Results 131 to 140 of about 1,475,999 (336)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Consistent string backgrounds and completely integrable 2D field theories [PDF]

, 1995
After reviewing the $\beta$-function equations for consistent string backgrounds in the $\sigma$-model approach, including metric and antisymmetric tensor, dilaton and tachyon potential, we apply this formalism to WZW models.
Bilal, Adel
core   +1 more source

Massive Integrable Soliton Theories

, 1994
Massive integrable field theories in $1+1$ dimensions are defined at the Lagrangian level, whose classical equations of motion are related to the ``non-abelian'' Toda field equations.
Adkins, Aratyn, Bakas, Balog, Balog, de Groot, de Vega, de Vega, Dorey, Dynkin, Feher, Frappat, Gawedski, Gawedski, Gervais, Getmanov, J.Luis Miramontes, Karabali, Karabali, Leznov, Olive, Park, Park, Q-Han Park, Skyrme, Timothy J. Hollowood, Zamolodchikov, Zamolodchikov   +27 more
core   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Entanglement content of quantum particle excitations. Part II. Disconnected regions and logarithmic negativity

Journal of High Energy Physics, 2019
In this paper we study the increment of the entanglement entropy and of the (replica) logarithmic negativity in a zero-density excited state of a free massive bosonic theory, compared to the ground state.
Olalla A. Castro-Alvaredo, Cecilia De Fazio, Benjamin Doyon, István M. Szécsényi   +3 more
doaj   +1 more source

MONODROMY TRANSFORM APPROACH IN THE THEORY OF INTEGRABLE REDUCTIONS OF EINSTEIN'S FIELD EQUATIONS AND SOME APPLICATIONS [PDF]

, 2008
GEORGE ALEKSEEV
openalex   +1 more source

CSF Levels of NPTX2 Are Associated With Less Brain Atrophy Over Time in Cognitively Unimpaired Individuals

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez, Corinne Pettigrew, Yuxin Zhu, Claire Anderson, Guray Erus, Christos Davatzikos, Michael Miller, Abhay Moghekar, Sungtaek Oh, Chan‐Hyun Na, Marilyn Albert, Paul Worley, Anja Soldan   +12 more
wiley   +1 more source

Gauging the diamond: integrable coset models from twistor space

Journal of High Energy Physics
Recent work has shown that certain integrable and conformal field theories in two dimensions can be given a higher-dimensional origin from holomorphic Chern-Simons in six dimensions. Along with anti-self-dual Yang-Mills and four-dimensional Chern-Simons,
Lewis T. Cole, Ryan A. Cullinan, Ben Hoare, Joaquin Liniado, Daniel C. Thompson   +4 more
doaj   +1 more source