlyView.The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda +8 more
wiley +1 more source
Endocrinology, Diabetes & Metabolism Case Reports, 2022 Acanthosis nigricans (AN) is a common dermatosis associated with hyperinsulinemia and insulin resistance. However, AN has been rarely reported in patients with insulinoma, a state of persistent hyperinsulinemia. We present a case of metastatic insulinoma,
Jenny S W Yun +3 more
doaj +1 more source
Case Reports in Anesthesiology, 2018 Insulinoma is a rare neuroendocrine tumor that causes hypoglycemia due to unregulated insulin secretion. Blood glucose management during insulinoma resection is therefore challenging.
Yuki Sugiyama +8 more
doaj +1 more source
Insulinoma Causing Prolonged Hypoglycaemic Coma [PDF]
Journal of Clinical and Diagnostic Research, 2016 Insulinoma is a rare pancreatic endocrine tumour with an incidence of four cases per million per year. A recurrent episode of fasting hypoglycaemia is the most common manifestation of these tumours.
Prabhat Kumar +4 more
doaj +1 more source
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
Cortisol Response to Hypoglycemia in Insulinoma: Clinical and Biochemical Correlates
Endocrinology Research and PracticeObjective: Insulinoma is the most frequent cause of endogenous hyperinsulinemic hypoglycemia. Recurrent hypoglycemia may impair the hypothalamic–pituitary–adrenal axis.
Yusuf Öztürk, Mustafa Kulaksızoğlu
doaj +1 more source
Determination of islet cell antibodies using an ELISA system with a preparation of rat insulinoma (RIN A2) cells [PDF]
, 1989 An enzyme-linked immunosorbent assay (ELISA) was established for the detection of islet cell antibodies in human sera. The antigen was prepared from rat insulinoma (RIN A2) cells.
Seißler, Jochen +5 more
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Pancreatic insulinoma causing hypoglycemic episodes
Journal of Pediatric Surgery Case Reports, 2020 Background: Insulinoma typically has non-specific neuroglycopenic symptoms. It is a neuroendocrine tumor of the pancreas, and leads to recurring hypoglycemic attacks stemming from insulin hypersecretion.
Moaffaq Mahdi +3 more
doaj +1 more source