Results 111 to 120 of about 1,350,314 (331)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Solvability of an Integral Equation of Volterra-Wiener-Hopf Type

open access: yesAbstract and Applied Analysis, 2014
The paper presents results concerning the solvability of a nonlinear integral equation of Volterra-Stieltjes type. We show that under some assumptions that equation has a continuous and bounded solution defined on the interval 0,∞ and having a finite ...
Nurgali K. Ashirbayev   +2 more
doaj   +1 more source

Integral equation models for solvent in macromolecular crystals. [PDF]

open access: yesJ Chem Phys, 2022
Gray JG   +3 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Numerical method for solving scalar problem of monochromatic wave scattering from a screen with nonlinear transmission conditions

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки
Background. The purpose of the study is to develop a numerical approach for solving the scalar diffraction problem on a flat screen with nonlinear transmission conditions. Material and methods.
V.O. Nesterov, A.A. Tsupak
doaj   +1 more source

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