Results 61 to 70 of about 34,487 (256)
Clinical paradox: insulinoma in a patient with type 1 diabetes mellitus
Сахарный диабетInsulinoma is a rare neuroendocrine tumor occurring from beta-cells of the pancreas. Тhe diagnosis of insulinoma may be difficult, especially in patients with concomitant diabetes mellitus.
A. S. Ametov +5 more
doaj +1 more source
Diagnostic value of ASVS for insulinoma localization: A systematic review and meta-analysis.
PLoS ONE, 2019 BACKGROUND:Previous studies on the diagnostic value of arterial calcium stimulation with hepatic venous sampling (ASVS) for the localization of insulinoma have reported inconsistent results.
Hao Wang, Ying Ba, Qian Xing, Run-Ce Cai
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 2005 O insulinoma é doença rara que cursa com sintomas episódicos neuroglicopênicos e/ou adrenérgicos. Descrevemos o caso de uma paciente de 36 anos, que estava sendo tratada por crises convulsivas parciais complexas há 4 anos sem melhora do quadro ...
Carlos Alexandre Twardowschy +3 more
doaj +1 more source
Problems of Endocrinology, 2009 According to official statistics, malignant insulinomas account for a small fraction of gastroenteropathic endocrine neoplasms, the majority of insulinomas being essentially benign tumours. This paper reports a clinical case of malignant insulin-producing neuroendocrine tumour of the pancreas tail in a 28 year-old woman.
E A, Troshina +5 more
openaire +2 more sources
Acta Paediatrica, EarlyView.ABSTRACT Aim We aimed to investigate if the incidence of type 1 diabetes increased in children during the SARS‐CoV‐2 pandemic and whether SARS‐CoV‐2 antibodies were more frequently present at diagnosis compared with healthy individuals. We also examined whether clinical characteristics and coexisting autoimmunity differed between SARS‐CoV‐2 antibody ...
J. Anderberg +4 more
wiley +1 more source
Lentiviral vectors with amplified beta cell-specific gene expression. [PDF]
, 2009 An important goal of gene therapy is to be able to deliver genes, so that they express in a pattern that recapitulates the expression of an endogenous cellular gene.
Crooks, GM +7 more
core +2 more sources
Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1
DEN Open, Volume 6, Issue 1, April 2026.ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa +9 more
wiley +1 more source
Diabetes/Metabolism Research and Reviews, Volume 42, Issue 1, January 2026.ABSTRACT Timely diagnosis of type 1 diabetes (T1D), especially in high‐risk populations, is crucial for preventing serious health complications. T1D is a chronic progressive autoimmune disease that has presymptomatic stages that can be identified through the detection of islet autoantibodies. Given that T1D is associated with other autoimmune diseases,
Nick Thomas +8 more
wiley +1 more source
Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis. [PDF]
PLoS ONE, 2016 The Jagn1 protein was indentified in a SILAC proteomic screen of proteins that are increased in insulinoma cells expressing a folding-deficient proinsulin.
Courtney Nosak +7 more
doaj +1 more source
Type 1 Diabetes and Other Autoimmune Diseases—Epidemiology, Pathophysiology and Screening
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.Individuals with type 1 diabetes exhibit significantly increased prevalence of additional autoimmune diseases. Epidemiological, familial and mechanistic evidence indicates frequent polyautoimmunity and shared genetic and environmental drivers. Coexistence complicates clinical management, and autoantibody‐based detection often identifies preclinical ...
George J. Kahaly +6 more
wiley +1 more source