Results 71 to 80 of about 783,161 (291)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Studying a system of non-local condition hyperbolic equations

Қарағанды университетінің хабаршысы. Математика сериясы
Local boundary value problems for hyperbolic differential equations have been studied in considerable detail. However, the mathematical modeling of a number of real-world processes leads to nonlocal boundary value problems involving nonlinear hyperbolic
Y.A. Sharifov, A.R. Mammadli
doaj   +1 more source

Boundary value problems for n-th order differential inclusions with four-point integral boundary conditions [PDF]

Opuscula Mathematica, 2012
In this paper, we discuss the existence of solutions for a four-point integral boundary value problem of \(n\)-th order differential inclusions involving convex and non-convex multivalued maps. The existence results are obtained by applying the nonlinear
Bashir Ahmad, Sotiris K. Ntouyas
doaj   +1 more source

Localized direct segregated boundary-domain integral equations for variable-coefficient transmission problems with interface crack [PDF]

, 2011
The full text of the published article can be accessed at the link belowSome transmission problems for scalar second order elliptic partial differential equations are considered in a bounded composite domain consisting of adjacent anisotropic subdomains ...
Chkadua, O, Mikhailov, SE, Natroshvili, D   +2 more
core  

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

On some higher order boundary value problems at resonance with integral boundary conditions

Arab Journal of Mathematical Sciences, 2018
This paper investigates the existence of solutions for higher-order multipoint boundary value problems at resonance. We obtain existence results by using coincidence degree arguments.
Samuel Azubuike Iyase, Olawale Joshua Adeleke   +1 more
doaj   +1 more source

Path Integral on Star Graph

, 2012
In this paper we study path integral for a single spinless particle on a star graph with N edges, whose vertex is known to be described by U(N) family of boundary conditions.
Albeverio, Asorey, Asorey, Asorey, Bachas, Bajnok, Bastianelli, Bastianelli, Bastianelli, Bastianelli, Bauch, Bellazzini, Bellazzini, Blinder, Carreau, Cheon, Cheon, Clark, Dowker, Farhi, Fülöp, Fülöp, Gamboa, Gaveau, Goovaerts, Grosche, Horvathy, Kuchment, Laidlaw, Lal, Lawande, Leinaas, Nayak, Ohya, Ohya, Oshikawa, Oshikawa, Satoshi Ohya, Schubert, Schulman, Schulman, Schulman, Tanimura, Viñas, Wong   +44 more
core   +1 more source

PARTIAL DIFFERENTIAL EQUATIONS WITH INTEGRAL BOUNDARY CONDITIONS

Computers & Mathematics with Applications, 1983
AbstractHyperbolic nonconservative partial differential equations, such as the Von Foerster system, in which boundary conditions may depend upon the dependent variable (integral boundary conditions, for example) are solved by an approximation method based on similar work of the author for (nonlinear stochastic) ordinary differential equations.
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Analytic structure of radiation boundary kernels for blackhole perturbations

, 2005
Exact outer boundary conditions for gravitational perturbations of the Schwarzschild metric feature integral convolution between a time-domain boundary kernel and each radiative mode of the perturbation. For both axial (Regge-Wheeler) and polar (Zerilli)
Chandrasekhar S., Nollert H.-P., Olver F. W. J., Ronveaux A., Slavyanov S. Y., Stephen R. Lau, Watson G. N.   +6 more
core   +1 more source