Results 151 to 160 of about 2,826,854 (328)
A Mathematical Model for Allergic Reactions Induced by the Therapy of HIV
Mathematical Methods in the Applied Sciences, Volume 48, Issue 14, Page 13816-13838, 30 September 2025.ABSTRACT A new mathematical model for cell evolution in HIV is introduced and studied. Delay differential equations are used to capture the dynamics of immune system cells involved in allergies, as well as the evolution of HIV viruses, infected and uninfected CD4 +$$ {}^{+} $$ cells, and cytotoxic T‐lymphocytes, under specific antiretroviral therapy ...
Rawan Abdullah +3 more
wiley +1 more source
Critical appraisal of elvitegravir in the treatment of HIV-1/AIDS
HIV/AIDS: Research and Palliative Care, 2014 Krishan K PandeyInstitute for Molecular Virology, Saint Louis University Health Sciences Center, St Louis, MO, USAAbstract: Human immunodeficiency virus type 1 (HIV-1) integrase inhibitors belong to a novel class of antiretroviral drugs with high potency
Pandey KK
doaj
Approaches to repurposing reverse transcriptase antivirals in cancer
British Journal of Clinical Pharmacology, Volume 91, Issue 9, Page 2494-2506, September 2025.This review highlights the role of reverse transcriptase (RT) inhibition in cellular regulation associated with non‐terminal repeat retrotransposons and endogenous retroviruses. Based on their pleiotropic characteristics, RT inhibitors (RTIs) are discussed as potential anticancer agents.
Richard Head +2 more
wiley +1 more source
A New Class of HIV-1 Integrase Inhibitors: The 3,3,3‘,3‘-Tetramethyl-1,1‘-spirobi(indan)-5,5‘,6,6‘-tetrol Family [PDF]
, 2000 Valentina Molteni +5 more
openalex +1 more source
The Plant Genome, Volume 18, Issue 3, September 2025.Abstract Cacao (Theobroma cacao), the source of chocolate, is threatened by devastating diseases like frosty pod rot (FPR) and witches' broom disease (WBD), impacting global production and farmer livelihoods. Here, we employ a machine learning‐driven genome‐wide association study to dissect the genetic architecture of disease resistance and ...
Ezekiel Ahn +9 more
wiley +1 more source
Journal of the International Association of Providers of AIDS Care, 2019 Non-nucleoside reverse-transcriptase inhibitor plus integrase strand transfer inhibitor–based dual therapies are an attractive simplification, nucleoside reverse transcriptase inhibitor-sparing strategy for experienced human immunodeficiency virus ...
Niccolò Riccardi MD +3 more
doaj +1 more source
Intracellular Expression of Single-Chain Variable Fragments To Inhibit Early Stages of the Viral Life Cycle by Targeting Human Immunodeficiency Virus Type 1 Integrase [PDF]
, 2001 P Levy-Mintz +9 more
openalex +1 more source
Sociology of Health &Illness, Volume 47, Issue 7, September 2025.ABSTRACT In 2020, there were reports that HIV antiretrovirals, specifically the combination tenofovir disoproxil fumarate and emtricitabine (TDF/FTC), had therapeutic potential for COVID‐19. In the context of scant empirical evidence at the time to confirm such an effect, we sought to understand the ways that gay and bisexual men (GBM) made sense of ...
Daniel Storer +4 more
wiley +1 more source
Dolutegravir – a review of the pharmacology, efficacy, and safety in the treatment of HIV
Drug Design, Development and Therapy, 2015 Christopher E Kandel,1 Sharon L Walmsley1,21Department of Medicine, University of Toronto, Toronto, ON, Canada; 2Division of Infectious Diseases, University Health Network, Toronto, ON, CanadaAbstract: Dolutegravir is the newest integrase strand transfer
Kandel CE, Walmsley SL
doaj
Inhibition of Human Immunodeficiency Virus Type 1 Isolates by the Integrase Inhibitor L-731,988, a Diketo Acid [PDF]
, 2002 Ryan Reinke +2 more
openalex +1 more source