Insulinoma: presentación neuro psiquiátrica, caso clínico y revisión de la literatura
Revista Médica Clínica Las Condes, 2022 Resumen: Antecedentes: el insulinoma es un tumor infrecuente que desencadena cuadros de hipoglicemia manifestados por los clásicos síntomas vegetativos y neuroglucopénicos.
Luis Ángel Rodríguez +1 more
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Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells [PDF]
, 2019 Pancreatic β-cells are sensitive to fluctuations in cholesterol content, which can damage the insulin secretion pathway, contributing to the aetiology of type 2 diabetes mellitus.
Caridis, Anna Maria +4 more
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Lentiviral vectors with amplified beta cell-specific gene expression. [PDF]
, 2009 An important goal of gene therapy is to be able to deliver genes, so that they express in a pattern that recapitulates the expression of an endogenous cellular gene.
Crooks, GM +7 more
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Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application [PDF]
, 2016 Background The insulinoma associated protein tyrosine phosphatase 2 (IA-2) is one of the immunodominant autoantigens involved in the autoimmune attack to the beta-cell in Type 1 Diabetes Mellitus.
A Trabucchi +95 more
core +5 more sources
A novel diagnostic model for insulinoma
Discover Oncology, 2022 The aim is to describe a simple and feasible model for the diagnosis of insulinoma. This retrospective study enrolled 37 patients with insulinoma and 44 patients with hypoglycemia not due to insulinoma at the First Affiliated Hospital of Guangxi Medical ...
Feng Wang +5 more
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Sri Lanka Journal of Medicine, 2022 Insulinoma is a rare neuroendocrine tumour arising from beta cells of pancreatic islets of Langerhans. We report a case of insulinoma presented with vague manifestations, which were undiagnosed for 2 years.
S. Ubhayasiri, G. Premawansa
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Neurofibromatosis and insulinoma [PDF]
Postgraduate Medical Journal, 1995 AbstractA 45-year-old man with neurofibromatosis presented with recurrent seizures due to hypoglycaemia caused by an insulinoma. The attacks were abolished after the successful removal of the insulinoma. This probably represents another example of the association between neurofibromatosis and a tumour consisting of cells with amine-precursor-uptake and
Fung, JWK, Lam, KSL
openaire +3 more sources
Rapid intraoperative insulin assay: a novel method to differentiate insulinoma from nesidioblastosis in the pediatric patient [PDF]
, 2007 Introduction: Hyperinsulinism is the most common cause of recurrent and persistent hypoglycemia in infancy and childhood. Causes can include nesidioblastosis, pancreatic islet cell tumors such as insulinoma, and associations with multiple endocrine ...
Vivian E Strong +20 more
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Robotic enucleation for pediatric insulinoma with MEN1 syndrome: a case report and literature review
BMC Surgery, 2018 Background A patient with a rare pediatric insulinoma and MEN1 syndrome was treated by robotic enucleation surgery. Case presentation We present a case of a 9-year-old girl presenting with repeated loss of consciousness, concomitant with a pale face ...
Mei Liang +13 more
doaj +1 more source
Differential interaction of glimepiride and glibenclamide with the β-cell sulfonylurea receptor I. Binding characteristics [PDF]
, 1994 Glimepiride is a novel sulfonylurea drug for treatment of non-insulin-dependent diabetes mellitus with higher blood sugar lowering efficacy in diabetic patients than glibenclamide raising the question whether this characteristics is in line with ...
Aguilar-Bryan +35 more
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