Results 131 to 140 of about 84,131 (280)

Characterization of human immunodeficiency virus type 1 integrase expressed in Escherichia coli and analysis of variants with amino-terminal mutations [PDF]

, 1993
Karen A. Vincent, Viola Ellison, S A Chow, Patrick O. Brown   +3 more
openalex   +1 more source

Significance of constitutive integrase synthesis. [PDF]

Proceedings of the National Academy of Sciences, 1976
One conceivable function for constitutive integrase formation by lambda prophage is to stabilize the inserted state by catalyzing reinsertion of prophages that are accidentally excised. As this hypothesis implies a dynamic equilibrium betwen inserted and noninserted DNA, the existence of such an equilibrium is explored.
openaire   +3 more sources

Leukocyte count and new‐onset diabetes mellitus in people with HIV: A longitudinal study

HIV Medicine, EarlyView.
Abstract Objectives The risk of diabetes mellitus (DM) is increased in people with HIV. Chronic inflammation contributes to DM risk. High leukocytes are associated with DM in the general population, but in people with HIV, evidence of a leukocyte–DM association is limited. Methods We included participants of the Swiss HIV Cohort Study with new‐onset DM
Sophia C. Meyer, Zoe Klein, Isabella C. Schoepf, Christian W. Thorball, Marco Labarile, Neeltje A. Kootstra, Peter Reiss, Lene Ryom, Dominique L. Braun, Maria C. Thurnheer, Catia Marzolini, Christian R. Kahlert, Enos Bernasconi, Matthias Cavassini, Annalisa Marinosci, Jacques Fellay, Huldrych F. Günthard, Roger D. Kouyos, Bruno Ledergerber, Philip E. Tarr, the Swiss HIV Cohort Study, I Abela, K Aebi‐Popp, A Anagnostopoulos, M Battegay, E Bernasconi, DL Braun, HC Bucher, A Calmy, M Cavassini, A Ciuffi, G Dollenmaier, M Egger, L Elzi, J Fehr, J Fellay, H Furrer, CA Fux, HF Günthard, A Hachfeld, D Haerry, B Hasse, HH Hirsch, M Hoffmann, I Hösli, M Huber, D Jackson‐Perry, patient representatives, CR Kahlert, O Keiser, T Klimkait, RD Kouyos, H Kovari, K Kusejko, N Labhardt, K Leuzinger, B Martinez de Tejada, C Marzolini, KJ Metzner, N Müller, J Nemeth, D Nicca, J Notter, P Paioni, G Pantaleo, M Perreau, A Rauch, L Salazar‐Vizcaya, P Schmid, R Speck, M Stöckle, P Tarr, A Trkola, G Wandeler, M Weisser, S. Yerly   +75 more
wiley   +1 more source

Conserved residues Pro-109 and Asp-116 are required for interaction of the human immunodeficiency virus type 1 integrase protein with its viral DNA substrate [PDF]

, 1993
Meera Drelich, Markus Haenggi, Jan Mous
openalex   +1 more source

Establishment of transgenic Drosophila suzukii lines that express phiC31 integrase and carry the sepia gene as a marker for transformation

Insect Molecular Biology, EarlyView.
Germline transformation of the Drosophila suzukii se1 strain with the wild‐type sepia gene (~1.8 kb) using a piggyBac vector. Most lines show full rescue of sepia mutant eye colour. The lines express phage phiC31 integrase in the germline using a Dsnanos promoter.
Kalindu Ramyasoma Hewawasam, Akihiko Yamamoto, Maxwell J. Scott   +2 more
wiley   +1 more source

Fitness Impaired Drug Resistant HIV-1 Is Not Compromised in Cell-to-Cell Transmission or Establishment of and Reactivation from Latency

Viruses, 2014
Both the presence of latently infected cells and cell-to-cell viral transmission are means whereby HIV can partially evade the inhibitory activities of antiretroviral drugs.
Sophie M. Bastarache, Thibault Mesplède, Daniel A. Donahue, Richard D. Sloan, Mark A. Wainberg   +4 more
doaj   +1 more source

Characterization of the Functional Domains of Human Foamy Virus Integrase Using Chimeric Integrases

Molecules and Cells, 2005
Retroviral integrases insert viral DNA into target DNA. In this process they recognize their own DNA specifically via functional domains. In order to analyze these functional domains, we constructed six chimeric integrases by swapping domains between HIV-1 and HFV integrases, and two point mutants of HFV integrase.
Hak Sung, Lee, Seung Yi, Kang, Cha-Gyun, Shin   +2 more
openaire   +2 more sources

Evidence for a Role of Extraintestinal Pathogenic Escherichia coli, Enterococcus faecalis and Streptococcus gallolyticus in the Aetiology of Exudative Cloacitis in the Critically Endangered Kākāpō (Strigops habroptilus)

Molecular Ecology, EarlyView.
ABSTRACT The kākāpō is a critically endangered flightless parrot which suffers from exudative cloacitis, a debilitating disease resulting in inflammation of the vent margin or cloaca. Despite this disease emerging over 20 years ago, the cause of exudative cloacitis remains elusive.
Rebecca K. French, Stephanie J. Waller, Janelle R. Wierenga, Rebecca M. Grimwood, James Hodgkinson‐Bean, Andrew Digby, Lydia Uddstrom, Daryl Eason, Kākāpō Recovery Team, Lisa S. Argilla, Patrick J. Biggs, Adrian Cookson, Nigel P. French, Jemma L. Geoghegan   +13 more
wiley   +1 more source

SITE-SPECIFIC RECOMBINATION OF THE MYCOBACTERIUM TUBERCULOSISPROPHAGE-LIKE ELEMENT PHIRV1 [PDF]

, 2004
The site-specific recombination systems of bacteriophages and other mobile elements fall into two categories that are named for the integrase protein that catalyzes integration and excision of the phage genome.
Bibb, Lori Ann
core  

Dynamic patterns of repeats and retrotransposons in the centromeres of Humulus lupulus L.

New Phytologist, EarlyView.
Summary The centromere has a conserved function across eukaryotes; however, the associated DNA sequences exhibit remarkable diversity in both size and structure. In plants, some species possess well‐defined centromeres dominated by tandem satellite repeats and centromeric retrotransposons, while others have centromeric regions composed almost entirely ...
Lucie Horáková, Pavel Jedlička, Radim Čegan, Pavla Navrátilová, Hiroyuki Tanaka, Atsushi Toyoda, Takehiko Itoh, Takashi Akagi, Eiichiro Ono, Vojtěch Hudzieczek, Josef Patzak, Jan Šafář, Roman Hobza, Václav Bačovský   +13 more
wiley   +1 more source