Results 71 to 80 of about 20,218 (204)
hAMSC‐sEVs rejuvenate β cells and improve glycaemic control via the miR‐21‐5p/IL‐6RA/STAT3/MCU axis, restoring mitochondrial Ca2+ homeostasis and insulin secretion in aged T2DM mice. ABSTRACT Targeting senescent pancreatic β‐cells represents a promising therapeutic avenue for age‐related diabetes; however, current anti‐senescence strategies often ...
Lei Xiao +8 more
wiley +1 more source
NERP‐4–Deleted VGF Impairs β‐Cell Granulogenesis and Insulin Secretion
Neuroendocrine regulatory peptide‐4 (NERP‐4) processed from the VGF promotes insulin secretion and β‐cell maintenance by acting on the amino acid transporter SNAT2. VGF△NERP‐4 impaired β‐cell granulogenesis and granule replenishment needed for the second‐phase insulin secretion.
Weidong Zhang +8 more
wiley +1 more source
Insulinoma Associated with MEN1 Syndrome: A Case of Persistent Hypoglycemia in a School-aged Child
Insulinoma is a rare cause of non-ketotic hypoglycemia, both in adults and in children. Pediatric patients account for approximately 5% of all cases, mostly due to isolated benign lesions, but insulinoma may also be part of a multiple endocrine neoplasia
Rodrigo Lemus-Zepeda +4 more
doaj +1 more source
Objective: Insulinoma is a rare pancreatic neuroendocrine neoplasm caused by pancreatic beta cell tumor or beta cell proliferation resulting in excessive insulin secretion.
Wei Li +4 more
doaj +1 more source
A case of insulinoma who had episoic bizarre behaviour is presented here. Pre-operative fasting and two hour post-prandial blood sugar values indicated hypoglycemia with inappropriately high insulin levels. USG and CT scan of the abdomen revealed a tumor of head of the pancreas. The tumour was enucleated surgically.
P J, Halder +3 more
openaire +1 more source
Multifocal insulinoma secondary to insulinomatosis: persistent hypoglycaemia despite total pancreatectomy [PDF]
Jennifer Snaith +3 more
openalex +1 more source
Varied presentation of hyperinsulinaemic hypoglycaemia [PDF]
Hypoglycaemia is a fairly common clinical entity, mainly due to its high prevalence as a complication of therapy for diabetes. Spontaneous hypoglycemia with unsuppressed plasma insulin is a relatively uncommon endocrine disorder.
K.V. Sreedhar Babu +8 more
doaj
Sporadic Insulinoma as a Rare Cause of Recurrent Hypoglycemia in Children
Insulinoma is a rare pancreatic tumor in children and adolescents. As a result of insulin hypersecretion, signs and symptoms are more commonly consequences of the pathophysiologic responses to hypoglycemia.
Hedyeh Saneifard +4 more
doaj +1 more source

