Results 71 to 80 of about 20,218 (204)

Small Extracellular Vesicles From Human Amniotic Membrane Mesenchymal Stem Cells Rejuvenate Senescent β Cells and Cure Age‐Related Diabetes in Mice

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
hAMSC‐sEVs rejuvenate β cells and improve glycaemic control via the miR‐21‐5p/IL‐6RA/STAT3/MCU axis, restoring mitochondrial Ca2+ homeostasis and insulin secretion in aged T2DM mice. ABSTRACT Targeting senescent pancreatic β‐cells represents a promising therapeutic avenue for age‐related diabetes; however, current anti‐senescence strategies often ...
Lei Xiao   +8 more
wiley   +1 more source

NERP‐4–Deleted VGF Impairs β‐Cell Granulogenesis and Insulin Secretion

open access: yesThe FASEB Journal, Volume 39, Issue 24, 31 December 2025.
Neuroendocrine regulatory peptide‐4 (NERP‐4) processed from the VGF promotes insulin secretion and β‐cell maintenance by acting on the amino acid transporter SNAT2. VGF△NERP‐4 impaired β‐cell granulogenesis and granule replenishment needed for the second‐phase insulin secretion.
Weidong Zhang   +8 more
wiley   +1 more source

Insulinoma Associated with MEN1 Syndrome: A Case of Persistent Hypoglycemia in a School-aged Child

open access: yesJCRPE
Insulinoma is a rare cause of non-ketotic hypoglycemia, both in adults and in children. Pediatric patients account for approximately 5% of all cases, mostly due to isolated benign lesions, but insulinoma may also be part of a multiple endocrine neoplasia
Rodrigo Lemus-Zepeda   +4 more
doaj   +1 more source

Clinical characteristics and treatment outcomes of patients with insulinoma–a single center's experience of 76 cases over a 10-year period

open access: yesHeliyon
Objective: Insulinoma is a rare pancreatic neuroendocrine neoplasm caused by pancreatic beta cell tumor or beta cell proliferation resulting in excessive insulin secretion.
Wei Li   +4 more
doaj   +1 more source

Insulinoma.

open access: yesJournal of postgraduate medicine, 1993
A case of insulinoma who had episoic bizarre behaviour is presented here. Pre-operative fasting and two hour post-prandial blood sugar values indicated hypoglycemia with inappropriately high insulin levels. USG and CT scan of the abdomen revealed a tumor of head of the pancreas. The tumour was enucleated surgically.
P J, Halder   +3 more
openaire   +1 more source

Varied presentation of hyperinsulinaemic hypoglycaemia [PDF]

open access: yesJournal of Clinical and Scientific Research, 2012
Hypoglycaemia is a fairly common clinical entity, mainly due to its high prevalence as a complication of therapy for diabetes. Spontaneous hypoglycemia with unsuppressed plasma insulin is a relatively uncommon endocrine disorder.
K.V. Sreedhar Babu   +8 more
doaj  

Sporadic Insulinoma as a Rare Cause of Recurrent Hypoglycemia in Children

open access: yesCase Reports in Pediatrics, 2017
Insulinoma is a rare pancreatic tumor in children and adolescents. As a result of insulin hypersecretion, signs and symptoms are more commonly consequences of the pathophysiologic responses to hypoglycemia.
Hedyeh Saneifard   +4 more
doaj   +1 more source

Insulinoma: Una visión general.

open access: diamond, 2022
José Pablo Madrigal Calderón   +3 more
openalex   +2 more sources

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