Results 71 to 80 of about 30,427 (262)

Insulinoma Manifesting Early Postpartum: Case Report and Review of the Literature

AACE Clinical Case Reports, 2015
: Objective: Insulinomas are insulin-producing neuroendocrine tumors. Insulinomas presenting during pregnancy and the early postpartum period are very rare.Methods: A 33-year-old woman with hypoglycemia early postpartum is described.
Eske Christiane Gertje, MD, Annemiek M.E. Walenkamp, MD, PhD, Andor W.J.M. Glaudemans, MD, Sander A.J.C. Ijtsma, MD, Klaas Hoogenberg, MD, PhD, Robin P.F. Dullaart, MD, PhD   +5 more
doaj   +1 more source

Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis. [PDF]

PLoS ONE, 2016
The Jagn1 protein was indentified in a SILAC proteomic screen of proteins that are increased in insulinoma cells expressing a folding-deficient proinsulin.
Courtney Nosak, Pamuditha N Silva, Pietro Sollazzo, Kyung-Mee Moon, Tanya Odisho, Leonard J Foster, Jonathan V Rocheleau, Allen Volchuk   +7 more
doaj   +1 more source

Clinical Management of Malignant Insulinoma: a single Institution’s experience over three decades

BMC Endocrine Disorders, 2018
BackgroundMalignant insulinoma is extremely rare and accounts for only 10% of total insulinoma cases. The goal of this study is to retrospectively analyze clinical data from 15 patients with malignant insulinoma treated at Peking Union Medical College ...
Jie Yu, F. Ping, Huabing Zhang, Wei Li, T. Yuan, Yong Fu, Kai Feng, W. Xia, Lingling Xu, Yuxiu Li   +9 more
semanticscholar   +1 more source

Insulinoma in Patients with Diabetes- A Systematic Review of Previously Reported Cases

Indian Journal of Endocrinology and Metabolism
Introduction: Paradoxical co-existence of insulinoma and diabetes is extremely rare. Although a few case reports addressed this association, a comprehensive study elucidating this relationship has been lacking.
Subhankar Chatterjee, Rana Bhattacharjee, Ritwik Ghosh, Partha P. Chakraborty, Anirban Sinha, Animesh Maiti   +5 more
doaj   +1 more source

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression

Scientific Reports, 2017
The angiogenic switch, the time at which a tumor becomes vascularized, is a critical step in tumor progression. Indeed, without blood supply, tumors will fail to grow beyond 1 mm3 and are unlikely to disseminate.
A. Naba, A. Naba, K. Clauser, D. Mani, S. Carr, R. Hynes   +5 more
semanticscholar   +1 more source

Pancreatic Neuroendocrine Tumor Leading to a Diagnosis of Multiple Endocrine Neoplasia Type 1

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Pancreatic neuroendocrine neoplasms are rare but occasionally encountered. They are generally highly vascularized solid tumors, often round in shape with clear boundaries, defined contours, and a homogeneous internal structure. However, they can also present with atypical features, such as cystic degeneration, hemorrhage, calcification, and ...
Noriyuki Hirakawa, Katsuya Kitamura, Kei Yamamoto, Kenichi Tadokoro, Yasunosuke Akita, Jun Uemura, Fumito Yamanishi, Masakazu Abe, Munehide Nakatsugawa, Takao Itoi   +9 more
wiley   +1 more source

A Case Report of Insulinoma Treated for Refractory Seizures

Journal of Medical Sciences and Health, 2018
Insulinoma is a functional endocrine tumor of the pancreas that secretes insulin. Insulinoma comprises 25% of the pancreatic endocrine tumors. Patients may have heterogeneous presentation of symptoms varying from mild autonomic symptoms to severe ...
Shreemit Maheshwari, Suhas Chandran, D Ramya Shruthi, Rajesh Raman, T S Sathyanarayana Rao   +4 more
doaj  

A case of insulinoma with hypoglycemia that was better managed with lanreotide than octreotide

Clinical Case Reports, 2021
Long‐acting somatostatin analogs, including lanreotide slow release (LAN‐SR) and octreotide long‐acting release (OCT‐LAR), can improve hypoglycemia in insulinoma. LAN‐SR may be more beneficial in some patients with insulinoma than OCT‐LAR.
Keiko Yamaoka, Shuichi Nagashima, Nobukazu Okada, Nagisa Sawayama, Shinsuke Saito, Manabu Takahashi, Kenta Okada, Kazuhiro Endo, Masaru Koizumi, Hideki Sasanuma, Ken Ebihara, Atsuko Kasajima, Noriyoshi Fukushima, Naohiro Sata, Shun Ishibashi   +14 more
doaj   +1 more source

Human Polyomavirus BK Genome Analysis in BKPyV Induced Rodent Cell Lines

MicrobiologyOpen, Volume 14, Issue 5, October 2025.
In this study, we analyzed the BK polyomavirus (BKPyV) genome derived from three rodent cell lines established from BKPyV induced tumors. BKPyV derived one cell line had a large deletion. The noncoding control region (NCCR) of BKPyV derived from these cell lines had the same structure as viruses induced tumors.
Setsuko Shioda, Fumio Kasai, Midori Ozawa, Azusa Ohtani, Masashi Iemura, Ken Watanabe, Arihiro Kohara   +6 more
wiley   +1 more source

Unmasked insulinoma occasioned by severe hypoglycemic coma immediately postpartum: a case report

BMC Endocrine Disorders, 2023
Background Insulinoma in women during pregnancy and postpartum is very rare; approximately 65% of cases are diagnosed early in pregnancy and ~ 35% immediately after delivery, few being found in middle or late pregnancy, likely due to increased insulin ...
Kiyoshi Matsumoto, Miyu Watanabe, Ken Takao, Hirokazu Takahashi, Hisashi Daido, Toshiro Shibata, Tokuyuki Hirose, Takehiro Kato, Masami Mizuno, Takuo Hirota, Tetsuya Suwa, Yukio Horikawa, Takaaki Murakami, Daisuke Yabe   +13 more
doaj   +1 more source