Results 1 to 10 of about 75,567 (173)

Drug resistance mutations to integrase inhibitors, proteinase, and reverse transcriptase inhibitors in newly diagnosed HIV-1 infections in Hebei province, China, 2018-2022. [PDF]

Front Cell Infect Microbiol
Lu X, Li Y, Liu M, Wang Y, An N, Sun D, Li Q.   +6 more
europepmc   +1 more source

Global genomic epidemiology of bla _GES-5 carbapenemase-associated integrons. [PDF]

Microb Genom
Matlock W, Shaw LP, Stoesser N.
europepmc   +1 more source

Structural basis of directionality control in large serine integrases

Shin H, Pigli Y, Peña Reyes T, Fuller JR, Olorunniji FJ, Rice PA.   +5 more
europepmc   +1 more source

Structure and function of retroviral integrase [PDF]

Nature Reviews Microbiology, 2021
A hallmark of retroviral replication is establishment of the proviral state, wherein a DNA copy of the viral RNA genome is stably incorporated into a host cell chromosome. Integrase is the viral enzyme responsible for the catalytic steps involved in this process, and integrase strand transfer inhibitors are widely used to treat people living with HIV ...
Alan Engelman, Goedele N. Maertens, Peter Cherepanov, Peter Cherepanov   +3 more
openaire   +4 more sources