Results 51 to 60 of about 29,062 (232)

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Pancreatic insulinoma causing hypoglycemic episodes

Journal of Pediatric Surgery Case Reports, 2020
Background: Insulinoma typically has non-specific neuroglycopenic symptoms. It is a neuroendocrine tumor of the pancreas, and leads to recurring hypoglycemic attacks stemming from insulin hypersecretion.
Moaffaq Mahdi, Bassel Almehman, Safi Nassan, Soliman Binyahib   +3 more
doaj   +1 more source

Prompt Resolution of Hypoglycemia by Hepatic Transarterial Embolization for Malignant Insulinoma with Multiple Liver Metastases [PDF]

, 2014
A 45-year-old female who presented with loss of consciousness and a cold sweat was found to have a pancreatic tumor and multiple liver metastases. Laboratory studies showed marked hypoglycemia and inappropriately elevated serum insulin, C-peptide, and ...
Fujiwara, Hiroyasu, Harada, Ryo, Kanzaki, Hiromitsu, Kato, Hironari, Matsubara, Minoru, Muro, Shinichiro, Nakarai, Asuka, Nasu, Junichiro, Okada, Hiroyuki, Tanaka, Takehiro, Tsutsumi, Kouichiro, Uno, Masatoshi, Yamamoto, Kazuhide   +12 more
core   +1 more source

QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study

Advanced Science, EarlyView.
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda, Ada Bernaus Vives, Michał Wojciechowski, Dinh Quoc Huy Pham, Mateusz Chwastyk, Mario Vallejo, Anna Novials, Douglas V. Laurents, Mariano Carrión‐Vázquez   +8 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Surgical Management of Zollinger‐Ellison Syndrome in Multiple Endocrine Neoplasia Type 1 an AFCE and GTE Cohort Study. (Association Francophone de Chirurgie Endocrinienne and Groupe d'étude des Tumeurs Endocrines)

World Journal of Surgery, EarlyView.
To describe surgical indications, procedures and outcomes in patients operated for Zollinger‐Ellison syndrome (ZES) in multiple endocrine neoplasia type 1 (MEN1) using a large nationwide cohort. ABSTRACT Objective To describe surgical indications, procedures and outcomes in patients operated for Zollinger‐Ellison syndrome (ZES) in multiple endocrine ...
Sébastien Gaujoux, François Pattou, Guillaume Cadiot, Mustapha Adham, Philippe Bachellier, Jean‐Pierre Bail, Robert Caiazzo, Nicolas Carrere, Philippe Chaffanjon, Sophie Deguelte, Gianluca Donatini, Bertrand Dousset, Matthieu Faron, Caroline Gronnier, Bruno Heyd, Jean‐Christophe Lifante, Jean Lubrano, Nicolas Meurisse, Eric Mirallié, Nicolas Santucci, Alain Sauvanet, Frédéric Sebag, Laurent Sulpice, Baudoin Thebault, Jean‐Jacques Tuech, Thomas Walter, Christine Binquet, Pierre Goudet   +27 more
wiley   +1 more source

Diagnostic value of ASVS for insulinoma localization: A systematic review and meta-analysis.

PLoS ONE, 2019
BACKGROUND:Previous studies on the diagnostic value of arterial calcium stimulation with hepatic venous sampling (ASVS) for the localization of insulinoma have reported inconsistent results.
Hao Wang, Ying Ba, Qian Xing, Run-Ce Cai
doaj   +1 more source

A20 deficiency sensitizes pancreatic beta cells to cytokine-induced apoptosis in vitro but does not influence type 1 diabetes development in vivo [PDF]

, 2015
SCOPUS: ar.jinfo:eu-repo/semantics ...
Beyaert, Rudi, Cardozo, AK, Catrysse, Leen, Fukaya, M, Meyerovich, K, Sze, Mozes, van Loo, Geert   +6 more
core   +2 more sources

Insulinoma

Jurnal RSMH Palembang, 2020
A B S T R A C TInsulinoma is a functional neuroendocrine neoplasm consisting of insulin-producingcells, which produce insulin uncontrollably, causing a hypoglycemic syndrome. TheHypoglycemic syndrome is a result of hyperinsulinemia which causes adrenergicsymptoms and neuroglycopenia.
Ria Yuniarti, null Suly Auline
openaire   +4 more sources

Clinical paradox: insulinoma in a patient with type 1 diabetes mellitus

Сахарный диабет
Insulinoma is a rare neuroendocrine tumor occurring from beta-cells of the pancreas. Тhe diagnosis of insulinoma may be difficult, especially in patients with concomitant diabetes mellitus.
A. S. Ametov, M. M. Tavobilov, A. A. Karpov, E. I. Zakurdaev, E. Y. Pashkova, D. M. Antsiferova   +5 more
doaj   +1 more source