Results 71 to 80 of about 34,184 (259)

Dissociation between the effects of somatostatin (SS) and octapeptide SS-analogs on hormone release in a small subgroup of pituitary- and islet cell tumors [PDF]

, 1997
The effects of somatostatin (SS-14 and/or SS-28) and of the three octapeptide SS-analogs that are available for clinical use (octreotide, BIM-23014 and RC-160) on hormone release by primary cultures of 15 clinically ...
Herder, W.W. (Wouter) de, Hofland, L.J. (Leo), Koetsveld, P.M. (Peter) van, Kros, J.M. (Johan), Lamberts, S.W.J. (Steven), Uffelen, C. van, Uitterlinden, P. (Piet), Visser-Wisselaar, H.A. (Heleen), Waaijers, M. (Marlijn), Zuyderwijk, J.   +9 more
core   +3 more sources

A Case Report of Insulinoma Treated for Refractory Seizures

Journal of Medical Sciences and Health, 2018
Insulinoma is a functional endocrine tumor of the pancreas that secretes insulin. Insulinoma comprises 25% of the pancreatic endocrine tumors. Patients may have heterogeneous presentation of symptoms varying from mild autonomic symptoms to severe ...
Shreemit Maheshwari, Suhas Chandran, D Ramya Shruthi, Rajesh Raman, T S Sathyanarayana Rao   +4 more
doaj  

Insulinoma in pregnancy (a case presentation and systematic review of the literature)

Rare Tumors, 2021
Insulinomas are rare, benign and functional tumors that coincidentally may become overt during pregnancy or in the post-partum period. As the general symptoms of a pregnancy might cover the clinical presentation, diagnosing remains challenging.
Eva M Dobrindt, Martina Mogl, Peter E Goretzki, Johann Pratschke, Agata K Dukaczewska   +4 more
doaj   +1 more source

Blue‐Gray Papules on the Chest and Face

JEADV Clinical Practice, EarlyView.
Sanjana Likki, Kevin Lee, Priyadharsini Nagarajan, Doina Ivan, Woo Cheal Cho, Fiorinda Muhaj   +5 more
wiley   +1 more source

Nonsteroidal Anti‐Inflammatory Drugs as Modulators of Cation Channels: Fenamates Repurposing in Channelopathies

ChemMedChem, Volume 20, Issue 20, October 15, 2025.
Beyond their established role as nonsteroidal anti‐inflammatory drugs (NSAIDs), fenamates (niflumic, flufenamic, mefenamic, meclofenamic, and tolfenamic acids) have recently been identified as modulators of cationic ion channels. This review highlights their differential effects on ion channel activity and explores their potential for repurposing in ...
Paola Laghetti, Concetta Altamura, Simone Dell’Atti, Jean‐François Desaphy, Ilaria Saltarella   +4 more
wiley   +1 more source

Whole exome sequencing of insulinoma reveals recurrent T372R mutations in YY1 [PDF]

, 2013
Functional pancreatic neuroendocrine tumours (PNETs) are mainly represented by insulinoma, which secrete insulin independent of glucose and cause hypoglycaemia. The major genetic alterations in sporadic insulinomas are still unknown.
Cai, Jie, Cao, Yanan, Gao, Zhibo, Huang, Xuanlin, Jiang, Xiaohua, Jiang, Xiuli, Jin, Xiaolong, Li, Lin, Li, Yanli, Li, Yingrui, Liu, Li, Ning, Guang, Peng, Ying, Qin, Guijun, Shan, Aijing, Wang, Jiaqian, Wang, Jun, Wang, Weiqing, Wei, Qing, Zhao, Jiajun   +19 more
core   +1 more source

Unraveling the Role of MDK‐SDC4 Interaction in Pancreatic Cancer‐Associated New‐Onset Diabetes by Single‐Cell Transcriptomic Analysis

Advanced Science, Volume 12, Issue 39, October 20, 2025.
Midkine (MDK) is a mediator of the interaction between pancreatic cancer and beta cells. MDK, which originated from pancreatic ductal adenocarcinoma cells, exerted deleterious effects on paraneoplastic beta cells by binding to the SDC4 receptor on the beta cell surface and subsequently downregulating the Ras signaling pathway, thereby impairing insulin
Zengyu Feng, Jianyao Lou, Chuanshuai Lin, Haocheng Yu, Yuheng Tu, Jiali Gong, Xiawei Li, Yulian Wu   +7 more
wiley   +1 more source

Insulinoma detectado por ultrasonografía endoscópica: reporte de un caso [PDF]

, 2007
Los insulinomas son tumores de las células de los islotes del páncreas que desarrollan síntomas de hipoglucemia debido a una secreción inapropiada de insulina.
Garza Galindo, Aldo Azael, Leos García, Alejandro, Villarreal Pérez, Jesús Zacarías   +2 more
core  

Are We Ready With Prevention for Type 1 Diabetes?

Diabetes/Metabolism Research and Reviews, Volume 41, Issue 7, October 2025.
ABSTRACT Definitive prevention for type 1 diabetes (T1D) is not yet available, but we are now entering a new era where disease‐modifying therapies are becoming available in T1D to halt disease progression. In this review, we present up‐to‐date knowledge related to the prevention of T1D in youth, involving disease‐modifying therapies at different T1D ...
Evelina Maines, Roberto Franceschi, Francesca di Candia, Enza Mozzillo   +3 more
wiley   +1 more source

Human fur gene encodes a yeast KEX2-like endoprotease that cleaves pro-beta-NGF in vivo. [PDF]

, 1990
Extracts from BSC-40 cells infected with vaccinia recombinants expressing either the yeast KEX2 prohormone endoprotease or a human structural homologue (fur gene product) contained an elevated level of a membrane-associated endoproteolytic activity that ...
Barr, P, Brake, A, Bresnahan, P, Gibson, H, Leduc, R, Thomas, G, Thomas, L, THORNER, Jeremy W.   +7 more
core   +1 more source