Results 81 to 90 of about 52,284 (201)

Dietary counselling and exercise training for lipid management in people living with HIV: A systematic review and meta‐analysis

HIV Medicine, EarlyView.
Abstract Objectives Dyslipidaemia is highly prevalent among people living with human immunodeficiency virus (HIV) and contributes to increased cardiovascular risk. Although lifestyle interventions are recommended, evidence specific to people living with HIV remains limited. Previous reviews have primarily focused on dietary interventions or low‐density
Maki Aomori, Hitomi Maeda
wiley   +1 more source

No difference in HIV-1 integrase resistance between CSF and blood compartments Short title: HIV-1 integrase resistance in compartments

, 2021
International audienceBackground: Little is known about the HIV-1 integrase resistance in CNS. This study aimed to evaluate integrase resistance in CSF, as a marker of CNS, and compare it to the HIV resistance in plasma.
Simon, Anne, Palich, Romain, Teyssou, Elisa, Abdi, Basma, Katlama, Christine, Marcelin, Anne-Geneviève, Calvez, Vincent, Seang, Sophie, Chebbi, Mouna, Tubiana, Roland, Soulié, Cathia, Wirden, Marc, Valantin, Marc-Antoine, Sayon, Sophie   +13 more
core   +1 more source

Venezuelan migrants living with HIV in Barcelona: Migration patterns and baseline immunovirological characteristics in a retrospective cohort study

HIV Medicine, EarlyView.
Abstract Objectives To describe the sociodemographic characteristics, migration patterns and immunovirological outcomes of Venezuelan migrants living with HIV (PLWH) in Barcelona, Spain, and to compare them with other Latin American (LA) migrant PLWH. Methods We conducted a retrospective observational cohort study including LA migrant PLWH who attended
Alexy Inciarte, Elizabeth Zamora‐Clemente, Leire Berrocal, Ana González‐Cordón, Lorena De La Mora, María Martínez‐Rebollar, Montserrat Laguno, Juan Ambrosioni, Iván Chivite, Elisa de Lazzari, Alberto Foncillas, Júlia Calvo, Abiu Sempere, Esteban Martínez, José M. Miró, José Luis Blanco, Berta Torres, Josep Mallolas   +17 more
wiley   +1 more source

Real‐world use and effectiveness of fostemsavir in a US clinical setting: Insights from Trio Health HIV Research Network

HIV Medicine, EarlyView.
Abstract Objective To describe real‐world patterns of use, virologic and immunologic outcomes and treatment persistence among people with HIV (PWH) initiating fostemsavir (FTR) in a diverse US cohort. Design Retrospective cohort study of adults receiving FTR in clinical practice, stratified by baseline viral suppression status.
Richard Elion, Cassidy Henegar, Isobel McEwen, Andrew Frick, Moti Ramgopal, Steven Santiago, Karam Mounzer, Gregory Huhn, Charles Walworth, Leigh Ragone, Vani Vannappagari   +10 more
wiley   +1 more source

Comparison Between Several Integrase-defective Lentiviral Vectors Reveals Increased Integration of an HIV Vector Bearing a D167H Mutant

Molecular Therapy: Nucleic Acids, 2014
HIV-1 derived vectors are among the most efficient for gene transduction in mammalian tissues. As the parent virus, they carry out vector genome insertion into the host cell chromatin.
Muhammad Qamar Saeed, Noelle Dufour, Cynthia Bartholmae, Urzula Sieranska, Malaika Knopf, Eloïse Thierry, Sylvain Thierry, Olivier Delelis, Nicolas Grandchamp, Héloïse Pilet, Philippe Ravassard, Julie Massonneau, Françoise Pflumio, Christof von Kalle, François Lachapelle, Alexis-Pierre Bemelmans, Manfred Schmidt, Ché Serguera   +17 more
doaj   +1 more source

Raltegravir: first in class HIV integrase inhibitor

, 2008
Zelalem Temesgen1, Dawd S Siraj21Mayo Clinic, Rochester, MN, USA; 2East Carolina University Greenville, NC, USAAbstract: On October 16, 2007, the US Food and Drug Administration (FDA) approved raltegravir for treatment of human immunodeficiency virus ...
Dawd S Siraj, Zelalem Temesgen
core  

Stability of the HIV cascade of care throughout the COVID‐19 pandemic in Europe: Results from the multinational EuroSIDA cohort study (2016–2022)

HIV Medicine, EarlyView.
Abstract Background Prior to the COVID‐19 pandemic, antiretroviral therapy (ART) coverage and viral suppression were improving across Europe; however, the impact of the pandemic on HIV care remains uncertain. Methods In‐person visits, ART coverage and viral suppression among those on ART were described in the EuroSIDA cohort for each calendar year from
Olga Fursa, Wendy Bannister, Giovanni Guaraldi, Justyna Kowalska, Jose M. Miro, Robert Zangerle, David Jilich, Jean‐Paul Viard, Katharina Kusejko, Piotr Nowak, Pere Domingo, Claire Mackintosh, Antonella Castagna, Thomas Benfield, Bartosz Szetela, Johannes Bogner, Marta Boffito, Lars Peters, on behalf of the EuroSIDA study group   +18 more
wiley   +1 more source

HIV‐associated nephropathy: A decade of clinical outcomes, global disparities and emerging promise

HIV Medicine, EarlyView.
Abstract Objective To review the pathogenesis, epidemiology, clinical presentation, management and outcomes of HIV‐associated nephropathy (HIVAN), with emphasis on global disparities, genetic susceptibility (APOL1) and emerging therapeutic and technological advances.
Deepak V. Pathiyil, Nicola Wearne, Brendon Price, Frank Post, Dami A. Collier   +4 more
wiley   +1 more source

Therapeutic Opportunities in Infectious Diseases: Highlights from the Society of Medicines Research Symposium, held on March 14th 2013 at the National Heart & Lung Institute, London, UK [PDF]

, 2013
Collingwood, S P, Pryde, D C, Anderson, RJ, Collingwood, SP, Pryde, DC, Anderson, Rosaleen, Alderton, W K, Alderton, WK   +7 more
core   +6 more sources

From biology to biotechnology: Host‐regulation factors from parasitoid wasps are a source of bioactive molecules with translational potential

Insect Molecular Biology, EarlyView.
Parasitoid wasps deploy maternal and embryonic factors to reprogramme host physiology. Venom, calyx fluid, polydnaviruses, teratocytes and larval secretions act in a coordinated, compartmentalised manner. Host‐regulation factors are promising sources of insecticidal, antimicrobial and bioinspired translational molecules.
Ciro Pedro G. Pinto, Andrew A. Walker, Glenn F. King   +2 more
wiley   +1 more source