Results 81 to 90 of about 1,283,580 (337)

The Theory of Integral Equations [PDF]

open access: yesProceedings of the London Mathematical Society, 1907
n ...
openaire   +2 more sources

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Constructive method for solvability of Fredholm equation of the first kind

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2017
The solvability and construction of the general solution of the first kind Fredholm integral equation are among the insufficiently explored problems in mathematics. There are various approaches to solve this problem.
Serikbai Aisagaliev, Zhanat Zhunussova
doaj   +1 more source

On the solvability of the scalar monochromatic wave diffraction problem on an inhomogeneous solid with specific transmission conditions

open access: yesИзвестия высших учебных заведений. Поволжский регион: Физико-математические науки, 2023
Background. The purpose of this work is to study the 3-D scalar problem of scattering a plane wave from an inhomogeneous solid covered with an infinitely thin layer of graphene. Material and methods.
Aleksey A. Tsupak
doaj   +1 more source

Optimal Control Problems of Forward-Backward Stochastic Volterra Integral Equations [PDF]

open access: yes, 2014
Optimal control problems of forward-backward stochastic Volterra integral equations (FBSVIEs in short) are formulated and studied. A general duality principle is established for linear backward stochastic integral equation and linear stochastic Fredholm ...
Shi, Yufeng   +2 more
core  

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Integral equation theory for nematic fluids

open access: yesCondensed Matter Physics, 2010
The traditional formalism in liquid state theory based on the calculation of the pair distribution function is generalized and reviewed for nematic fluids. The considered approach is based on the solution of orientationally inhomogeneous Ornstein-Zernike
M.F. Holovko
doaj   +1 more source

Some properties of the functional equation ϕ(x)=f(x)+∫0λxg(x,y,ϕ(y))dy

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1991
A discussion is given of some of the properties of the functional Volterra Integral equation ϕ(x)=f(x)+∫0λxg(x,y,ϕ(y))dy. and of the corresponding multidimensional equation.
Li. G. Chambers
doaj   +1 more source

Elucidating prognostic significance of purine metabolism in colorectal cancer through integrating data from transcriptomic, immunohistochemical, and single‐cell RNA sequencing analysis

open access: yesMolecular Oncology, EarlyView.
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim   +8 more
wiley   +1 more source

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